Review: taking Morphine and Alprazolam together


Summary

Drug interactions are reported among people who take Morphine and Alprazolam together. This review analyzes the effectiveness and drug interactions between Morphine and Alprazolam. It is created by eHealthMe based on reports of 4,895 people who take the same drugs from FDA and social media, and is updated regularly.

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Morphine

Morphine has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine 55,422 users)

Alprazolam

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Alprazolam 39,657 users)

On Aug, 19, 2016

4,895 people who take Morphine, Alprazolam are studied.


Number of reports submitted per year:

Morphine and Alprazolam drug interactions.

Drug effectiveness over time:

Morphine:
  • < 1 month: 15.0% - (2 of 13 people)
  • 1 - 6 months: 42.0% - (3 of 7 people)
  • 6 - 12 months: 25.0% - (2 of 8 people)
  • 1 - 2 years: 33.0% - (3 of 9 people)
  • 2 - 5 years: 42.0% - (8 of 19 people)
  • 5 - 10 years: 33.0% - (3 of 9 people)
  • 10+ years: 0.0% - (0 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Alprazolam:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 50.0% - (3 of 6 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 46.0% - (7 of 15 people)
  • 2 - 5 years: 47.0% - (10 of 21 people)
  • 5 - 10 years: 69.0% - (9 of 13 people)
  • 10+ years: 100.0% - (11 of 11 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Morphine:
  • female: 35.0% - (16 of 45 people)
  • male: 20.0% - (5 of 24 people)
Alprazolam:
  • female: 64.0% - (31 of 48 people)
  • male: 38.0% - (10 of 26 people)

Drug effectiveness by age:

Morphine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 35.0% - (6 of 17 people)
  • 40-49: 26.0% - (6 of 23 people)
  • 50-59: 22.0% - (4 of 18 people)
  • 60+: 75.0% - (3 of 4 people)
Alprazolam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 66.0% - (4 of 6 people)
  • 30-39: 40.0% - (8 of 20 people)
  • 40-49: 54.0% - (13 of 24 people)
  • 50-59: 63.0% - (12 of 19 people)
  • 60+: 75.0% - (3 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • pain
  • renal failure
  • anaemia
  • dehydration
  • abdominal pain
  • diarrhoea
  • nausea
  • headache
  • asthenia
1 - 6 months:
  • asthenia
  • hypotension
  • anaemia
  • confusional state
  • pain in extremity
  • dehydration
  • dyspnoea
  • pleural effusion
  • fatigue
  • renal failure acute
6 - 12 months:
  • somnolence
  • hypotension
  • lethargy
  • nephrolithiasis
  • dizziness
  • anxiety
  • dyspnoea
  • unresponsive to stimuli
  • asthenia
  • bradyarrhythmia
1 - 2 years:
  • pain
  • anxiety
  • anaemia
  • apnoea
  • atrial septal defect
  • drug exposure during pregnancy
  • foetal distress syndrome
  • pulmonary hypertension
  • respiratory distress
  • ventricular septal defect
2 - 5 years:
  • drug dependence
  • constipation
  • fatigue
  • nausea
  • agitation
  • back pain
  • multiple drug overdose
  • abdominal pain
  • ankle fracture
  • arthralgia
5 - 10 years:
  • dehydration
  • death
  • fatigue
  • respiratory failure
  • chest discomfort
  • heart rate decreased
  • memory impairment
  • affect lability
  • anaemia
  • anger
10+ years:
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • shoulder blade pain
  • sweating
  • swelling of the ankles - feet - legs
  • chronic pain
  • inability to crawl
  • pacemaker
  • uti - chronic or recurrent
  • weight gain
  • weight loss
not specified:
  • pain
  • anxiety
  • nausea
  • back pain
  • dyspnoea
  • pyrexia
  • vomiting
  • injury
  • fall
  • fatigue

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • back pain
  • fall
  • vomiting
  • pain in extremity
  • injury
  • pyrexia
male:
  • anxiety
  • pain
  • nausea
  • drug abuse
  • back pain
  • chest pain
  • asthenia
  • dyspnoea
  • pyrexia
  • fatigue

Most common drug interactions by age *:

0-1:
  • orthostatic hypotension
  • feeding disorder neonatal
  • hypoglycaemia
  • respiratory distress
  • agitation
  • anorectal disorder
  • developmental delay
  • drug exposure during pregnancy
  • feeding problem in newborn
  • gastric disorder
2-9:
  • convulsion
  • death
  • febrile bone marrow aplasia
  • mucosal inflammation
  • accidental exposure
  • confusional state
  • febrile neutropenia
  • haemoglobin decreased
  • infection
  • lymphopenia
10-19:
  • cardio-respiratory arrest
  • respiratory arrest
  • cardiac arrest
  • completed suicide
  • drug abuser
  • drug abuse
  • pain
  • multiple drug overdose
  • substance abuse
  • death
20-29:
  • drug abuse
  • completed suicide
  • pain
  • respiratory arrest
  • anxiety
  • death
  • nausea
  • drug dependence
  • poisoning
  • pulmonary embolism
30-39:
  • drug abuse
  • nausea
  • pain
  • anxiety
  • back pain
  • pain in extremity
  • cardio-respiratory arrest
  • vomiting
  • dyspnoea
  • fatigue
40-49:
  • anxiety
  • pain
  • nausea
  • dyspnoea
  • back pain
  • constipation
  • depression
  • osteonecrosis of jaw
  • chest pain
  • fatigue
50-59:
  • pain
  • anxiety
  • pyrexia
  • nausea
  • hypoaesthesia
  • injury
  • back pain
  • dyspnoea
  • vomiting
  • arthralgia
60+:
  • pain
  • anxiety
  • asthenia
  • nausea
  • anaemia
  • fall
  • vomiting
  • dehydration
  • back pain
  • injury

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Morphine (morphine sulfate) is often used to treat pain. Alprazolam (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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