Review: taking Nexium and Imodium together


Summary

Drug interactions are reported among people who take Nexium and Imodium together. This review analyzes the effectiveness and drug interactions between Nexium and Imodium. It is created by eHealthMe based on reports of 1,572 people who take the same drugs from FDA and social media, and is updated regularly.

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Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 115,436 users)

Imodium

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. (latest outcomes from Imodium 16,915 users)

On Sep, 16, 2016

1,572 people who take Nexium, Imodium are studied.


Number of reports submitted per year:

Nexium and Imodium drug interactions.

Drug effectiveness over time:

Nexium:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Imodium:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Nexium:
  • female: 50.0% - (2 of 4 people)
  • male: 25.0% - (1 of 4 people)
Imodium:
  • female: 75.0% - (3 of 4 people)
  • male: 33.0% - (1 of 3 people)

Drug effectiveness by age:

Nexium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 0 people)
Imodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 75.0% - (3 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • vomiting
  • nausea
  • renal impairment
  • thrombocytopenia
  • anastomotic haemorrhage
  • complications of transplanted kidney
  • escherichia sepsis
  • anaemia
  • abdominal pain
1 - 6 months:
  • fungal oesophagitis
  • diarrhoea
  • death
  • hypertension
  • malignant neoplasm progression
  • myocardial infarction
  • abdominal pain
  • agranulocytosis
  • aspergillosis
  • clostridium difficile colitis
6 - 12 months:
  • death
  • gastrooesophageal reflux disease
  • generalised oedema
  • malaise
  • blindness
  • chest discomfort
  • decreased appetite
  • dyspnoea
  • hyperchlorhydria
  • hypertension
1 - 2 years:
  • hypercalcaemia
  • hypersensitivity
  • pain
  • peripheral swelling
  • psoriatic arthropathy
  • somnolence
2 - 5 years:
  • pain
  • chest pain
  • gastrooesophageal reflux disease
  • abdominal pain upper
  • biliary colic
  • blood calcium decreased
  • cholecystitis chronic
  • death
  • fall
  • fatigue
5 - 10 years:
  • diarrhoea
  • abdominal discomfort
  • facial bones fracture
  • insomnia
  • psychotic disorder
  • activities of daily living impaired
  • aphagia
  • colitis
  • convulsion
  • diabetes mellitus
10+ years:
  • ankle fracture
  • arthritis
  • bone disorder
  • cataract
  • chronic obstructive pulmonary disease
  • depression
  • fall
  • femur fracture
  • osteoporosis
  • rheumatoid arthritis
not specified:
  • diarrhoea
  • nausea
  • vomiting
  • fatigue
  • dyspnoea
  • dehydration
  • pyrexia
  • asthenia
  • anaemia
  • pneumonia

Most common drug interactions by gender *:

female:
  • diarrhoea
  • nausea
  • vomiting
  • dyspnoea
  • fatigue
  • dehydration
  • pyrexia
  • anxiety
  • anaemia
  • pain
male:
  • diarrhoea
  • nausea
  • vomiting
  • fatigue
  • dehydration
  • renal failure acute
  • asthenia
  • anaemia
  • pyrexia
  • pneumonia

Most common drug interactions by age *:

0-1:
  • hypomagnesaemia
2-9:
  • abdominal pain
  • accidental drug intake by child
  • agitation
  • ataxia
  • confusional state
  • convulsion
  • hallucination
  • hypertension
  • mydriasis
  • nausea
10-19:
  • dizziness
  • gallbladder disorder
  • small intestinal obstruction
  • cerebrovascular accident
  • colitis
  • nausea
  • vomiting
  • back disorder
  • bunion
  • cataract
20-29:
  • pyrexia
  • renal failure
  • abdominal compartment syndrome
  • atrial flutter
  • bacterial infection
  • clostridium difficile colitis
  • diarrhoea
  • gastric ulcer
  • haemodynamic instability
  • hepatic failure
30-39:
  • dyspnoea
  • pneumonia
  • pain
  • paraesthesia
  • hypoaesthesia
  • nausea
  • vomiting
  • wound secretion
  • blister
  • cellulitis
40-49:
  • diarrhoea
  • dehydration
  • nausea
  • vomiting
  • dyspnoea
  • priapism
  • fatigue
  • malaise
  • insomnia
  • abdominal pain
50-59:
  • diarrhoea
  • nausea
  • vomiting
  • pneumonia
  • dyspnoea
  • gastrointestinal haemorrhage
  • arrhythmia
  • pulmonary hypertension
  • renal failure acute
  • fatigue
60+:
  • diarrhoea
  • nausea
  • vomiting
  • asthenia
  • fatigue
  • dehydration
  • pyrexia
  • fall
  • anaemia
  • hypertension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Nexium (esomeprazole magnesium) is often used to treat gastrooesophageal reflux disease. Imodium (loperamide hydrochloride) is often used to treat diarrhea. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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