Review: taking Milk thistle and Metformin together


Summary

Drug interactions are reported among people who take Milk thistle and Metformin together. This review analyzes the effectiveness and drug interactions between Milk thistle and Metformin. It is created by eHealthMe based on reports of 86 people who take the same drugs from FDA and social media, and is updated regularly.

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Milk Thistle

Milk thistle has active ingredients of milk thistle. It is often used in liver disorder. (latest outcomes from Milk thistle 838 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

On Aug, 19, 2016

86 people who take Milk Thistle, Metformin are studied.


Number of reports submitted per year:

Milk thistle and Metformin drug interactions.

Drug effectiveness over time:

Milk Thistle:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Metformin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Milk Thistle:
  • female: 0.0% - (0 of 1 people)
  • male: 50.0% - (1 of 2 people)
Metformin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 2 people)

Drug effectiveness by age:

Milk Thistle:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 100.0% - (1 of 1 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • cerebral haemorrhage
  • diplopia
  • metastases to central nervous system
  • muscular weakness
  • thrombocytopenia
1 - 6 months:
  • cerebrovascular accident
  • depressed level of consciousness
2 - 5 years:
  • diarrhea
  • loss of hair
  • sepsis
5 - 10 years:
  • tinnitus aggravated
  • cerebral haemorrhage
  • diarrhea
  • diplopia
  • loss of hair
  • metastases to central nervous system
  • muscular weakness
  • thrombocytopenia
10+ years:
  • sepsis
not specified:
  • fatigue
  • nausea
  • asthenia
  • pruritus
  • diarrhoea
  • abdominal tenderness
  • anaemia
  • decreased appetite
  • febrile neutropenia
  • flushing

Most common drug interactions by gender *:

female:
  • nausea
  • emotional distress
  • fatigue
  • flushing
  • foot fracture
  • osteoporosis
  • vitamin d deficiency
  • androgen deficiency
  • arthritis
  • calcium deficiency
male:
  • abdominal tenderness
  • fatigue
  • febrile neutropenia
  • tonsillitis
  • asthenia
  • decreased appetite
  • dysphonia
  • haemoglobin decreased
  • odynophagia
  • thrombocytopenia

Most common drug interactions by age *:

30-39:
  • thyroid cancer
40-49:
  • androgen deficiency
  • calcium deficiency
  • emotional distress
  • fatigue
  • foot fracture
  • neuropathic arthropathy
  • osteoarthritis
  • osteoporosis
  • ulna fracture
  • upper limb fracture
50-59:
  • diarrhoea
  • fatigue
  • dehydration
  • hypotension
  • nausea
  • pain
  • pruritus
  • somnolence
  • abdominal distension
  • adverse event
60+:
  • abdominal tenderness
  • febrile neutropenia
  • tonsillitis
  • anaemia
  • dysphonia
  • odynophagia
  • thrombocytopenia
  • asthenia
  • cerebral haemorrhage
  • chills

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Milk thistle (milk thistle) is often used to treat liver disorder. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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