Review: taking Methadose and Propranolol hydrochloride together


Summary

Drug interactions are reported among people who take Methadose and Propranolol hydrochloride together. This review analyzes the effectiveness and drug interactions between Methadose and Propranolol hydrochloride. It is created by eHealthMe based on reports of 323 people who take the same drugs from FDA and social media, and is updated regularly.

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Methadose

Methadose has active ingredients of methadone hydrochloride. It is often used in drug abuse. (latest outcomes from Methadose 3,127 users)

Propranolol Hydrochloride

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in migraine. (latest outcomes from Propranolol hydrochloride 4,020 users)

On Sep, 16, 2016

323 people who take Methadose, Propranolol Hydrochloride are studied.


Number of reports submitted per year:

Methadose and Propranolol hydrochloride drug interactions.

Drug effectiveness over time:

Methadose:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Propranolol Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methadose:
  • female: 57.0% - (4 of 7 people)
  • male: 66.0% - (2 of 3 people)
Propranolol Hydrochloride:
  • female: 60.0% - (3 of 5 people)
  • male: 80.0% - (4 of 5 people)

Drug effectiveness by age:

Methadose:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (3 of 3 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 0 people)
Propranolol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • abdominal pain
  • acute pulmonary oedema
  • blood creatinine increased
  • cardio-respiratory arrest
  • dyspnoea
  • hypervolaemia
  • hypotension
  • pain
  • flatulence
  • ascites
1 - 6 months:
  • miosis
  • narcotic intoxication
  • respiratory depression
  • depressed level of consciousness
  • unresponsive to stimuli
  • decreased appetite
  • drug withdrawal syndrome
  • overdose
6 - 12 months:
  • drowsiness
  • flatulence
  • short-term memory loss
  • thrombocytopenia
1 - 2 years:
  • back pain
  • blood triglycerides increased
  • cardiac disorder
  • chest pain
  • hyperglycaemia
  • hyperprolactinaemia
  • musculoskeletal pain
  • oedema peripheral
  • supraventricular tachycardia
  • tachycardia
2 - 5 years:
  • depression
  • abdomen - swollen
  • breathlessness
  • constipation
  • initial insomnia
  • panic attacks
  • pitting oedema
  • postherpetic neuralgia
  • aggression
  • amnesia
5 - 10 years:
  • migraine
10+ years:
  • abdomen - swollen
  • abdominal pain
  • anxiety
  • breathlessness
  • cholecystitis chronic
  • cholelithiasis
  • constipation
  • depression
  • emotional distress
  • gastric disorder
not specified:
  • nausea
  • pain
  • anxiety
  • headache
  • convulsion
  • depression
  • fibromyalgia
  • insomnia
  • diarrhoea
  • cardiac arrest

Most common drug interactions by gender *:

female:
  • pain
  • fibromyalgia
  • nausea
  • headache
  • convulsion
  • anxiety
  • injury
  • gastrooesophageal reflux disease
  • oedema peripheral
  • abdominal pain
male:
  • cardiac arrest
  • completed suicide
  • respiratory arrest
  • anxiety
  • cardio-respiratory arrest
  • confusional state
  • depression
  • nausea
  • insomnia
  • fatigue

Most common drug interactions by age *:

0-1:
  • renal failure
  • death
  • adenovirus infection
  • bone marrow transplant rejection
  • injury
  • multi-organ failure
  • pain
  • renal failure acute
  • renal injury
  • respiratory failure
10-19:
  • completed suicide
  • cardiac arrest
  • respiratory arrest
  • cardio-respiratory arrest
  • unresponsive to stimuli
  • death
  • pulseless electrical activity
  • apnoea
  • drug maladministration
  • electrocardiogram qt corrected interval prolonged
20-29:
  • differential white blood cell count abnormal
  • nausea
  • neutrophil count decreased
  • parotid gland enlargement
  • salivary gland pain
  • vomiting
  • grand mal convulsion
  • thinking abnormal
  • affect lability
  • aggression
30-39:
  • fatigue
  • anaemia
  • cardio-respiratory arrest
  • diarrhoea
  • dyspnoea
  • nausea
  • rash
  • urinary incontinence
  • confusional state
  • contusion
40-49:
  • anxiety
  • convulsion
  • pain
  • fibromyalgia
  • asthenia
  • headache
  • pain in extremity
  • fatigue
  • insomnia
  • pneumonia
50-59:
  • depression
  • nausea
  • headache
  • oedema peripheral
  • hypertension
  • anxiety
  • anaemia
  • insomnia
  • thrombocytopenia
  • completed suicide
60+:
  • abdominal pain
  • blood creatinine increased
  • cardio-respiratory arrest
  • hypervolaemia
  • hypotension
  • sedation
  • acute pulmonary oedema
  • ascites
  • drug toxicity
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Methadose (methadone hydrochloride) is often used to treat drug abuse. Propranolol hydrochloride (propranolol hydrochloride) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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