Review: taking Metoprolol tartrate and Simvastatin together


Summary

Drug interactions are reported among people who take Metoprolol tartrate and Simvastatin together. This review analyzes the effectiveness and drug interactions between Metoprolol tartrate and Simvastatin. It is created by eHealthMe based on reports of 11,218 people who take the same drugs from FDA and social media, and is updated regularly.

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Metoprolol Tartrate

Metoprolol tartrate has active ingredients of metoprolol tartrate. It is often used in high blood pressure. (latest outcomes from Metoprolol tartrate 40,569 users)

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 94,390 users)

On Aug, 19, 2016

11,218 people who take Metoprolol Tartrate, Simvastatin are studied.


Number of reports submitted per year:

Metoprolol tartrate and Simvastatin drug interactions.

Drug effectiveness over time:

Metoprolol Tartrate:
  • < 1 month: 8.0% - (1 of 12 people)
  • 1 - 6 months: 33.0% - (10 of 30 people)
  • 6 - 12 months: 37.0% - (9 of 24 people)
  • 1 - 2 years: 42.0% - (21 of 50 people)
  • 2 - 5 years: 47.0% - (32 of 68 people)
  • 5 - 10 years: 51.0% - (19 of 37 people)
  • 10+ years: 56.0% - (13 of 23 people)
  • not specified: 50.0% - (2 of 4 people)
Simvastatin:
  • < 1 month: 8.0% - (1 of 12 people)
  • 1 - 6 months: 26.0% - (7 of 26 people)
  • 6 - 12 months: 37.0% - (10 of 27 people)
  • 1 - 2 years: 42.0% - (14 of 33 people)
  • 2 - 5 years: 50.0% - (35 of 69 people)
  • 5 - 10 years: 57.0% - (24 of 42 people)
  • 10+ years: 63.0% - (14 of 22 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Metoprolol Tartrate:
  • female: 46.0% - (42 of 91 people)
  • male: 41.0% - (65 of 157 people)
Simvastatin:
  • female: 50.0% - (44 of 87 people)
  • male: 41.0% - (62 of 148 people)

Drug effectiveness by age:

Metoprolol Tartrate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 66.0% - (10 of 15 people)
  • 40-49: 35.0% - (7 of 20 people)
  • 50-59: 44.0% - (25 of 56 people)
  • 60+: 41.0% - (64 of 156 people)
Simvastatin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (7 of 14 people)
  • 40-49: 29.0% - (5 of 17 people)
  • 50-59: 57.0% - (31 of 54 people)
  • 60+: 42.0% - (63 of 150 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • rhabdomyolysis
  • pain
  • myalgia
  • renal failure acute
  • asthenia
  • blood creatinine increased
  • pneumonia
  • anxiety
  • cardiac arrest
1 - 6 months:
  • abortion missed
  • rhabdomyolysis
  • myalgia
  • nausea
  • acute myocardial infarction
  • cardiac failure congestive
  • fatigue
  • arthralgia
  • back pain
  • dizziness
6 - 12 months:
  • anxiety
  • pain
  • insomnia
  • nausea
  • asthenia
  • eczema
  • headache
  • tinnitus aggravated
  • tooth deposit
  • depression
1 - 2 years:
  • rhabdomyolysis
  • myocardial infarction
  • dizziness
  • dehydration
  • anxiety
  • chest pain
  • asthenia
  • dyspnoea
  • fatigue
  • renal failure acute
2 - 5 years:
  • myocardial infarction
  • rhabdomyolysis
  • dizziness
  • blood pressure increased
  • anxiety
  • myalgia
  • nausea
  • palpitations
  • headache
  • cough
5 - 10 years:
  • atrial fibrillation/flutter
  • central sleep apnea
  • myocardial infarction
  • rectal haemorrhage
  • high blood pressure
  • atrial fibrillation
  • dyspnoea
  • escherichia sepsis
  • lobar pneumonia
  • nausea
10+ years:
  • coma
  • diabetic ketoacidosis
  • multi-organ disorder
  • pneumonia
  • acute myocardial infarction
  • escherichia sepsis
  • myocardial infarction
  • autoimmune hepatitis
  • cardiac disorder
  • cholangitis sclerosing
not specified:
  • pain
  • dyspnoea
  • nausea
  • fatigue
  • myocardial infarction
  • dizziness
  • anxiety
  • chest pain
  • asthenia
  • anaemia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • dyspnoea
  • myocardial infarction
  • asthenia
  • anaemia
  • chest pain
  • dizziness
  • fall
male:
  • pain
  • dyspnoea
  • myocardial infarction
  • anxiety
  • nausea
  • dizziness
  • fatigue
  • chest pain
  • cardiac failure congestive
  • renal failure

Most common drug interactions by age *:

0-1:
  • drug ineffective
  • viral infection
2-9:
  • accidental exposure
10-19:
  • hypovolaemia
  • abdominal pain
  • abdominal pain upper
  • aggression
  • colitis
  • confusional state
  • death
  • depression
  • diabetes mellitus
  • diabetic hyperosmolar coma
20-29:
  • asthenia
  • dehydration
  • abdominal pain
  • hypotension
  • nephrogenic systemic fibrosis
  • pain
  • cardiomegaly
  • chest pain
  • convulsion
  • depression
30-39:
  • myocardial infarction
  • chest pain
  • pain
  • hypertension
  • blood cholesterol increased
  • fatigue
  • gastrooesophageal reflux disease
  • dyspepsia
  • oedema peripheral
  • nausea
40-49:
  • pain
  • nausea
  • anxiety
  • myocardial infarction
  • depression
  • fatigue
  • chest pain
  • injury
  • dyspnoea
  • back pain
50-59:
  • myocardial infarction
  • pain
  • dyspnoea
  • nausea
  • anxiety
  • chest pain
  • back pain
  • cardiac failure congestive
  • asthenia
  • injury
60+:
  • pain
  • dyspnoea
  • fatigue
  • nausea
  • dizziness
  • myocardial infarction
  • asthenia
  • atrial fibrillation
  • anaemia
  • cardiac failure congestive

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Metoprolol tartrate (metoprolol tartrate) is often used to treat high blood pressure. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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