Review: taking Neurontin and Subutex together


Summary

Drug interactions are reported among people who take Neurontin and Subutex together. This review analyzes the effectiveness and drug interactions between Neurontin and Subutex. It is created by eHealthMe based on reports of 576 people who take the same drugs from FDA and social media, and is updated regularly.

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Neurontin

Neurontin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Neurontin 76,477 users)

Subutex

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in drug dependence. (latest outcomes from Subutex 5,007 users)

On Sep, 10, 2016

576 people who take Neurontin, Subutex are studied.


Number of reports submitted per year:

Neurontin and Subutex drug interactions.

Drug effectiveness over time:

Neurontin:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Subutex:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 57.0% - (4 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 80.0% - (4 of 5 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Neurontin:
  • female: 20.0% - (2 of 10 people)
  • male: 10.0% - (1 of 10 people)
Subutex:
  • female: 54.0% - (6 of 11 people)
  • male: 60.0% - (6 of 10 people)

Drug effectiveness by age:

Neurontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 14.0% - (1 of 7 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 33.0% - (1 of 3 people)
Subutex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 50.0% - (3 of 6 people)
  • 50-59: 60.0% - (3 of 5 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • rash
  • vomiting
  • pain
  • diarrhoea
  • dizziness
  • drug ineffective
  • tinnitus
  • migraine
  • nightmare
1 - 6 months:
  • premature delivery
  • pain
  • premature labour
  • paraesthesia
  • application site erythema
  • application site pruritus
  • drug ineffective
  • erythema
  • hypoaesthesia
  • sleep walking
6 - 12 months:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • anxiety
  • application site pruritus
  • chills
  • drug withdrawal syndrome
  • feeding disorder neonatal
  • jaundice neonatal
  • low birth weight baby
  • lung infection
1 - 2 years:
  • congenital diaphragmatic hernia
  • depression
  • fatigue
  • foetal exposure during pregnancy
  • hypertension
  • insomnia
  • premature baby
  • affect lability
  • anger
  • anhedonia
2 - 5 years:
  • pyrexia
  • confusional state
  • headache
  • sweating - excessive
  • alopecia
  • anxiety
  • hepatic encephalopathy
  • hepatic failure
  • chills
  • oedema
5 - 10 years:
  • fatigue
10+ years:
  • myocardial infarction
  • back pain - low
  • cognitive disorder
  • deep vein thrombosis
  • ischaemic stroke
not specified:
  • nausea
  • dizziness
  • vomiting
  • pain
  • fall
  • diarrhoea
  • anxiety
  • insomnia
  • pyrexia
  • dry mouth

Most common drug interactions by gender *:

female:
  • dizziness
  • pain
  • nausea
  • vomiting
  • diarrhoea
  • fall
  • insomnia
  • anxiety
  • dry mouth
  • pain in extremity
male:
  • nausea
  • drug withdrawal syndrome
  • vomiting
  • headache
  • depression
  • paraesthesia
  • dehydration
  • pain
  • corneal ulcer
  • hyperbilirubinaemia

Most common drug interactions by age *:

0-1:
  • atrial septal defect
  • small for dates baby
  • ventricular septal defect
10-19:
  • cardiac arrest
  • cardio-respiratory arrest
  • respiratory arrest
  • death
  • poisoning
  • cardiac failure
  • pleural effusion
20-29:
  • dizziness
  • nausea
  • pain
  • feeling abnormal
  • hypoaesthesia
  • loss of consciousness
  • fall
  • somnolence
  • vomiting
  • application site rash
30-39:
  • headache
  • depression
  • oral candidiasis
  • paraesthesia
  • corneal ulcer
  • hyperbilirubinaemia
  • keratitis
  • bronchitis
  • eyelid ptosis
  • scab
40-49:
  • depression
  • dizziness
  • drug withdrawal syndrome
  • fall
  • fatigue
  • vomiting
  • anger
  • anxiety
  • asthenia
  • cardiac arrest
50-59:
  • dizziness
  • insomnia
  • pain
  • pyrexia
  • vomiting
  • anxiety
  • fall
  • diarrhoea
  • hypoaesthesia
  • arthralgia
60+:
  • nausea
  • somnolence
  • vomiting
  • pain
  • dehydration
  • depression
  • confusional state
  • pneumonia aspiration
  • dizziness
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Neurontin (gabapentin) is often used to treat pain. Subutex (buprenorphine hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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