Review: taking Neurontin and Methadone hydrochloride together


Summary

Drug interactions are reported among people who take Neurontin and Methadone hydrochloride together. This review analyzes the effectiveness and drug interactions between Neurontin and Methadone hydrochloride. It is created by eHealthMe based on reports of 3,043 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Neurontin

Neurontin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Neurontin 76,477 users)

Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 3,248 users)

On Sep, 20, 2016

3,043 people who take Neurontin, Methadone Hydrochloride are studied.


Number of reports submitted per year:

Neurontin and Methadone hydrochloride drug interactions.

Drug effectiveness over time:

Neurontin:
  • < 1 month: 22.0% - (2 of 9 people)
  • 1 - 6 months: 0.0% - (0 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 33.0% - (5 of 15 people)
  • 2 - 5 years: 23.0% - (4 of 17 people)
  • 5 - 10 years: 46.0% - (7 of 15 people)
  • 10+ years: 75.0% - (3 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • < 1 month: 30.0% - (3 of 10 people)
  • 1 - 6 months: 64.0% - (9 of 14 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 71.0% - (5 of 7 people)
  • 2 - 5 years: 50.0% - (7 of 14 people)
  • 5 - 10 years: 58.0% - (7 of 12 people)
  • 10+ years: 57.0% - (4 of 7 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Neurontin:
  • female: 27.0% - (11 of 40 people)
  • male: 33.0% - (10 of 30 people)
Methadone Hydrochloride:
  • female: 54.0% - (23 of 42 people)
  • male: 46.0% - (12 of 26 people)

Drug effectiveness by age:

Neurontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 38.0% - (7 of 18 people)
  • 40-49: 28.0% - (7 of 25 people)
  • 50-59: 8.0% - (1 of 12 people)
  • 60+: 44.0% - (4 of 9 people)
Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (4 of 6 people)
  • 30-39: 61.0% - (11 of 18 people)
  • 40-49: 50.0% - (12 of 24 people)
  • 50-59: 46.0% - (6 of 13 people)
  • 60+: 28.0% - (2 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • pneumonia
  • drug withdrawal syndrome
  • overdose
  • vomiting
  • dehydration
  • nausea
  • blood creatinine increased
  • electrocardiogram qt prolonged
  • general physical health deterioration
  • renal impairment
1 - 6 months:
  • vomiting
  • renal impairment
  • blood creatinine increased
  • glomerular filtration rate decreased
  • constipation
  • loss of consciousness
  • depressed level of consciousness
  • hepatic encephalopathy
  • oedema peripheral
  • abdominal pain upper
6 - 12 months:
  • drug ineffective
  • tooth disorder
  • disturbance in attention
  • erectile dysfunction
  • fine motor delay
  • vomiting
  • deep vein thrombosis
  • depression
  • drug dependence
  • fall
1 - 2 years:
  • depression
  • abnormal behaviour
  • dental caries
  • drug dependence
  • dysarthria
  • tooth abscess
  • drug abuse
  • drug ineffective
  • overdose
  • partner stress
2 - 5 years:
  • drug ineffective
  • diarrhoea
  • hallucination
  • oedema peripheral
  • osteomyelitis
  • angiopathy
  • cerebrovascular accident
  • chest pain
  • constipation
  • coordination abnormal
5 - 10 years:
  • chronic pain
  • diarrhoea
  • dehydration
  • hypotension
  • neutropenia
  • arthritis
  • haematocrit decreased
  • haemoglobin decreased
  • pain in extremity
10+ years:
  • renal failure
  • anxiety disorder
  • back pain
  • bone pain
  • sleepiness - during the day
  • cardiac arrest
  • edema
  • insomnia
  • respiratory depression
  • weight gain
not specified:
  • pain
  • anxiety
  • dyspnoea
  • back pain
  • nausea
  • osteonecrosis of jaw
  • fatigue
  • arthralgia
  • oedema peripheral
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • back pain
  • osteonecrosis of jaw
  • fatigue
  • fall
  • hypoaesthesia
  • oedema peripheral
male:
  • pain
  • anxiety
  • back pain
  • asthenia
  • dyspnoea
  • arthralgia
  • vomiting
  • fatigue
  • diarrhoea
  • pain in extremity

Most common drug interactions by age *:

0-1:
  • drug withdrawal syndrome neonatal
  • foetal exposure during pregnancy
  • trismus
  • alopecia
  • respiratory failure
  • back pain
  • cellulitis
  • contusion
  • fall
  • fatigue
2-9:
  • respiratory distress
  • bone pain
  • convulsion
  • disease progression
  • febrile neutropenia
  • hepatomegaly
  • jaundice
  • metastases to kidney
  • metastases to liver
  • neoplasm progression
10-19:
  • hypotension
  • haematocrit decreased
  • vomiting
  • pyrexia
  • nausea
  • cardiac arrest
  • completed suicide
  • caecitis
  • haemoglobin decreased
  • headache
20-29:
  • pain
  • drug abuse
  • pain in extremity
  • pneumonia
  • anxiety
  • cellulitis
  • headache
  • vomiting
  • bone disorder
  • depression
30-39:
  • back pain
  • osteonecrosis of jaw
  • anxiety
  • pain
  • pain in extremity
  • nausea
  • bone disorder
  • deep vein thrombosis
  • oedema peripheral
  • dyspnoea
40-49:
  • pain
  • dyspnoea
  • fatigue
  • anxiety
  • nausea
  • vomiting
  • oedema peripheral
  • depression
  • insomnia
  • back pain
50-59:
  • pain
  • anxiety
  • arthralgia
  • emotional distress
  • diarrhoea
  • osteonecrosis of jaw
  • fall
  • dyspnoea
  • pyrexia
  • back pain
60+:
  • pain
  • dyspnoea
  • pneumonia
  • weight decreased
  • back pain
  • anxiety
  • osteonecrosis of jaw
  • asthenia
  • osteoarthritis
  • osteomyelitis

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Neurontin and Methadone hydrochloride?

Can you answer these questions?

More questions for: Neurontin, Methadone hydrochloride

You may be interested in these reviews

More reviews for: Neurontin, Methadone hydrochloride

On eHealthMe, Neurontin (gabapentin) is often used to treat pain. Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.