Review: taking Mirtazapine and Cymbalta together


Summary

Drug interactions are reported among people who take Mirtazapine and Cymbalta together. This review analyzes the effectiveness and drug interactions between Mirtazapine and Cymbalta. It is created by eHealthMe based on reports of 1,439 people who take the same drugs from FDA and social media, and is updated regularly.

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Mirtazapine

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from Mirtazapine 20,206 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 56,552 users)

On Aug, 23, 2016

1,439 people who take Mirtazapine, Cymbalta are studied.


Number of reports submitted per year:

Mirtazapine and Cymbalta drug interactions.

Drug effectiveness over time:

Mirtazapine:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 40.0% - (4 of 10 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 28.0% - (2 of 7 people)
  • 5 - 10 years: 33.0% - (3 of 9 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 27.0% - (3 of 11 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 50.0% - (4 of 8 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 42.0% - (3 of 7 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Mirtazapine:
  • female: 34.0% - (8 of 23 people)
  • male: 35.0% - (7 of 20 people)
Cymbalta:
  • female: 32.0% - (8 of 25 people)
  • male: 35.0% - (7 of 20 people)

Drug effectiveness by age:

Mirtazapine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 33.0% - (3 of 9 people)
  • 40-49: 44.0% - (4 of 9 people)
  • 50-59: 25.0% - (2 of 8 people)
  • 60+: 33.0% - (4 of 12 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 60.0% - (3 of 5 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 22.0% - (2 of 9 people)
  • 50-59: 37.0% - (3 of 8 people)
  • 60+: 41.0% - (5 of 12 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • diarrhoea
  • loss of consciousness
  • sinus tachycardia
  • palpitations
  • hepatic function abnormal
  • weight decreased
  • drug withdrawal syndrome
  • hypersensitivity
  • renal impairment
1 - 6 months:
  • anxiety
  • depression
  • nausea
  • vomiting
  • weight decreased
  • agitation
  • completed suicide
  • renal impairment
  • somnolence
  • thrombocytopenia
6 - 12 months:
  • anxiety
  • depression
  • dizziness
  • drug exposure during pregnancy
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • nausea
  • renal impairment
  • syncope
  • decreased appetite
  • depressed mood
1 - 2 years:
  • type 2 diabetes mellitus
  • coronary artery disease
  • movement disorder
  • multiple sclerosis
  • tardive dyskinesia
  • stomach pain
  • urinary retention
  • convulsion
  • obesity
  • acute respiratory failure
2 - 5 years:
  • muscle pain
  • rash
  • renal impairment
  • abortion spontaneous
  • hypertension
  • pregnancy
  • anxiety
  • autoimmune hepatitis
  • blood cholesterol increased
  • blood triglycerides increased
5 - 10 years:
  • dystonia
  • ear injury
  • foetal methotrexate syndrome
  • hives
  • skin haemorrhage
  • tardive dyskinesia
  • umbilical haemorrhage
  • chest discomfort
  • nausea
  • dysfunctional uterine bleeding
10+ years:
  • tremor
  • depression
  • fatigue - chronic
  • fatigue aggravated
  • itching in the groin
  • itching scar
  • palpitations
not specified:
  • depression
  • drug ineffective
  • type 2 diabetes mellitus
  • anxiety
  • pain
  • weight increased
  • nausea
  • fall
  • diarrhoea
  • fatigue

Most common drug interactions by gender *:

female:
  • nausea
  • type 2 diabetes mellitus
  • depression
  • anxiety
  • diarrhoea
  • pain
  • fall
  • drug ineffective
  • weight increased
  • neuropathy peripheral
male:
  • drug ineffective
  • depression
  • liver function test abnormal
  • anxiety
  • insomnia
  • metabolic syndrome
  • suicidal ideation
  • hypothyroidism
  • suicide attempt
  • pain

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • gallbladder operation
  • parkinsonism
  • sensation of foreign body
  • type 2 diabetes mellitus
10-19:
  • tachycardia
  • agitation
  • somnolence
  • mydriasis
  • aggression
  • anger
  • constipation
  • deafness
  • disturbance in attention
  • drug ineffective
20-29:
  • diarrhoea
  • nausea
  • weight decreased
  • sinus tachycardia
  • general physical health deterioration
  • drug intolerance
  • hyperhidrosis
  • dizziness postural
  • dyspnoea at rest
  • hypophagia
30-39:
  • weight increased
  • diabetes mellitus
  • loss of consciousness
  • abdominal pain
  • completed suicide
  • diabetes mellitus inadequate control
  • type 2 diabetes mellitus
  • blood glucose increased
  • cellulitis
  • hidradenitis
40-49:
  • type 2 diabetes mellitus
  • metabolic syndrome
  • hypothyroidism
  • liver function test abnormal
  • anxiety
  • depression
  • neuropathy peripheral
  • pain
  • weight increased
  • fatigue
50-59:
  • type 2 diabetes mellitus
  • drug ineffective
  • diabetes mellitus
  • weight increased
  • blood cholesterol increased
  • depression
  • loss of consciousness
  • fall
  • suicide attempt
  • oedema peripheral
60+:
  • nausea
  • tremor
  • anxiety
  • drug ineffective
  • depression
  • diarrhoea
  • decreased appetite
  • insomnia
  • arthralgia
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Mirtazapine (mirtazapine) is often used to treat depression. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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