Review: taking Methadose and Melatonin together


Summary

Drug interactions are reported among people who take Methadose and Melatonin together. This review analyzes the effectiveness and drug interactions between Methadose and Melatonin. It is created by eHealthMe based on reports of 43 people who take the same drugs from FDA and social media, and is updated regularly.

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Methadose

Methadose has active ingredients of methadone hydrochloride. It is often used in drug withdrawal maintenance therapy. (latest outcomes from Methadose 2,355 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 3,072 users)

On Jul, 22, 2016

43 people who take Methadose, Melatonin are studied.


Number of reports submitted per year:

Methadose and Melatonin drug interactions.

Drug effectiveness over time:

Methadose:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 10 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 9.0% - (1 of 11 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methadose:
  • female: 16.0% - (2 of 12 people)
  • male: 66.0% - (2 of 3 people)
Melatonin:
  • female: 0.0% - (0 of 12 people)
  • male: 33.0% - (1 of 3 people)

Drug effectiveness by age:

Methadose:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 16.0% - (2 of 12 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 1 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 12 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

1 - 6 months:
  • cataplexy
  • dystonia
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • language disorder - expressive
  • musculoskeletal pain
  • musculoskeletal stiffness
  • neuropathy - peripheral
  • numbness and tingling
  • orthostatic hypotension
  • pain - joints
6 - 12 months:
  • high blood pressure
1 - 2 years:
  • arthritis
  • pseudoporphyria
  • anxiety
  • anxiety disorder
  • constipation
  • depression
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
2 - 5 years:
  • arthritis
  • pseudoporphyria
  • anxiety
  • anxiety disorder
  • constipation
  • depression
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
not specified:
  • deformity
  • headache
  • oedema peripheral
  • constipation
  • respiratory failure
  • asthenia
  • dizziness
  • dyspnoea
  • pain
  • vomiting

Most common drug interactions by gender *:

female:
  • constipation
  • arthritis
  • headache
  • pseudoporphyria
  • dizziness
  • dyspnoea
  • pain
  • actinomyces test positive
  • acute psychosis
  • amnesia
male:
  • brain oedema
  • pulmonary oedema
  • hepatitis c
  • myalgia
  • deformity
  • drug abuse
  • dry skin
  • general physical health deterioration
  • joint stiffness
  • nephrogenic systemic fibrosis

Most common drug interactions by age *:

20-29:
  • actinomyces test positive
  • acute psychosis
  • amnesia
  • asthenia
  • bone disorder
  • breath odour
  • candidiasis
  • cellulitis
  • chronic sinusitis
  • constipation
30-39:
  • anoxic encephalopathy
  • coma
  • diabetes mellitus
  • diabetic coma
  • lung disorder
  • nervous system disorder
  • overdose
40-49:
  • arthritis
  • pseudoporphyria
  • anxiety
  • anxiety disorder
  • constipation
  • depression
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
50-59:
  • deformity
  • dry skin
  • general physical health deterioration
  • joint stiffness
  • myalgia
  • nephrogenic systemic fibrosis
  • oedema peripheral
  • pruritus
  • scab
  • scar
60+:
  • blood creatinine decreased
  • blood pressure decreased
  • hepatitis c
  • confusional state
  • muscle spasms
  • abasia
  • abdominal pain
  • abnormal loss of weight
  • asthenia
  • back pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Methadose (methadone hydrochloride) is often used to treat drug withdrawal maintenance therapy. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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