Review: taking Neurontin and Primidone together


Summary

Drug interactions are reported among people who take Neurontin and Primidone together. This review analyzes the effectiveness and drug interactions between Neurontin and Primidone. It is created by eHealthMe based on reports of 388 people who take the same drugs from FDA and social media, and is updated regularly.

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Neurontin

Neurontin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Neurontin 56,860 users)

Primidone

Primidone has active ingredients of primidone. It is often used in tremor. (latest outcomes from Primidone 2,735 users)

On Jul, 28, 2016

388 people who take Neurontin, Primidone are studied.


Number of reports submitted per year:

Neurontin and Primidone drug interactions.

Drug effectiveness over time:

Neurontin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Primidone:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Neurontin:
  • female: 0.0% - (0 of 5 people)
  • male: 20.0% - (1 of 5 people)
Primidone:
  • female: 20.0% - (1 of 5 people)
  • male: 28.0% - (2 of 7 people)

Drug effectiveness by age:

Neurontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 14.0% - (1 of 7 people)
Primidone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 22.0% - (2 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • neuroleptic malignant syndrome
  • agitation
  • alanine aminotransferase increased
  • amnesia
  • aspartate aminotransferase increased
  • chills
  • cholestasis
  • clumsiness
  • convulsion
  • coordination abnormal
1 - 6 months:
  • aggression
  • bradycardia
  • disturbance in attention
  • drug ineffective
  • feeling abnormal
  • somnolence
  • tremor
  • vertigo
6 - 12 months:
  • coma
  • dehydration
  • drug effect decreased
  • loss of consciousness
  • mental status changes
  • nephropathy toxic
  • respiratory failure
  • somnolence
  • uraemic encephalopathy
1 - 2 years:
  • confusion
  • convulsion
  • coordination abnormal
  • depression
  • diabetic nephropathy
  • diplopia
  • drowsiness
  • insomnia
  • neuropathy peripheral
  • tremor
2 - 5 years:
  • liver fatty
  • malaise
  • overdose
  • pyrexia
  • completed suicide
  • enterococcal infection
  • hyperhidrosis
5 - 10 years:
  • loss of smell
  • loss of taste
  • short-term memory loss
10+ years:
  • high blood pressure
  • raynaud's phenomenon
  • seizure - grand mal
  • simvastatin
not specified:
  • fall
  • asthenia
  • convulsion
  • fatigue
  • depression
  • tremor
  • pain
  • pneumonia
  • muscle spasms
  • urinary tract infection

Most common drug interactions by gender *:

female:
  • fall
  • convulsion
  • asthenia
  • depression
  • fatigue
  • pain
  • urinary tract infection
  • dysphagia
  • osteonecrosis of jaw
  • gait disturbance
male:
  • somnolence
  • tremor
  • back pain
  • hypertension
  • fall
  • myalgia
  • palpitations
  • dyspnoea
  • fatigue
  • muscle spasms

Most common drug interactions by age *:

10-19:
  • aggression
  • coma
  • dehydration
  • disturbance in attention
  • loss of consciousness
  • mental status changes
  • myoclonic jerks
  • nephropathy toxic
  • respiratory failure
  • somnolence
20-29:
  • dysmenorrhoea
  • fibrocystic breast disease
  • menorrhagia
  • non-accidental overdose
  • breast pain
  • fibroadenoma of breast
  • hormone level nos abnormal
  • suicide attempt
  • cardio-respiratory arrest
  • face oedema
30-39:
  • convulsion
  • injury
  • myalgia
  • alanine aminotransferase increased
  • anhedonia
  • anxiety
  • aspartate aminotransferase increased
  • asthenia
  • blood glucose decreased
  • bone callus excessive
40-49:
  • convulsion
  • weight increased
  • back pain
  • ecchymosis
  • muscle spasms
  • arthralgia
  • neck pain
  • palpitations
  • fatigue
  • anorexia
50-59:
  • diabetes mellitus
  • fall
  • nausea
  • fatigue
  • asthenia
  • insomnia
  • cerebrovascular accident
  • dizziness
  • neuropathy peripheral
  • somnolence
60+:
  • fall
  • dyspnoea
  • pneumonia
  • atrial fibrillation
  • tremor
  • essential tremor
  • constipation
  • rib fracture
  • asthenia
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Neurontin (gabapentin) is often used to treat pain. Primidone (primidone) is often used to treat tremor. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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