Review: taking Methadone hydrochloride and Trazodone hydrochloride together


Summary

Drug interactions are reported among people who take Methadone hydrochloride and Trazodone hydrochloride together. This review analyzes the effectiveness and drug interactions between Methadone hydrochloride and Trazodone hydrochloride. It is created by eHealthMe based on reports of 1,004 people who take the same drugs from FDA and social media, and is updated regularly.

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Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 3,248 users)

Trazodone Hydrochloride

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 8,505 users)

On Sep, 20, 2016

1,004 people who take Methadone Hydrochloride, Trazodone Hydrochloride are studied.


Number of reports submitted per year:

Methadone hydrochloride and Trazodone hydrochloride drug interactions.

Drug effectiveness over time:

Methadone Hydrochloride:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 66.0% - (4 of 6 people)
  • 6 - 12 months: 75.0% - (3 of 4 people)
  • 1 - 2 years: 50.0% - (3 of 6 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 100.0% - (3 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Trazodone Hydrochloride:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 60.0% - (3 of 5 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Methadone Hydrochloride:
  • female: 64.0% - (9 of 14 people)
  • male: 53.0% - (8 of 15 people)
Trazodone Hydrochloride:
  • female: 37.0% - (6 of 16 people)
  • male: 35.0% - (5 of 14 people)

Drug effectiveness by age:

Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 57.0% - (4 of 7 people)
  • 30-39: 50.0% - (3 of 6 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 55.0% - (5 of 9 people)
  • 60+: 0.0% - (0 of 0 people)
Trazodone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 12.0% - (1 of 8 people)
  • 30-39: 60.0% - (3 of 5 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 44.0% - (4 of 9 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • arthralgia
  • cervix carcinoma
  • dizziness
  • thirst
  • acute myocardial infarction
  • drug dependence
  • fall
  • fatigue
  • hypoxia
1 - 6 months:
  • drug dependence
  • post-traumatic stress disorder
  • somnolence
  • bone and joint pain
  • cervix carcinoma
  • constipation
  • drug abuse
  • hypotension
  • meningococcal infection
  • multiple drug overdose accidental
6 - 12 months:
  • dementia
  • diabetes mellitus
  • hyperglycaemia
  • neuropathy peripheral
  • fear
  • hallucination
  • major depression
  • paranoid personality disorder
  • abnormal behaviour
  • dental caries
1 - 2 years:
  • abnormal behaviour
  • dental caries
  • depression
  • drug dependence
  • dysarthria
  • tooth abscess
  • drug abuse
  • abdominal wall haematoma
  • anaemia
  • overdose
2 - 5 years:
  • weight increased
  • anger
  • anxiety
  • breast mass
  • cellulitis
  • clumsiness
  • constipation
  • depression
  • dyspnoea
  • eye swelling
5 - 10 years:
  • epstein-barr virus antibody positive
  • hepatitis acute
  • anxiety
  • abdominal pain
  • acute hepatic failure
  • carpal tunnel syndrome
  • cervical disc lesion
  • colitis
  • convulsion
  • depression
10+ years:
  • depression suicidal
  • high blood cholesterol and triglycerides
not specified:
  • pain
  • nausea
  • depression
  • anxiety
  • weight decreased
  • drug abuse
  • pyrexia
  • back pain
  • cardiac arrest
  • headache

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • fatigue
  • back pain
  • depression
  • dyspnoea
  • weight decreased
  • drug abuse
  • headache
male:
  • pain
  • nausea
  • pyrexia
  • depression
  • vomiting
  • drug abuse
  • weight decreased
  • fall
  • cardiac arrest
  • pneumonia

Most common drug interactions by age *:

0-1:
  • drug effect decreased
  • dysgeusia
  • gingival pain
  • glossodynia
  • hypoaesthesia oral
  • paraesthesia oral
  • tongue discolouration
2-9:
  • hypertension
  • abdominal distension
  • abdominal pain
  • abnormal behaviour
  • acrochordon
  • amnesia
  • anaemia
  • animal bite
  • anogenital warts
  • arrhythmia
10-19:
  • completed suicide
  • progressive multifocal leukoencephalopathy
  • abdominal distension
  • abnormal behaviour
  • activities of daily living impaired
  • anxiety
  • bedridden
  • behcet's syndrome
  • cardiac arrest
  • convulsion
20-29:
  • drug abuse
  • cardio-respiratory arrest
  • drug dependence
  • post-traumatic stress disorder
  • death
  • fatigue
  • diarrhoea
  • dizziness
  • hyperhidrosis
  • nausea
30-39:
  • cardiac arrest
  • nausea
  • drug abuse
  • death
  • convulsion
  • type 2 diabetes mellitus
  • pain
  • asthenia
  • atelectasis
  • respiratory arrest
40-49:
  • depression
  • pyrexia
  • pain
  • drug abuse
  • nausea
  • vomiting
  • pneumonia
  • cardiac arrest
  • diabetes mellitus
  • type 2 diabetes mellitus
50-59:
  • nausea
  • depression
  • pain
  • fall
  • anxiety
  • headache
  • weight decreased
  • confusional state
  • diarrhoea
  • neuropathy peripheral
60+:
  • pain in extremity
  • pain
  • weight decreased
  • anxiety
  • rash
  • back pain
  • dyspnoea
  • urticaria
  • tooth disorder
  • actinomycosis

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Trazodone hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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