Review: taking Niacin and Methotrexate together


Summary

Drug interactions are reported among people who take Niacin and Methotrexate together. This review analyzes the effectiveness and drug interactions between Niacin and Methotrexate. It is created by eHealthMe based on reports of 545 people who take the same drugs from FDA and social media, and is updated regularly.

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Niacin

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. (latest outcomes from Niacin 7,412 users)

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,731 users)

On Sep, 20, 2016

545 people who take Niacin, Methotrexate are studied.


Number of reports submitted per year:

Niacin and Methotrexate drug interactions.

Drug effectiveness over time:

Niacin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methotrexate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Niacin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 4 people)
Methotrexate:
  • female: 66.0% - (2 of 3 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Niacin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 50.0% - (1 of 2 people)
Methotrexate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • abdominal pain
  • muscle spasms
  • retching
  • stomatitis
  • flushing
  • burning sensation
  • pruritus
  • drug ineffective
  • erythema
1 - 6 months:
  • pruritus
  • burning sensation
  • flushing
  • pain of skin
  • aggression
  • asthenia
  • clostridium difficile colitis
  • diarrhoea
  • erythema
  • fatigue
6 - 12 months:
  • intervertebral disc degeneration
  • overdose
  • diarrhoea
  • headache
  • nasal congestion
  • nasopharyngitis
  • pain in extremity
  • pyrexia
  • rash
  • rheumatoid arthritis
1 - 2 years:
  • cellulitis
  • chronic obstructive pulmonary disease
  • dyspnoea
  • flushing
  • oedema
  • pruritus
  • respiratory failure
  • breast cancer
  • erythema
  • joint swelling
2 - 5 years:
  • erectile dysfunction
  • headache
  • hodgkin's disease nodular sclerosis stage iv
  • acute sinusitis
  • aortic stenosis
  • atrophy
  • cerebrovascular accident
  • cerebrovascular disorder
  • dysarthria
  • flatulence
5 - 10 years:
  • anaemia
  • dizziness postural
  • duodenal ulcer
  • gastrointestinal ulcer haemorrhage
  • haemodynamic instability
  • intestinal ulcer
  • malaise
  • atrial septal defect
  • cerebral artery embolism
  • retinal artery occlusion
10+ years:
  • alopecia
  • hypersensitivity
  • pneumonia pneumococcal
  • rash
  • rash generalised
  • sepsis
  • skin exfoliation
not specified:
  • flushing
  • arthralgia
  • fall
  • headache
  • nausea
  • dizziness
  • fatigue
  • diarrhoea
  • pain in extremity
  • back pain

Most common drug interactions by gender *:

female:
  • arthralgia
  • fall
  • back pain
  • headache
  • diarrhoea
  • vomiting
  • fatigue
  • nausea
  • cough
  • dizziness
male:
  • flushing
  • drug ineffective
  • pain
  • nausea
  • pain in extremity
  • fall
  • arthralgia
  • dizziness
  • pruritus
  • feeling hot

Most common drug interactions by age *:

2-9:
  • arthralgia
  • diabetes mellitus
  • dry eye
  • erythema nodosum
  • eye infection
  • eye inflammation
  • eye irritation
  • eye pruritus
  • feeling abnormal
  • headache
30-39:
  • diarrhoea
  • dizziness
  • vomiting
  • abdominal pain lower
  • areflexia
  • arthropathy
  • breast cyst
  • breast pain
  • bursitis
  • cyst
40-49:
  • vomiting
  • abdominal pain
  • muscle spasms
  • retching
  • stomatitis
  • drug ineffective
  • injection site pain
  • rash
  • feeling hot
  • flushing
50-59:
  • drug ineffective
  • flushing
  • pruritus
  • pain
  • pain in extremity
  • injection site pain
  • nausea
  • stomatitis
  • headache
  • injection site swelling
60+:
  • flushing
  • pain
  • drug ineffective
  • arthralgia
  • fall
  • pruritus
  • back pain
  • injection site pain
  • rheumatoid arthritis
  • nausea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Niacin (niacin) is often used to treat high blood cholesterol. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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