Review: taking Mirtazapine and Tramadol together


Summary

Drug interactions are reported among people who take Mirtazapine and Tramadol together. This review analyzes the effectiveness and drug interactions between Mirtazapine and Tramadol. It is created by eHealthMe based on reports of 1,822 people who take the same drugs from FDA and social media, and is updated regularly.

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Mirtazapine

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from Mirtazapine 27,371 users)

Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 73,712 users)

On Sep, 20, 2016

1,822 people who take Mirtazapine, Tramadol are studied.


Number of reports submitted per year:

Mirtazapine and Tramadol drug interactions.

Drug effectiveness over time:

Mirtazapine:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 33.0% - (3 of 9 people)
  • 6 - 12 months: 42.0% - (3 of 7 people)
  • 1 - 2 years: 66.0% - (4 of 6 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 100.0% - (1 of 1 people)
Tramadol:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 66.0% - (4 of 6 people)
  • 6 - 12 months: 40.0% - (2 of 5 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 14.0% - (1 of 7 people)
  • 5 - 10 years: 20.0% - (1 of 5 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Mirtazapine:
  • female: 40.0% - (9 of 22 people)
  • male: 42.0% - (6 of 14 people)
Tramadol:
  • female: 21.0% - (5 of 23 people)
  • male: 40.0% - (6 of 15 people)

Drug effectiveness by age:

Mirtazapine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 66.0% - (6 of 9 people)
  • 40-49: 42.0% - (3 of 7 people)
  • 50-59: 40.0% - (2 of 5 people)
  • 60+: 27.0% - (3 of 11 people)
Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 40.0% - (4 of 10 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • agitation
  • fatigue
  • serotonin syndrome
  • diarrhoea
  • tachycardia
  • depression
  • hyperhidrosis
  • suicidal ideation
  • confusional state
  • dizziness
1 - 6 months:
  • suicidal ideation
  • depression
  • serotonin syndrome
  • vomiting
  • dizziness
  • fatigue
  • cogwheel rigidity
  • headache
  • anxiety
  • delirium
6 - 12 months:
  • convulsion
  • loss of consciousness
  • rheumatoid arthritis
  • serotonin syndrome
  • sweating - excessive
  • discomfort
  • anxiety
  • asthenia
  • cluttering
  • confusional state
1 - 2 years:
  • lethargy
  • suicidal ideation
  • crying
  • depression
  • hostility
  • mood altered
  • thinking abnormal
  • decreased appetite
  • affective disorder
  • antisocial personality disorder
2 - 5 years:
  • suicidal ideation
  • anxiety
  • dizziness
  • serotonin syndrome
  • depression
  • paraesthesia
  • arthralgia
  • incontinence
  • urinary retention
  • cogwheel rigidity
5 - 10 years:
  • abdominal distension
  • constipation
  • dyspepsia
  • faeces hard
  • gastrooesophageal reflux disease
  • haemorrhoids
  • oedema
  • rectal haemorrhage
  • depression
  • suicidal ideation
10+ years:
  • acute sinusitis
  • alcohol use
  • arthralgia
  • cardiac failure congestive
  • confusional state
  • convulsion
  • dehydration
  • diabetes mellitus
  • diabetic ketoacidosis
  • diarrhoea
not specified:
  • pain
  • anxiety
  • nausea
  • headache
  • fatigue
  • dyspnoea
  • fall
  • asthenia
  • arthralgia
  • dizziness

Most common drug interactions by gender *:

female:
  • headache
  • pain
  • anxiety
  • fatigue
  • dizziness
  • asthenia
  • dyspnoea
  • arthralgia
  • depression
  • nausea
male:
  • anxiety
  • pain
  • dyspnoea
  • fatigue
  • nausea
  • vomiting
  • fall
  • weight decreased
  • confusional state
  • headache

Most common drug interactions by age *:

0-1:
  • cardio-respiratory arrest
  • convulsion
  • coma
  • apnoea
  • cleft lip and palate
  • maternal exposure during pregnancy
  • accidental drug intake by child
  • accidental exposure
  • blood cholesterol increased
  • blood triglycerides increased
2-9:
  • emotional disorder
  • tardive dyskinesia
  • alopecia
  • blindness
  • hypersensitivity
  • internal injury
  • mucous membrane disorder
  • nail disorder
  • oral disorder
  • pigmentation disorder
10-19:
  • constipation
  • depression
  • dyspepsia
  • haemorrhoids
  • suicidal ideation
  • abdominal distension
  • faeces hard
  • gastrooesophageal reflux disease
  • oedema
  • rectal haemorrhage
20-29:
  • serotonin syndrome
  • headache
  • completed suicide
  • hyperhidrosis
  • suicidal ideation
  • depression
  • anxiety
  • dizziness
  • multiple drug overdose
  • convulsion
30-39:
  • headache
  • dizziness
  • asthenia
  • tremor
  • paraesthesia
  • sleep disorder
  • visual impairment
  • contusion
  • convulsion
  • fatigue
40-49:
  • headache
  • fatigue
  • nausea
  • pain
  • depression
  • dyspnoea
  • drug ineffective
  • anxiety
  • asthenia
  • insomnia
50-59:
  • anxiety
  • pain
  • fall
  • diarrhoea
  • headache
  • dizziness
  • hypotension
  • back pain
  • nausea
  • fatigue
60+:
  • nausea
  • anxiety
  • dyspnoea
  • fall
  • pain
  • vomiting
  • confusional state
  • back pain
  • fatigue
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Mirtazapine (mirtazapine) is often used to treat depression. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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