Review: taking Metoprolol tartrate and Depakote together


Summary

Drug interactions are reported among people who take Metoprolol tartrate and Depakote together. This review analyzes the effectiveness and drug interactions between Metoprolol tartrate and Depakote. It is created by eHealthMe based on reports of 510 people who take the same drugs from FDA and social media, and is updated regularly.

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Metoprolol Tartrate

Metoprolol tartrate has active ingredients of metoprolol tartrate. It is often used in high blood pressure. (latest outcomes from Metoprolol tartrate 38,699 users)

Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 30,545 users)

On Jul, 29, 2016

510 people who take Metoprolol Tartrate, Depakote are studied.


Number of reports submitted per year:

Metoprolol tartrate and Depakote drug interactions.

Drug effectiveness over time:

Metoprolol Tartrate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 16.0% - (1 of 6 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Depakote:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 25.0% - (1 of 4 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Metoprolol Tartrate:
  • female: 0.0% - (0 of 3 people)
  • male: 33.0% - (4 of 12 people)
Depakote:
  • female: 66.0% - (2 of 3 people)
  • male: 36.0% - (4 of 11 people)

Drug effectiveness by age:

Metoprolol Tartrate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 33.0% - (2 of 6 people)
Depakote:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 66.0% - (2 of 3 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 40.0% - (2 of 5 people)

Most common drug interactions over time *:

< 1 month:
  • agitation
  • memory impairment
  • pneumonia
  • polydipsia
  • rhabdomyolysis
  • specific gravity urine decreased
  • tubulointerstitial nephritis
  • confusion
  • delirium
  • gait disturbance
1 - 6 months:
  • anaphylactic shock
  • atrial fibrillation
  • gastrointestinal haemorrhage
  • haemoptysis
  • rectal haemorrhage
  • arthralgia
  • chest pain
  • depressive symptom
  • suicidal ideation
  • suicide attempt
6 - 12 months:
  • hypomagnesemia
  • pancreatitis haemorrhagic
  • pancreatitis necrotising
2 - 5 years:
  • hypertension
  • liver function test abnormal
  • type 2 diabetes mellitus
  • diabetic complication
  • diabetic ketoacidosis
  • dyslipidaemia
  • gastric ulcer
  • hyperglycaemia
  • loss of bladder control
  • loss of control of legs
5 - 10 years:
  • confusion
  • convulsion
  • coronary artery disease
  • diabetes mellitus
  • diabetic ketoacidosis
  • type 2 diabetes mellitus
  • arteriosclerosis coronary artery
  • back pain
  • cardiomegaly
  • cardiomyopathy
10+ years:
  • alopecia
  • benign hepatic neoplasm
  • dizziness
  • hiccups
  • hypomagnesemia
not specified:
  • hypertension
  • diabetes mellitus
  • dyspnoea
  • pain
  • type 2 diabetes mellitus
  • nausea
  • anxiety
  • back pain
  • headache
  • convulsion

Most common drug interactions by gender *:

female:
  • hypertension
  • pain
  • nausea
  • back pain
  • dyspnoea
  • anxiety
  • type 2 diabetes mellitus
  • abdominal pain
  • cardiac failure congestive
  • headache
male:
  • diabetes mellitus
  • hypertension
  • type 2 diabetes mellitus
  • dyspnoea
  • arthralgia
  • myocardial infarction
  • oedema peripheral
  • chest pain
  • diabetes mellitus inadequate control
  • suicidal ideation

Most common drug interactions by age *:

10-19:
  • gastric disorder
  • obesity
  • weight increased
  • dyspnoea
  • nausea
  • abdominal pain
  • back pain
  • diabetes mellitus
  • diabetes mellitus inadequate control
  • ear pain
20-29:
  • hypertension
  • weight increased
  • diabetes mellitus non-insulin-dependent
  • hyperglycaemia
  • prescribed overdose
  • blood cholesterol increased
  • diabetic ketoacidosis
  • nausea
  • blood triglycerides increased
  • cerebrovascular disorder
30-39:
  • diabetes mellitus
  • arthralgia
  • hypertension
  • anxiety
  • type 2 diabetes mellitus
  • agitation
  • pain in extremity
  • atrophy
  • blood cholesterol increased
  • dry skin
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • chest pain
  • diabetic neuropathy
  • diabetes mellitus inadequate control
  • back pain
  • blood cholesterol increased
  • convulsion
  • hypertension
  • arthralgia
50-59:
  • dyspnoea
  • pain
  • hypertension
  • tachycardia
  • cardiac failure congestive
  • hypotension
  • atelectasis
  • convulsion
  • pleural effusion
  • anxiety
60+:
  • atrial fibrillation
  • confusional state
  • nausea
  • tremor
  • asthenia
  • urinary tract infection
  • fall
  • hypertension
  • pneumonia
  • delirium

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Metoprolol tartrate (metoprolol tartrate) is often used to treat high blood pressure. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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