Review: taking Methotrexate preservative free and Quetiapine fumarate together


Summary

Drug interactions are reported among people who take Methotrexate preservative free and Quetiapine fumarate together. This review analyzes the effectiveness and drug interactions between Methotrexate preservative free and Quetiapine fumarate. It is created by eHealthMe based on reports of 541 people who take the same drugs from FDA and social media, and is updated regularly.

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Methotrexate Preservative Free

Methotrexate preservative free has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate preservative free 157 users)

Quetiapine Fumarate

Quetiapine fumarate has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Quetiapine fumarate 5,827 users)

On Aug, 27, 2016

541 people who take Methotrexate Preservative Free, Quetiapine Fumarate are studied.


Number of reports submitted per year:

Methotrexate preservative free and Quetiapine fumarate drug interactions.

Drug effectiveness over time:

Methotrexate Preservative Free:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Quetiapine Fumarate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methotrexate Preservative Free:
  • female: 36.0% - (4 of 11 people)
  • male: 0.0% - (0 of 0 people)
Quetiapine Fumarate:
  • female: 55.0% - (5 of 9 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Methotrexate Preservative Free:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 66.0% - (2 of 3 people)
  • 40-49: 0.0% - (0 of 4 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 0 people)
Quetiapine Fumarate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • weight decreased
  • weight increased
  • insomnia
  • drug ineffective
  • fall
  • nausea
  • amnesia
  • gait disturbance
  • rash
1 - 6 months:
  • weight increased
  • gait disturbance
  • insomnia
  • weight decreased
  • constipation
  • nervousness
  • back pain
  • fall
  • mania
  • rib fracture
6 - 12 months:
  • alveolitis
  • transaminases increased
  • psychotic disorder
  • constipation
  • insomnia
  • blood glucose abnormal
  • bulimia nervosa
  • incontinence
  • multiple sclerosis
  • nervousness
1 - 2 years:
  • somnolence
  • memory impairment
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • fatigue
  • gait disturbance
  • hyperlipidaemia
  • insomnia
  • obesity
2 - 5 years:
  • depression
  • insomnia
  • adverse event
  • drug ineffective
  • fatigue
  • feeling abnormal
  • nausea
  • fall
  • mania
  • memory impairment
5 - 10 years:
  • type 2 diabetes mellitus
  • hyperlipidaemia
  • blood cholesterol increased
  • blood triglycerides increased
  • diabetes mellitus
  • headache - mixed tension migraine
  • hyperglycaemia
  • lightheadedness - dizzy
  • neuropathy peripheral
  • obesity
10+ years:
  • pyrexia
  • weight decreased
  • abdominal discomfort
  • abdominal pain upper
  • activities of daily living impaired
  • adverse drug reaction
  • adverse event
  • ageusia
  • agitation
  • amnesia
not specified:
  • insomnia
  • pain
  • depression
  • fatigue
  • anxiety
  • nausea
  • drug ineffective
  • vomiting
  • somnolence
  • headache

Most common drug interactions by gender *:

female:
  • insomnia
  • depression
  • nausea
  • anxiety
  • pain
  • drug ineffective
  • fatigue
  • pyrexia
  • weight decreased
  • vomiting
male:
  • malaise
  • death
  • psoriasis
  • diabetes mellitus
  • insomnia
  • pain
  • vomiting
  • diarrhoea
  • pancreatitis
  • headache

Most common drug interactions by age *:

2-9:
  • renal failure acute
  • renal failure chronic
  • abnormal behaviour
  • crying
  • electrocardiogram qt prolonged
  • localised infection
  • mood swings
  • pseudomonas infection
  • staphylococcal infection
10-19:
  • weight increased
  • injection site pain
  • rheumatoid arthritis
  • suicidal ideation
  • asthenia
  • gait disturbance
  • anxiety
  • abasia
  • adverse event
  • aphagia
20-29:
  • abdominal pain
  • crohn's disease
  • pain
  • vulvovaginal pain
  • anal abscess
  • diabetes mellitus
  • infection
  • pyrexia
  • chronic obstructive pulmonary disease
  • death
30-39:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • nausea
  • blood cholesterol increased
  • pain
  • pancreatitis
  • vomiting
  • convulsion
  • diabetes mellitus inadequate control
  • diabetic coma
40-49:
  • nausea
  • anxiety
  • rheumatoid arthritis
  • depression
  • pain
  • arthralgia
  • insomnia
  • fatigue
  • vomiting
  • pyrexia
50-59:
  • malaise
  • vomiting
  • headache
  • drug ineffective
  • insomnia
  • weight decreased
  • pyrexia
  • weight increased
  • diarrhoea
  • migraine
60+:
  • insomnia
  • depression
  • drug ineffective
  • fall
  • fatigue
  • memory impairment
  • somnolence
  • dysphonia
  • feeling jittery
  • nervousness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Methotrexate preservative free (methotrexate sodium) is often used to treat rheumatoid arthritis. Quetiapine fumarate (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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