Review: taking Naproxen and Omeprazole together


Summary

Drug interactions are reported among people who take Naproxen and Omeprazole together. This review analyzes the effectiveness and drug interactions between Naproxen and Omeprazole. It is created by eHealthMe based on reports of 6,135 people who take the same drugs from FDA and social media, and is updated regularly.

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Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 36,950 users)

Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Omeprazole 154,416 users)

On Sep, 09, 2016

6,135 people who take Naproxen, Omeprazole are studied.


Number of reports submitted per year:

Naproxen and Omeprazole drug interactions.

Drug effectiveness over time:

Naproxen:
  • < 1 month: 28.0% - (7 of 25 people)
  • 1 - 6 months: 26.0% - (6 of 23 people)
  • 6 - 12 months: 21.0% - (3 of 14 people)
  • 1 - 2 years: 26.0% - (6 of 23 people)
  • 2 - 5 years: 33.0% - (7 of 21 people)
  • 5 - 10 years: 22.0% - (2 of 9 people)
  • 10+ years: 60.0% - (9 of 15 people)
  • not specified: 0.0% - (0 of 2 people)
Omeprazole:
  • < 1 month: 40.0% - (4 of 10 people)
  • 1 - 6 months: 39.0% - (9 of 23 people)
  • 6 - 12 months: 42.0% - (6 of 14 people)
  • 1 - 2 years: 41.0% - (10 of 24 people)
  • 2 - 5 years: 84.0% - (27 of 32 people)
  • 5 - 10 years: 61.0% - (8 of 13 people)
  • 10+ years: 60.0% - (9 of 15 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Naproxen:
  • female: 30.0% - (27 of 90 people)
  • male: 30.0% - (13 of 42 people)
Omeprazole:
  • female: 51.0% - (47 of 91 people)
  • male: 63.0% - (26 of 41 people)

Drug effectiveness by age:

Naproxen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 36.0% - (4 of 11 people)
  • 30-39: 15.0% - (3 of 19 people)
  • 40-49: 34.0% - (10 of 29 people)
  • 50-59: 22.0% - (7 of 31 people)
  • 60+: 36.0% - (15 of 41 people)
Omeprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 36.0% - (4 of 11 people)
  • 30-39: 50.0% - (9 of 18 people)
  • 40-49: 56.0% - (17 of 30 people)
  • 50-59: 59.0% - (19 of 32 people)
  • 60+: 60.0% - (24 of 40 people)

Most common drug interactions over time *:

< 1 month:
  • sepsis
  • dyspnoea
  • pneumonia
  • vomiting
  • abdominal pain
  • stevens-johnson syndrome
  • diarrhoea
  • extrapyramidal disorder
  • rhabdomyolysis
  • insomnia
1 - 6 months:
  • nausea
  • abdominal pain upper
  • anxiety
  • dry mouth
  • depression
  • headache
  • insomnia
  • gait disturbance
  • abdominal pain
  • amnesia
6 - 12 months:
  • pain
  • hip fracture
  • osteopenia
  • rib fracture
  • stress fracture
  • bone density decreased
  • diarrhoea
  • death
  • depression
  • drug ineffective
1 - 2 years:
  • back pain
  • ibs
  • neck pain
  • dizziness
  • abdominal pain
  • fatigue - chronic
  • muscle spasms
  • bone disorder
  • paraesthesia
  • abdominal bloating
2 - 5 years:
  • anxiety
  • depression
  • headache
  • arthritis
  • pain
  • chest pain
  • anxiety disorder
  • bone disorder
  • fatigue
  • inflammatory pain
5 - 10 years:
  • anxiety
  • depression
  • myopathy
  • blood creatine phosphokinase increased
  • muscular weakness
  • pain in extremity
  • burning feet syndrome
  • dry mouth
  • lightheadedness
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
10+ years:
  • depression
  • osteoporosis
  • anxiety
  • fatigue
  • irritability
  • arthritis
  • fall
  • multiple fractures
  • carpal tunnel syndrome
  • intervertebral disc protrusion
not specified:
  • pain
  • nausea
  • arthralgia
  • anxiety
  • fatigue
  • dyspnoea
  • fall
  • depression
  • anaemia
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • arthralgia
  • fatigue
  • anxiety
  • dyspnoea
  • fall
  • pain in extremity
  • back pain
  • headache
male:
  • pain
  • anxiety
  • dyspnoea
  • depression
  • nausea
  • arthralgia
  • fatigue
  • injury
  • anaemia
  • drug ineffective

Most common drug interactions by age *:

0-1:
  • arthritis
  • osteoporosis
  • blood cholesterol increased
  • cerebrovascular accident
  • convulsion
  • diabetic neuropathy
  • dyspnoea
  • haematochezia
  • hypercalcaemia
  • hyperlipidaemia
2-9:
  • cough
  • blood immunoglobulin a decreased
  • blood immunoglobulin g decreased
  • feeling abnormal
  • headache
  • infection
  • lower respiratory tract infection
  • nausea
  • procedural headache
  • respiratory distress
10-19:
  • arthralgia
  • pyrexia
  • abdominal pain upper
  • tremor
  • agitation
  • hallucination
  • mydriasis
  • myoclonus
  • rhabdomyolysis
  • nausea
20-29:
  • pain
  • cholecystitis chronic
  • gallbladder disorder
  • injury
  • abdominal pain
  • anxiety
  • cholelithiasis
  • fatigue
  • deep vein thrombosis
  • pulmonary embolism
30-39:
  • pain
  • cholecystitis chronic
  • nausea
  • abdominal pain upper
  • cholelithiasis
  • pulmonary embolism
  • injury
  • chest pain
  • deep vein thrombosis
  • vomiting
40-49:
  • pain
  • headache
  • nausea
  • arthralgia
  • depression
  • anxiety
  • diabetes mellitus
  • dizziness
  • chest pain
  • drug ineffective
50-59:
  • pain
  • arthralgia
  • fatigue
  • anxiety
  • nausea
  • osteoarthritis
  • depression
  • back pain
  • osteonecrosis of jaw
  • anaemia
60+:
  • pain
  • dyspnoea
  • nausea
  • anxiety
  • fatigue
  • anaemia
  • fall
  • asthenia
  • diarrhoea
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Naproxen (naproxen) is often used to treat pain. Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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