Review: taking Morphine sulfate and Tramadol together


Summary

Drug interactions are reported among people who take Morphine sulfate and Tramadol together. This review analyzes the effectiveness and drug interactions between Morphine sulfate and Tramadol. It is created by eHealthMe based on reports of 2,336 people who take the same drugs from FDA and social media, and is updated regularly.

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Morphine Sulfate

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine sulfate 18,241 users)

Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 42,204 users)

On Jul, 24, 2016

2,336 people who take Morphine Sulfate, Tramadol are studied.


Number of reports submitted per year:

Morphine sulfate and Tramadol drug interactions.

Drug effectiveness over time:

Morphine Sulfate:
  • < 1 month: 55.0% - (5 of 9 people)
  • 1 - 6 months: 42.0% - (3 of 7 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 4 people)
  • not specified: 0.0% - (0 of 1 people)
Tramadol:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 18.0% - (2 of 11 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 3 people)

Drug effectiveness by gender:

Morphine Sulfate:
  • female: 34.0% - (9 of 26 people)
  • male: 38.0% - (5 of 13 people)
Tramadol:
  • female: 16.0% - (4 of 25 people)
  • male: 15.0% - (2 of 13 people)

Drug effectiveness by age:

Morphine Sulfate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 42.0% - (3 of 7 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 53.0% - (7 of 13 people)
  • 50-59: 14.0% - (1 of 7 people)
  • 60+: 0.0% - (0 of 3 people)
Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 6 people)
  • 30-39: 37.0% - (3 of 8 people)
  • 40-49: 16.0% - (2 of 12 people)
  • 50-59: 12.0% - (1 of 8 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • hypokalaemia
  • diarrhoea
  • liver carcinoma ruptured
  • aspartate aminotransferase increased
  • abdominal pain
  • hepatic failure
  • confusional state
  • pneumonia
  • somnolence
  • respiratory arrest
1 - 6 months:
  • dyspnoea
  • vomiting
  • pneumonia
  • respiratory distress
  • haemorrhage
  • mental status changes
  • pyrexia
  • diarrhoea
  • dysphagia
  • escherichia infection
6 - 12 months:
  • rhabdomyolysis
  • back pain
  • bone pain
  • dyspnoea
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • liver function test abnormal
  • memory impairment
  • mental impairment
  • migraine
  • pain - elbow
1 - 2 years:
  • somnolence
  • alcoholism
  • aortic valve incompetence
  • asthenia
  • back pain
  • cerebrovascular accident
  • chest pain
  • costochondritis
  • depression suicidal
  • dyspnoea
2 - 5 years:
  • constipation
  • delusion
  • intentional self-injury
  • abdominal pain
  • abdominal pain upper
  • cholecystitis
  • cholecystitis chronic
  • dyspnoea
  • fatigue
  • high blood pressure
5 - 10 years:
  • bone pain
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • high blood pressure
  • memory impairment
  • constipation aggravated
  • depression
  • mood swings
  • numbness and tingling
  • pain in limb
  • paranoia aggravated
10+ years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • hypotension
  • sweating - excessive
not specified:
  • pain
  • nausea
  • anxiety
  • dyspnoea
  • headache
  • fatigue
  • back pain
  • asthenia
  • fall
  • anaemia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • dyspnoea
  • anaemia
  • fatigue
  • anxiety
  • headache
  • asthenia
  • back pain
  • fall
male:
  • abdominal pain
  • anxiety
  • pain
  • dyspnoea
  • diarrhoea
  • nausea
  • cardio-respiratory arrest
  • vomiting
  • pneumonia
  • somnolence

Most common drug interactions by age *:

0-1:
  • crying
  • hyperaesthesia
  • distress
  • drug exposure during pregnancy
  • sudden death
2-9:
  • sepsis
  • arthralgia
  • bone pain
  • respiratory failure
  • tumour lysis syndrome
  • pneumonia
  • renal failure
  • abdominal pain
  • somnolence
  • agitation
10-19:
  • anal fistula
  • anal abscess
  • cholecystitis chronic
  • cyst
  • nausea
  • abdominal pain
  • gallbladder disorder
  • pain
  • pancreatitis
  • pyrexia
20-29:
  • anxiety
  • headache
  • dyspnoea
  • chills
  • pneumonia
  • amnesia
  • pain
  • dizziness
  • dry mouth
  • dysarthria
30-39:
  • headache
  • nausea
  • depression
  • drug withdrawal syndrome
  • chest pain
  • abdominal pain
  • pain
  • anxiety
  • arthralgia
  • dyspnoea
40-49:
  • diarrhoea
  • anxiety
  • pain
  • abdominal pain
  • hypokalaemia
  • nausea
  • aspartate aminotransferase increased
  • liver carcinoma ruptured
  • fatigue
  • hypoaesthesia
50-59:
  • nausea
  • arthralgia
  • asthenia
  • bone disorder
  • dyspnoea
  • anaemia
  • pain in extremity
  • diarrhoea
  • back pain
  • osteoarthritis
60+:
  • dyspnoea
  • pain
  • fall
  • anaemia
  • fatigue
  • weight decreased
  • asthenia
  • confusional state
  • nausea
  • osteoarthritis

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Morphine sulfate (morphine sulfate) is often used to treat pain. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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