Review: taking Mirtazapine and Cymbalta together


Summary

Drug interactions are reported among people who take Mirtazapine and Cymbalta together. This review analyzes the effectiveness and drug interactions between Mirtazapine and Cymbalta. It is created by eHealthMe based on reports of 1,855 people who take the same drugs from FDA and social media, and is updated regularly.

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Mirtazapine

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from Mirtazapine 27,373 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 89,411 users)

On Sep, 16, 2016

1,855 people who take Mirtazapine, Cymbalta are studied.


Number of reports submitted per year:

Mirtazapine and Cymbalta drug interactions.

Drug effectiveness over time:

Mirtazapine:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 40.0% - (4 of 10 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 28.0% - (2 of 7 people)
  • 5 - 10 years: 33.0% - (3 of 9 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 27.0% - (3 of 11 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 50.0% - (4 of 8 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 42.0% - (3 of 7 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Mirtazapine:
  • female: 34.0% - (8 of 23 people)
  • male: 35.0% - (7 of 20 people)
Cymbalta:
  • female: 32.0% - (8 of 25 people)
  • male: 35.0% - (7 of 20 people)

Drug effectiveness by age:

Mirtazapine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 33.0% - (3 of 9 people)
  • 40-49: 44.0% - (4 of 9 people)
  • 50-59: 25.0% - (2 of 8 people)
  • 60+: 33.0% - (4 of 12 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 60.0% - (3 of 5 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 22.0% - (2 of 9 people)
  • 50-59: 37.0% - (3 of 8 people)
  • 60+: 41.0% - (5 of 12 people)

Most common drug interactions over time *:

< 1 month:
  • palpitations
  • nausea
  • diarrhoea
  • loss of consciousness
  • sinus tachycardia
  • hyperhidrosis
  • drug withdrawal syndrome
  • hepatic function abnormal
  • weight decreased
  • hypersensitivity
1 - 6 months:
  • anxiety
  • depression
  • nausea
  • vomiting
  • somnolence
  • weight decreased
  • agitation
  • completed suicide
  • headache
  • renal impairment
6 - 12 months:
  • anxiety
  • depression
  • dizziness
  • drug exposure during pregnancy
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • nausea
  • renal impairment
  • syncope
  • decreased appetite
  • depressed mood
1 - 2 years:
  • type 2 diabetes mellitus
  • coronary artery disease
  • movement disorder
  • multiple sclerosis
  • tardive dyskinesia
  • stomach pain
  • urinary retention
  • pain
  • convulsion
  • dizziness
2 - 5 years:
  • muscle pain
  • rash
  • renal impairment
  • abortion spontaneous
  • hypertension
  • pregnancy
  • white blood cell count abnormal
  • abnormal dreams
  • anxiety
  • arrhythmia
5 - 10 years:
  • dystonia
  • ear injury
  • foetal methotrexate syndrome
  • hives
  • skin haemorrhage
  • tardive dyskinesia
  • umbilical haemorrhage
  • chest discomfort
  • nausea
  • dysfunctional uterine bleeding
10+ years:
  • tremor
  • depression
  • fatigue - chronic
  • fatigue aggravated
  • itching in the groin
  • itching scar
  • palpitations
not specified:
  • depression
  • drug ineffective
  • anxiety
  • pain
  • nausea
  • weight increased
  • type 2 diabetes mellitus
  • fall
  • dizziness
  • fatigue

Most common drug interactions by gender *:

female:
  • nausea
  • depression
  • type 2 diabetes mellitus
  • anxiety
  • pain
  • fall
  • drug ineffective
  • diarrhoea
  • weight increased
  • vomiting
male:
  • drug ineffective
  • anxiety
  • depression
  • pain
  • suicidal ideation
  • liver function test abnormal
  • insomnia
  • dizziness
  • weight decreased
  • completed suicide

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • drug withdrawal syndrome neonatal
  • foetal exposure during pregnancy
  • gallbladder operation
  • irritability
  • parkinsonism
  • restlessness
  • sensation of foreign body
  • type 2 diabetes mellitus
  • ventricular septal defect
10-19:
  • tachycardia
  • agitation
  • somnolence
  • mydriasis
  • aggression
  • anger
  • constipation
  • deafness
  • disturbance in attention
  • drug ineffective
20-29:
  • nausea
  • diarrhoea
  • weight decreased
  • sinus tachycardia
  • general physical health deterioration
  • drug intolerance
  • hyperhidrosis
  • palpitations
  • dizziness postural
  • dyspnoea at rest
30-39:
  • weight increased
  • loss of consciousness
  • diabetes mellitus
  • abdominal pain
  • completed suicide
  • diabetes mellitus inadequate control
  • nausea
  • suicidal ideation
  • type 2 diabetes mellitus
  • back pain
40-49:
  • type 2 diabetes mellitus
  • depression
  • metabolic syndrome
  • hypothyroidism
  • anxiety
  • liver function test abnormal
  • neuropathy peripheral
  • pain
  • weight increased
  • somnolence
50-59:
  • depression
  • drug ineffective
  • type 2 diabetes mellitus
  • weight increased
  • nausea
  • diabetes mellitus
  • fall
  • fatigue
  • blood cholesterol increased
  • loss of consciousness
60+:
  • nausea
  • anxiety
  • drug ineffective
  • tremor
  • dizziness
  • fall
  • depression
  • dysphagia
  • weight decreased
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Mirtazapine (mirtazapine) is often used to treat depression. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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