Review: taking Naproxen and Omeprazole together


Summary

Drug interactions are reported among people who take Naproxen and Omeprazole together. This review analyzes the effectiveness and drug interactions between Naproxen and Omeprazole. It is created by eHealthMe based on reports of 3,715 people who take the same drugs from FDA and social media, and is updated regularly.

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Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 27,302 users)

Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Omeprazole 94,637 users)

On Jul, 26, 2016

3,715 people who take Naproxen, Omeprazole are studied.


Number of reports submitted per year:

Naproxen and Omeprazole drug interactions.

Drug effectiveness over time:

Naproxen:
  • < 1 month: 28.0% - (8 of 28 people)
  • 1 - 6 months: 24.0% - (9 of 37 people)
  • 6 - 12 months: 20.0% - (3 of 15 people)
  • 1 - 2 years: 21.0% - (7 of 33 people)
  • 2 - 5 years: 28.0% - (8 of 28 people)
  • 5 - 10 years: 26.0% - (4 of 15 people)
  • 10+ years: 56.0% - (13 of 23 people)
  • not specified: 0.0% - (0 of 2 people)
Omeprazole:
  • < 1 month: 40.0% - (4 of 10 people)
  • 1 - 6 months: 38.0% - (10 of 26 people)
  • 6 - 12 months: 41.0% - (7 of 17 people)
  • 1 - 2 years: 31.0% - (14 of 45 people)
  • 2 - 5 years: 76.0% - (36 of 47 people)
  • 5 - 10 years: 70.0% - (12 of 17 people)
  • 10+ years: 57.0% - (11 of 19 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Naproxen:
  • female: 30.0% - (39 of 129 people)
  • male: 25.0% - (13 of 52 people)
Omeprazole:
  • female: 46.0% - (61 of 130 people)
  • male: 63.0% - (33 of 52 people)

Drug effectiveness by age:

Naproxen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 50.0% - (8 of 16 people)
  • 30-39: 11.0% - (4 of 35 people)
  • 40-49: 30.0% - (12 of 39 people)
  • 50-59: 24.0% - (8 of 33 people)
  • 60+: 33.0% - (19 of 57 people)
Omeprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 31.0% - (5 of 16 people)
  • 30-39: 29.0% - (10 of 34 people)
  • 40-49: 56.0% - (23 of 41 people)
  • 50-59: 61.0% - (21 of 34 people)
  • 60+: 62.0% - (35 of 56 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • stevens-johnson syndrome
  • vomiting
  • diarrhoea
  • confusional state
  • purpura
  • lip swelling
  • sepsis
  • rash erythematous
  • conjunctivitis
1 - 6 months:
  • depression suicidal
  • self-injurious ideation
  • abdominal pain
  • nausea
  • abdominal pain diagnosis
  • burning feet syndrome
  • diarrhoea
  • ibs
  • joint instability
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
6 - 12 months:
  • pain
  • bone density decreased
  • hip fracture
  • osteopenia
  • rib fracture
  • stress fracture
  • diarrhoea
  • fall
  • nausea
  • vomiting
1 - 2 years:
  • ibs
  • fatigue - chronic
  • back pain
  • abdominal bloating
  • abdominal pain
  • back stiffness
  • breathlessness
  • farsightedness
  • finger swelling
  • loose stools
2 - 5 years:
  • anxiety
  • depression
  • headache
  • anxiety disorder
  • inflammatory pain
  • arthritis
  • chest pain
  • depression suicidal
  • facial nerve disorder
  • herniated intervertebral disk
5 - 10 years:
  • anxiety
  • depression
  • burning feet syndrome
  • dry mouth
  • lightheadedness
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • angular cheilitis
  • gum pain
  • hair loss
  • headache - migraine without aura
10+ years:
  • depression
  • fatigue
  • irritability
  • anxiety
  • adrenal neoplasm
  • blood glucose
  • carbohydrate craving
  • cataract cortical
  • dehydration
  • depressed mood
not specified:
  • pain
  • anxiety
  • arthralgia
  • nausea
  • dyspnoea
  • fatigue
  • anaemia
  • fall
  • back pain
  • injury

Most common drug interactions by gender *:

female:
  • pain
  • arthralgia
  • nausea
  • anxiety
  • fall
  • fatigue
  • dyspnoea
  • back pain
  • anaemia
  • vomiting
male:
  • pain
  • anxiety
  • dyspnoea
  • nausea
  • arthralgia
  • depression
  • injury
  • anaemia
  • fatigue
  • osteonecrosis of jaw

Most common drug interactions by age *:

0-1:
  • arthritis
  • blood cholesterol increased
  • cerebrovascular accident
  • convulsion
  • diabetic neuropathy
  • dyspnoea
  • haematochezia
  • hypercalcaemia
  • hyperlipidaemia
  • hypertension
2-9:
  • abdominal pain
  • arthralgia
  • aspartate aminotransferase increased
  • bacteriuria
  • blood pressure decreased
  • bone pain
  • cardiac arrest
  • chills
  • constipation
  • electrocardiogram st segment depression
10-19:
  • arthralgia
  • abdominal pain upper
  • pyrexia
  • cholecystitis chronic
  • pain
  • balance disorder
  • brain oedema
  • disseminated intravascular coagulation
  • drug rash with eosinophilia and systemic symptoms
  • multi-organ failure
20-29:
  • gallbladder disorder
  • cholecystitis chronic
  • pain
  • abdominal pain
  • cholelithiasis
  • fatigue
  • vomiting
  • anxiety
  • injury
  • cough
30-39:
  • cholecystitis chronic
  • cholelithiasis
  • pain
  • abdominal pain upper
  • nausea
  • chest pain
  • anxiety
  • deep vein thrombosis
  • pulmonary embolism
  • depression
40-49:
  • pain
  • depression
  • diabetes mellitus
  • nausea
  • anxiety
  • chest pain
  • weight increased
  • dizziness
  • headache
  • arthralgia
50-59:
  • pain
  • arthralgia
  • anxiety
  • fatigue
  • osteonecrosis of jaw
  • nausea
  • osteoarthritis
  • back pain
  • anaemia
  • depression
60+:
  • pain
  • dyspnoea
  • anxiety
  • nausea
  • fall
  • anaemia
  • asthenia
  • fatigue
  • arthralgia
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Naproxen (naproxen) is often used to treat pain. Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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