Review: taking Naproxen and Tylenol together


Summary

Drug interactions are reported among people who take Naproxen and Tylenol together. This review analyzes the effectiveness and drug interactions between Naproxen and Tylenol. It is created by eHealthMe based on reports of 4,217 people who take the same drugs from FDA and social media, and is updated regularly.

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Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 27,302 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 63,439 users)

On Jul, 22, 2016

4,217 people who take Naproxen, Tylenol are studied.


Number of reports submitted per year:

Naproxen and Tylenol drug interactions.

Drug effectiveness over time:

Naproxen:
  • < 1 month: 20.0% - (8 of 39 people)
  • 1 - 6 months: 25.0% - (5 of 20 people)
  • 6 - 12 months: 22.0% - (4 of 18 people)
  • 1 - 2 years: 11.0% - (1 of 9 people)
  • 2 - 5 years: 45.0% - (5 of 11 people)
  • 5 - 10 years: 27.0% - (3 of 11 people)
  • 10+ years: 36.0% - (4 of 11 people)
  • not specified: 0.0% - (0 of 2 people)
Tylenol:
  • < 1 month: 20.0% - (6 of 29 people)
  • 1 - 6 months: 7.0% - (1 of 14 people)
  • 6 - 12 months: 0.0% - (0 of 13 people)
  • 1 - 2 years: 11.0% - (1 of 9 people)
  • 2 - 5 years: 25.0% - (4 of 16 people)
  • 5 - 10 years: 40.0% - (6 of 15 people)
  • 10+ years: 15.0% - (3 of 20 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Naproxen:
  • female: 30.0% - (25 of 83 people)
  • male: 13.0% - (5 of 38 people)
Tylenol:
  • female: 20.0% - (17 of 82 people)
  • male: 13.0% - (5 of 38 people)

Drug effectiveness by age:

Naproxen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 50.0% - (1 of 2 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 10.0% - (2 of 20 people)
  • 30-39: 10.0% - (2 of 20 people)
  • 40-49: 28.0% - (8 of 28 people)
  • 50-59: 46.0% - (12 of 26 people)
  • 60+: 18.0% - (4 of 22 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 50.0% - (1 of 2 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 15.0% - (3 of 19 people)
  • 30-39: 23.0% - (5 of 21 people)
  • 40-49: 14.0% - (4 of 27 people)
  • 50-59: 20.0% - (5 of 25 people)
  • 60+: 17.0% - (4 of 23 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure acute
  • pneumonia
  • dyspnoea
  • gastrointestinal haemorrhage
  • diarrhoea
  • haemoglobin decreased
  • anaemia
  • dizziness
  • syncope
  • abdominal pain upper
1 - 6 months:
  • nausea
  • anxiety
  • suicide attempt
  • abdominal pain
  • dizziness
  • constipation
  • diarrhoea
  • pain
  • pyrexia
  • acute coronary syndrome
6 - 12 months:
  • renal failure acute
  • atrial fibrillation
  • diabetes mellitus
  • vasculitis
  • nausea
  • renal impairment
  • dizziness
  • insomnia
  • itching
  • muscle spasms
1 - 2 years:
  • dyspnoea
  • cerebral infarction
  • hypercholesterolaemia
  • cardiac failure congestive
  • gastrooesophageal reflux disease
  • temporomandibular joint syndrome
  • muscle spasms
  • respiratory distress
  • anaemia
  • blood bicarbonate increased
2 - 5 years:
  • back pain
  • arthralgia
  • drug ineffective
  • nausea
  • myocardial infarction
  • dizziness
  • hypertension
  • chronic obstructive pulmonary disease
  • depression
  • fatigue
5 - 10 years:
  • cerebrovascular accident
  • acute myocardial infarction
  • emotional distress
  • injury
  • renal disorder
  • aortic valve incompetence
  • cellulitis
  • hypertension
  • hypoaesthesia
  • hypokalaemia
10+ years:
  • depression
  • aphasia
  • chronic fatigue syndrome
  • cognitive disorder
  • confusion
  • fall
  • fatigue
  • irritability
  • sleep apnea
  • suicidal ideation
not specified:
  • pain
  • nausea
  • anxiety
  • fatigue
  • back pain
  • dyspnoea
  • arthralgia
  • dizziness
  • headache
  • chest pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • back pain
  • anxiety
  • fatigue
  • headache
  • dyspnoea
  • arthralgia
  • depression
  • dizziness
male:
  • pain
  • anxiety
  • dizziness
  • nausea
  • injury
  • dyspnoea
  • pyrexia
  • chest pain
  • fatigue
  • anaemia

Most common drug interactions by age *:

0-1:
  • arthralgia
  • breech presentation
  • cleft lip and palate
  • complex regional pain syndrome
  • congenital anomaly
  • drug exposure during pregnancy
  • drug ineffective
  • eosinophil count increased
  • eyelid oedema
  • facial dysmorphism
2-9:
  • gastroenteritis
  • impetigo
  • sinusitis
  • aspartate aminotransferase increased
  • neurofibromatosis
  • accidental overdose (therapeutic agent)
  • attention deficit/hyperactivity disorder
  • drug exposure during pregnancy
  • drug ineffective
  • international normalised ratio increased
10-19:
  • arthralgia
  • nausea
  • pain
  • vomiting
  • suicide attempt
  • weight decreased
  • pyrexia
  • cholecystitis chronic
  • pulmonary embolism
  • drug ineffective
20-29:
  • nausea
  • pain
  • vomiting
  • anxiety
  • insomnia
  • dyspnoea
  • cholecystitis chronic
  • cholelithiasis
  • urinary tract infection
  • headache
30-39:
  • pain
  • nausea
  • completed suicide
  • headache
  • chest pain
  • pulmonary embolism
  • fatigue
  • deep vein thrombosis
  • injury
  • migraine
40-49:
  • pain
  • chest pain
  • dizziness
  • arthralgia
  • dyspnoea
  • nausea
  • headache
  • fatigue
  • depression
  • diabetes mellitus
50-59:
  • anxiety
  • back pain
  • pain
  • depression
  • decreased appetite
  • nausea
  • osteonecrosis of jaw
  • fatigue
  • weight decreased
  • headache
60+:
  • pain
  • nausea
  • fatigue
  • dizziness
  • anxiety
  • asthenia
  • osteoarthritis
  • anaemia
  • weight decreased
  • back pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Naproxen (naproxen) is often used to treat pain. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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