Review: taking Methotrexate preservative free and Azasan together


Summary

Drug interactions are reported among people who take Methotrexate preservative free and Azasan together. This review analyzes the effectiveness and drug interactions between Methotrexate preservative free and Azasan. It is created by eHealthMe based on reports of 1,543 people who take the same drugs from FDA and social media, and is updated regularly.

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Methotrexate Preservative Free

Methotrexate preservative free has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate preservative free 157 users)

Azasan

Azasan has active ingredients of azathioprine. It is often used in crohn's disease. (latest outcomes from Azasan 152 users)

On Aug, 28, 2016

1,543 people who take Methotrexate Preservative Free, Azasan are studied.


Number of reports submitted per year:

Methotrexate preservative free and Azasan drug interactions.

Drug effectiveness over time:

Methotrexate Preservative Free:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 40.0% - (2 of 5 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Azasan:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methotrexate Preservative Free:
  • female: 25.0% - (3 of 12 people)
  • male: 100.0% - (1 of 1 people)
Azasan:
  • female: 25.0% - (3 of 12 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Methotrexate Preservative Free:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 33.0% - (1 of 3 people)
Azasan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • nausea
  • vomiting
  • arachnoiditis
  • arthralgia
  • arthritis
  • arthropathy
  • blood glucose increased
  • bursitis
  • constipation
1 - 6 months:
  • liver disorder
  • arthralgia
  • headache
  • hypertension
  • pancreatitis
  • pyrexia
  • bronchitis
  • urticaria
  • conjunctivitis
  • eye pain
6 - 12 months:
  • progressive multifocal leukoencephalopathy
  • drug ineffective
  • pneumonia
  • cytomegalovirus colitis
  • leukopenia
  • lymphopenia
  • pneumonia aspiration
  • pneumonia cytomegaloviral
  • urosepsis
  • abdominal pain lower
1 - 2 years:
  • arthralgia
  • arthritis
  • renal failure
  • renal failure chronic
  • abscess limb
  • asthenia
  • bronchial carcinoma
  • cholestasis
  • death
  • hypotension
2 - 5 years:
  • weight decreased
  • chest pain
  • cholestasis
  • hepatic steatosis
  • rib fracture
  • wrist fracture
  • biliary cirrhosis primary
  • ganglioneuroma
  • multiple fractures
  • sjogren's syndrome
5 - 10 years:
  • weight decreased
  • chest pain
  • pyrexia
  • asthenia
  • ovarian epithelial cancer
  • alopecia
  • bronchitis
  • gastrooesophageal reflux disease
  • sinusitis
  • adverse drug reaction
10+ years:
  • autoimmune hepatitis
  • hepatic cirrhosis
  • lactose intolerance
  • pancreatitis acute
  • abdominal pain
  • ascites
  • diarrhoea
  • hepatitis toxic
  • muscle pain
  • neck stiffness
not specified:
  • pyrexia
  • drug ineffective
  • pain
  • fatigue
  • nausea
  • arthralgia
  • diarrhoea
  • anaemia
  • oedema peripheral
  • sepsis

Most common drug interactions by gender *:

female:
  • pyrexia
  • nausea
  • arthralgia
  • pain
  • fatigue
  • diarrhoea
  • drug ineffective
  • weight decreased
  • oedema peripheral
  • anaemia
male:
  • pyrexia
  • drug ineffective
  • crohn's disease
  • sepsis
  • asthenia
  • renal failure
  • malaise
  • pain
  • abdominal pain
  • colon cancer

Most common drug interactions by age *:

0-1:
  • delayed fontanelle closure
  • hypertension
  • sepsis
2-9:
  • histiocytosis haematophagic
  • immunosuppression
  • parvovirus infection
  • crohn's disease
  • epididymitis
  • influenza
  • muscle rigidity
  • oral candidiasis
  • arthralgia
  • epstein-barr virus associated lymphoproliferative disorder
10-19:
  • cytomegalovirus infection
  • crohn's disease
  • staphylococcal bacteraemia
  • lymphadenopathy
  • acute graft versus host disease in intestine
  • epstein-barr virus infection
  • pyrexia
  • drug ineffective
  • muscle contractions involuntary
  • pneumocystis jiroveci pneumonia
20-29:
  • crohn's disease
  • arthralgia
  • liver disorder
  • hypertension
  • bronchitis
  • histiocytosis haematophagic
  • oedema peripheral
  • hypotension
  • transaminases increased
  • drug ineffective
30-39:
  • drug ineffective
  • pyrexia
  • diarrhoea
  • nausea
  • vomiting
  • headache
  • multi-organ failure
  • systemic lupus erythematosus
  • crohn's disease
  • tumour lysis syndrome
40-49:
  • arthralgia
  • pyrexia
  • mouth ulceration
  • fatigue
  • headache
  • pain
  • fall
  • hypokalaemia
  • foot fracture
  • hypoaesthesia
50-59:
  • weight decreased
  • pain
  • fatigue
  • diarrhoea
  • pleural effusion
  • oedema peripheral
  • sepsis
  • pyrexia
  • mouth ulceration
  • sinusitis
60+:
  • fatigue
  • nausea
  • drug ineffective
  • arthralgia
  • pain
  • pyrexia
  • cough
  • dyspnoea
  • fall
  • arthropathy

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Methotrexate preservative free (methotrexate sodium) is often used to treat rheumatoid arthritis. Azasan (azathioprine) is often used to treat crohn's disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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