Methotrexate and Milk thistle drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Methotrexate and Milk thistle together. This review analyzes the effectiveness and drug interactions between Methotrexate and Milk thistle. It is created by eHealthMe based on reports of 100 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Methotrexate and Milk thistle, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

Milk Thistle

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. (latest outcomes from Milk thistle 1,564 users)

On Jan, 28, 2017

100 people who take Methotrexate, Milk Thistle are studied.


Number of reports submitted per year:

Methotrexate and Milk thistle drug interactions.

Most common drug interactions over time *:

< 1 month:
  • pulmonary mass
  • pulmonary oedema
  • blood creatinine increased
  • disseminated intravascular coagulation
  • hypotension
  • lung infiltration
  • meningitis cryptococcal
  • pneumonia bacterial
  • pneumonia cryptococcal
  • respiratory acidosis
1 - 6 months:
  • liver function test abnormal
  • hepatotoxicity
  • pulmonary tuberculosis
  • acute coronary syndrome
  • acute myocardial infarction
6 - 12 months:
  • death
  • mycobacterium tuberculosis complex test positive
1 - 2 years:
  • adverse reaction
  • death
  • mycobacterium tuberculosis complex test positive
  • pneumonia
  • pulmonary mass
  • stomatitis
5 - 10 years:
  • acute coronary syndrome
  • acute myocardial infarction
not specified:
  • nausea
  • injection site pain
  • pyrexia
  • arthralgia
  • fatigue
  • pain in extremity
  • vomiting
  • headache
  • insomnia
  • blood alkaline phosphatase increased

Most common drug interactions by gender *:

female:
  • nausea
  • injection site pain
  • blood alkaline phosphatase increased
  • escherichia sepsis
  • fall
  • pain in extremity
  • pulmonary tuberculosis
  • uterine polyp
  • vomiting
  • alanine aminotransferase increased
male:
  • headache
  • pulmonary mass
  • pulmonary oedema
  • pyrexia
  • fatigue
  • arthralgia
  • blood creatinine increased
  • c-reactive protein increased
  • disseminated intravascular coagulation
  • drug ineffective

Most common drug interactions by age *:

30-39:
  • injection site pain
40-49:
  • headache
  • fatigue
  • autoimmune neutropenia
  • neutrophil count decreased
  • blood testosterone decreased
  • burns third degree
  • desmoid tumour
  • pulmonary embolism
  • radiation injury
  • arthralgia
50-59:
  • pneumonia
  • pulmonary mass
  • pulmonary oedema
  • pyrexia
  • blood creatinine increased
  • c-reactive protein increased
  • cellulitis
  • disseminated intravascular coagulation
  • fall
  • hypertension
60+:
  • nausea
  • blood alkaline phosphatase increased
  • escherichia sepsis
  • pulmonary tuberculosis
  • uterine polyp
  • vomiting
  • insomnia
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood bilirubin increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Milk thistle?

Interactions between Methotrexate and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Milk thistle and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Milk thistle (milk thistle) is often used to treat liver disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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