Review: taking Methotrexate and Oxycontin together


Summary

Drug interactions are reported among people who take Methotrexate and Oxycontin together. This review analyzes the effectiveness and drug interactions between Methotrexate and Oxycontin. It is created by eHealthMe based on reports of 2,451 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,727 users)

Oxycontin

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycontin 58,599 users)

On Sep, 19, 2016

2,451 people who take Methotrexate, Oxycontin are studied.


Number of reports submitted per year:

Methotrexate and Oxycontin drug interactions.

Drug effectiveness over time:

Methotrexate:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Oxycontin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methotrexate:
  • female: 28.0% - (2 of 7 people)
  • male: 0.0% - (0 of 2 people)
Oxycontin:
  • female: 55.0% - (5 of 9 people)
  • male: 100.0% - (2 of 2 people)

Drug effectiveness by age:

Methotrexate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 25.0% - (1 of 4 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (1 of 2 people)
Oxycontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 60.0% - (3 of 5 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • hot flush
  • muscle twitching
  • withdrawal syndrome
  • vomiting
  • anaemia
  • pyrexia
  • malignant melanoma
  • nausea
  • pancytopenia
1 - 6 months:
  • sepsis
  • renal failure acute
  • cellulitis
  • endocarditis bacterial
  • febrile neutropenia
  • anaemia
  • squamous cell carcinoma
  • diarrhoea
  • fatigue
  • lung neoplasm
6 - 12 months:
  • pneumonia
  • pyrexia
  • squamous cell carcinoma
  • abdominal abscess
  • abdominal pain
  • adverse event
  • conjunctivitis
  • metastases to mouth
  • nodule
  • oral candidiasis
1 - 2 years:
  • diarrhoea
  • drug ineffective
  • fatigue
  • hypotension
  • nausea
  • pain
  • swelling
  • adverse event
  • anger
  • arthralgia
2 - 5 years:
  • pain
  • tremor
  • depression
  • drug dependence
  • abdominal pain
  • flatulence
  • mental disorder
  • suicidal ideation
  • arthralgia
  • drug withdrawal syndrome
5 - 10 years:
  • fatigue
  • back pain aggravated
  • depression
  • dry eyes
  • lack of regular bowel movements
  • libido decreased
  • neck pain
  • neck stiffness
  • weight gain
  • abdominal pain
10+ years:
  • bacterial pyelonephritis
  • anaemia
  • arthritis bacterial
  • back pain
  • blood glucose abnormal
  • bronchopneumonia
  • cauda equina syndrome
  • empyema
  • hyponatraemia
  • intervertebral disc disorder
not specified:
  • pain
  • arthralgia
  • nausea
  • drug ineffective
  • fatigue
  • dyspnoea
  • rheumatoid arthritis
  • headache
  • back pain
  • pyrexia

Most common drug interactions by gender *:

female:
  • pain
  • arthralgia
  • nausea
  • drug ineffective
  • fatigue
  • vomiting
  • back pain
  • dyspnoea
  • rheumatoid arthritis
  • pyrexia
male:
  • pain
  • arthralgia
  • weight decreased
  • depression
  • headache
  • drug ineffective
  • rheumatoid arthritis
  • back pain
  • pyrexia
  • oedema peripheral

Most common drug interactions by age *:

2-9:
  • febrile neutropenia
  • anaemia
  • mucosal inflammation
  • thrombocytopenia
  • hypokalaemia
  • leukopenia
  • neutropenia
  • stomatitis
  • hypertension
  • abdominal pain
10-19:
  • pyrexia
  • crohn's disease
  • decreased appetite
  • multi-organ failure
  • neutrophil count decreased
  • acute monocytic leukaemia
  • headache
  • myeloid leukaemia
  • pain
  • septic shock
20-29:
  • nausea
  • alopecia
  • cellulitis
  • endometriosis
  • pelvic inflammatory disease
  • vomiting
  • completed suicide
  • dyspnoea
  • neoplasm
  • white blood cell count decreased
30-39:
  • drug ineffective
  • diarrhoea
  • nausea
  • fatigue
  • vomiting
  • pain
  • arthralgia
  • hot flush
  • muscle twitching
  • withdrawal syndrome
40-49:
  • pain
  • rheumatoid arthritis
  • oedema peripheral
  • depression
  • pyrexia
  • weight decreased
  • headache
  • nausea
  • arthralgia
  • back pain
50-59:
  • pain
  • arthralgia
  • fatigue
  • nausea
  • headache
  • pyrexia
  • drug ineffective
  • vomiting
  • rheumatoid arthritis
  • dyspnoea
60+:
  • pain
  • arthralgia
  • fatigue
  • fall
  • back pain
  • oedema peripheral
  • drug ineffective
  • nausea
  • dyspnoea
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Oxycontin?

Can you answer these questions?

More questions for: Methotrexate, Oxycontin

You may be interested in these reviews

More reviews for: Methotrexate, Oxycontin

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Oxycontin (oxycodone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.