Review: taking Nexium and Aspirin together


Summary

Drug interactions are reported among people who take Nexium and Aspirin together. This review analyzes the effectiveness and drug interactions between Nexium and Aspirin. It is created by eHealthMe based on reports of 8,461 people who take the same drugs from FDA and social media, and is updated regularly.

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Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 73,364 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 160,694 users)

On Jul, 20, 2016

8,461 people who take Nexium, Aspirin are studied.


Number of reports submitted per year:

Nexium and Aspirin drug interactions.

Drug effectiveness over time:

Nexium:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 54.0% - (13 of 24 people)
  • 6 - 12 months: 57.0% - (8 of 14 people)
  • 1 - 2 years: 62.0% - (17 of 27 people)
  • 2 - 5 years: 65.0% - (49 of 75 people)
  • 5 - 10 years: 83.0% - (46 of 55 people)
  • 10+ years: 45.0% - (17 of 37 people)
  • not specified: 100.0% - (1 of 1 people)
Aspirin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 16.0% - (1 of 6 people)
  • 6 - 12 months: 46.0% - (6 of 13 people)
  • 1 - 2 years: 35.0% - (5 of 14 people)
  • 2 - 5 years: 58.0% - (27 of 46 people)
  • 5 - 10 years: 48.0% - (19 of 39 people)
  • 10+ years: 51.0% - (24 of 47 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Nexium:
  • female: 63.0% - (75 of 118 people)
  • male: 63.0% - (77 of 121 people)
Aspirin:
  • female: 46.0% - (32 of 69 people)
  • male: 50.0% - (50 of 99 people)

Drug effectiveness by age:

Nexium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 70.0% - (7 of 10 people)
  • 40-49: 58.0% - (20 of 34 people)
  • 50-59: 75.0% - (60 of 79 people)
  • 60+: 56.0% - (65 of 116 people)
Aspirin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 55.0% - (5 of 9 people)
  • 40-49: 52.0% - (10 of 19 people)
  • 50-59: 46.0% - (27 of 58 people)
  • 60+: 48.0% - (40 of 82 people)

Most common drug interactions over time *:

< 1 month:
  • fall
  • drug rash with eosinophilia and systemic symptoms
  • liver injury
  • tracheobronchitis
  • disorientation
  • neutropenia
  • acute abdomen
  • rash
  • pyrexia
  • aspartate aminotransferase increased
1 - 6 months:
  • fatigue
  • thrombocytopenia
  • angioedema
  • drug ineffective
  • swollen tongue
  • anaemia
  • haemoglobin decreased
  • atrial fibrillation
  • chest pain
  • diarrhoea
6 - 12 months:
  • encephalopathy
  • hepatic failure
  • hepatitis cholestatic
  • duodenal ulcer
  • hepatic neoplasm malignant
  • portal vein thrombosis
  • jaundice cholestatic
  • streptococcal infection
  • alcoholism
  • cytolytic hepatitis
1 - 2 years:
  • dyspnoea
  • dizziness
  • fatigue
  • gastritis
  • back pain
  • cough
  • diarrhoea
  • haemorrhoids
  • headache
  • metrorrhagia
2 - 5 years:
  • sepsis
  • multi-organ failure
  • involuntary body movements
  • mouth dry aggravated
  • pneumonia
  • stuttering
  • tremor - drug-induced
  • vomiting
  • abdominal pain
  • angina pectoris
5 - 10 years:
  • gangrene - gas
  • lightheadedness
  • anger
  • diarrhoea
  • gastrooesophageal reflux disease
  • muscle spasms
  • respiratory disorder
  • tendonitis
  • alopecia
  • arthralgia
10+ years:
  • gangrene - gas
  • lightheadedness
  • renal failure acute
  • bone loss
  • heart attack
  • irregular heartbeat
  • multi-organ failure
  • pneumonia
  • prostate cancer metastatic
  • reflux laryngitis
not specified:
  • pain
  • nausea
  • dyspnoea
  • dizziness
  • anxiety
  • asthenia
  • diarrhoea
  • chest pain
  • fatigue
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • dyspnoea
  • diarrhoea
  • fall
  • asthenia
  • anxiety
  • dizziness
  • fatigue
  • pain in extremity
male:
  • dyspnoea
  • pain
  • nausea
  • anxiety
  • dizziness
  • pneumonia
  • chest pain
  • weight decreased
  • asthenia
  • myocardial infarction

Most common drug interactions by age *:

0-1:
  • anorexia
  • atrial fibrillation
  • confusional state
  • dyspnoea
  • hypotension
  • pneumonia
  • chronic obstructive pulmonary disease
  • death
  • ejection fraction decreased
  • alopecia
2-9:
  • acute respiratory distress syndrome
  • cardiac failure
  • hepatocellular injury
  • peritonitis
  • pneumothorax
  • respiratory failure
  • thrombocytopenia
  • abdominal pain
  • capillary leak syndrome
  • cardiovascular disorder
10-19:
  • drug ineffective
  • agitation postoperative
  • alpha 1 foetoprotein increased
  • confusion postoperative
  • hallucination, visual
  • hepatic fibrosis
  • hepatic neoplasm malignant
  • immunosuppressant drug level increased
  • liver disorder
  • liver transplant
20-29:
  • nausea
  • diarrhoea
  • dyspnoea
  • fatigue
  • pyrexia
  • hodgkin's disease
  • night sweats
  • anxiety
  • dizziness
  • insomnia
30-39:
  • dizziness
  • nausea
  • abdominal pain
  • arthralgia
  • dyspnoea
  • headache
  • neck pain
  • diarrhoea
  • drug ineffective
  • fatigue
40-49:
  • pain
  • nausea
  • headache
  • chest pain
  • pain in extremity
  • anxiety
  • fatigue
  • dizziness
  • myocardial infarction
  • oedema peripheral
50-59:
  • nausea
  • pain
  • dyspnoea
  • chest pain
  • anxiety
  • dizziness
  • diarrhoea
  • weight decreased
  • vomiting
  • pain in extremity
60+:
  • pain
  • dyspnoea
  • nausea
  • asthenia
  • fall
  • diarrhoea
  • anxiety
  • dizziness
  • anaemia
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Nexium (esomeprazole magnesium) is often used to treat gastrooesophageal reflux disease. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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