Review: taking Milk thistle and Metformin together


Summary

Drug interactions are reported among people who take Milk thistle and Metformin together. This review analyzes the effectiveness and drug interactions between Milk thistle and Metformin. It is created by eHealthMe based on reports of 168 people who take the same drugs from FDA and social media, and is updated regularly.

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Milk Thistle

Milk thistle has active ingredients of milk thistle. It is often used in liver disorder. (latest outcomes from Milk thistle 1,490 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

On Sep, 16, 2016

168 people who take Milk Thistle, Metformin are studied.


Number of reports submitted per year:

Milk thistle and Metformin drug interactions.

Drug effectiveness over time:

Milk Thistle:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Metformin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Milk Thistle:
  • female: 0.0% - (0 of 1 people)
  • male: 50.0% - (1 of 2 people)
Metformin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 2 people)

Drug effectiveness by age:

Milk Thistle:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 100.0% - (1 of 1 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • abdominal discomfort
  • diarrhoea
  • dyspepsia
  • hypertensive crisis
  • pyrexia
  • cerebral haemorrhage
  • deep vein thrombosis
  • diplopia
  • influenza
1 - 6 months:
  • myalgia
  • neutropenia
  • pyrexia
  • cerebrovascular accident
  • deep vein thrombosis
  • depressed level of consciousness
6 - 12 months:
  • onychomadesis
1 - 2 years:
  • abasia
  • dysstasia
  • myalgia
  • peripheral swelling
  • product odour abnormal
2 - 5 years:
  • sepsis
  • diarrhea
  • loss of hair
5 - 10 years:
  • tinnitus aggravated
  • vertigo
  • cerebral haemorrhage
  • diarrhea
  • diplopia
  • loss of hair
  • metastases to central nervous system
  • muscular weakness
  • pyrexia
  • thrombocytopenia
10+ years:
  • sepsis
not specified:
  • fatigue
  • nausea
  • diarrhoea
  • asthenia
  • insomnia
  • pruritus
  • decreased appetite
  • drug ineffective
  • anaemia
  • pain

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • diarrhoea
  • myalgia
  • drug ineffective
  • insomnia
  • foot fracture
  • pain
  • pruritus
  • asthenia
male:
  • fatigue
  • asthenia
  • decreased appetite
  • anaemia
  • diarrhoea
  • abdominal tenderness
  • febrile neutropenia
  • hepatic enzyme increased
  • tonsillitis
  • white blood cell count decreased

Most common drug interactions by age *:

30-39:
  • hepatic enzyme increased
  • asthenia
  • blood pressure decreased
  • dyspnoea
  • generalised erythema
  • infusion related reaction
  • tachycardia
  • thyroid cancer
40-49:
  • androgen deficiency
  • calcium deficiency
  • emotional distress
  • fatigue
  • foot fracture
  • neuropathic arthropathy
  • osteoarthritis
  • osteoporosis
  • ulna fracture
  • upper limb fracture
50-59:
  • diarrhoea
  • pain
  • drug ineffective
  • fatigue
  • nausea
  • abasia
  • abdominal discomfort
  • anxiety
  • blood glucose increased
  • cellulitis
60+:
  • fatigue
  • asthenia
  • diarrhoea
  • insomnia
  • nausea
  • anaemia
  • muscular weakness
  • abdominal tenderness
  • decreased appetite
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Milk thistle (milk thistle) is often used to treat liver disorder. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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