Review: taking Niacin and Methotrexate together


Summary

Drug interactions are reported among people who take Niacin and Methotrexate together. This review analyzes the effectiveness and drug interactions between Niacin and Methotrexate. It is created by eHealthMe based on reports of 322 people who take the same drugs from FDA and social media, and is updated regularly.

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Niacin

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. (latest outcomes from Niacin 6,361 users)

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,243 users)

On Jul, 27, 2016

322 people who take Niacin, Methotrexate are studied.


Number of reports submitted per year:

Niacin and Methotrexate drug interactions.

Drug effectiveness over time:

Niacin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methotrexate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Niacin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 4 people)
Methotrexate:
  • female: 66.0% - (2 of 3 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Niacin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 50.0% - (1 of 2 people)
Methotrexate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • abdominal pain
  • muscle spasms
  • retching
  • stomatitis
  • flushing
  • pruritus
  • burning sensation
  • drug ineffective
  • erythema
1 - 6 months:
  • burning sensation
  • flushing
  • pruritus
  • pain of skin
  • aggression
  • asthenia
  • diarrhoea
  • fatigue
  • fear
  • impatience
6 - 12 months:
  • headache
  • nasal congestion
  • nasopharyngitis
  • pyrexia
  • sinus congestion
  • sinusitis
1 - 2 years:
  • cellulitis
  • chronic obstructive pulmonary disease
  • flushing
  • oedema
  • pruritus
  • respiratory failure
  • breast cancer
  • erythema
  • rash
  • rheumatoid arthritis
2 - 5 years:
  • erectile dysfunction
  • headache
  • flushing
  • hepatitis
  • hot flush
  • osteolysis
  • pruritus generalised
  • rash
5 - 10 years:
  • atrial septal defect
  • cerebral artery embolism
  • retinal artery occlusion
  • anaemia
  • dizziness postural
  • duodenal ulcer
  • gastrointestinal ulcer haemorrhage
  • haemodynamic instability
  • intestinal ulcer
  • malaise
not specified:
  • flushing
  • fall
  • dizziness
  • diarrhoea
  • vomiting
  • headache
  • myalgia
  • pneumonia
  • arthralgia
  • dyspnoea

Most common drug interactions by gender *:

female:
  • fall
  • diarrhoea
  • dizziness
  • back pain
  • headache
  • road traffic accident
  • fatigue
  • pneumonia
  • vomiting
  • cough
male:
  • flushing
  • drug ineffective
  • pruritus
  • injection site haematoma
  • stomatitis
  • vomiting
  • feeling hot
  • pain in extremity
  • blood glucose increased
  • nausea

Most common drug interactions by age *:

30-39:
  • diarrhoea
  • dizziness
  • vomiting
  • abdominal pain lower
  • areflexia
  • arthropathy
  • breast cyst
  • breast pain
  • bursitis
  • cyst
40-49:
  • abdominal pain
  • muscle spasms
  • retching
  • stomatitis
  • vomiting
  • injection site pain
  • feeling hot
  • injection site haemorrhage
  • erythema
  • flushing
50-59:
  • flushing
  • pruritus
  • drug ineffective
  • chest pain
  • dizziness
  • dry skin
  • pain in extremity
  • pulmonary tuberculosis
  • fatigue
  • headache
60+:
  • flushing
  • pain
  • pruritus
  • drug ineffective
  • fall
  • tooth extraction
  • arthralgia
  • back pain
  • cellulitis
  • erythema

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Niacin (niacin) is often used to treat high blood cholesterol. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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