Review: taking Norco and Coumadin together


Summary

Drug interactions are reported among people who take Norco and Coumadin together. This review analyzes the effectiveness and drug interactions between Norco and Coumadin. It is created by eHealthMe based on reports of 5,908 people who take the same drugs from FDA and social media, and is updated regularly.

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Norco

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Norco 8,641 users)

Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 80,735 users)

On Aug, 19, 2016

5,908 people who take Norco, Coumadin are studied.


Number of reports submitted per year:

Norco and Coumadin drug interactions.

Drug effectiveness over time:

Norco:
  • < 1 month: 22.0% - (2 of 9 people)
  • 1 - 6 months: 28.0% - (4 of 14 people)
  • 6 - 12 months: 20.0% - (3 of 15 people)
  • 1 - 2 years: 36.0% - (4 of 11 people)
  • 2 - 5 years: 38.0% - (7 of 18 people)
  • 5 - 10 years: 0.0% - (0 of 4 people)
  • 10+ years: 37.0% - (3 of 8 people)
  • not specified: 50.0% - (1 of 2 people)
Coumadin:
  • < 1 month: 57.0% - (4 of 7 people)
  • 1 - 6 months: 47.0% - (9 of 19 people)
  • 6 - 12 months: 42.0% - (3 of 7 people)
  • 1 - 2 years: 44.0% - (4 of 9 people)
  • 2 - 5 years: 54.0% - (6 of 11 people)
  • 5 - 10 years: 90.0% - (9 of 10 people)
  • 10+ years: 87.0% - (7 of 8 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Norco:
  • female: 34.0% - (16 of 46 people)
  • male: 22.0% - (8 of 35 people)
Coumadin:
  • female: 60.0% - (24 of 40 people)
  • male: 58.0% - (18 of 31 people)

Drug effectiveness by age:

Norco:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 33.0% - (4 of 12 people)
  • 50-59: 22.0% - (5 of 22 people)
  • 60+: 33.0% - (12 of 36 people)
Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (3 of 3 people)
  • 30-39: 33.0% - (2 of 6 people)
  • 40-49: 63.0% - (7 of 11 people)
  • 50-59: 52.0% - (10 of 19 people)
  • 60+: 62.0% - (20 of 32 people)

Most common drug interactions over time *:

< 1 month:
  • fall
  • international normalised ratio increased
  • coagulopathy
  • hypertension
  • malaise
  • deep vein thrombosis
  • haemorrhagic stroke
  • cold sweat
  • insomnia
  • dyspnoea
1 - 6 months:
  • dyspnoea
  • chest pain
  • pain
  • cardiac failure congestive
  • cellulitis
  • myocardial infarction
  • emotional distress
  • headache
  • pain in extremity
  • anaemia
6 - 12 months:
  • hyperthyroidism
  • hypothyroidism
  • pain
  • pulmonary embolism
  • deep vein thrombosis
  • dyspnoea
  • pain in extremity
  • oedema peripheral
  • thyroiditis subacute
  • emotional distress
1 - 2 years:
  • urinary tract infection
  • pulmonary embolism
  • bleeding from the nose
  • cerebral thrombosis
  • diverticulum intestinal haemorrhagic
  • eye disorder
  • headache
  • superior sagittal sinus thrombosis
  • vomiting
  • abdominal pain
2 - 5 years:
  • haemorrhagic stroke
  • fall
  • cold sweat
  • malaise
  • hypertension
  • feeling abnormal
  • aneurysm
  • insomnia
  • coagulopathy
  • apnoea
5 - 10 years:
  • headache
  • suicidal ideation
  • hysterectomy
  • gait disturbance
  • anhedonia
  • anxiety
  • emotional distress
  • joint range of motion decreased
  • nephrogenic systemic fibrosis
  • pain
10+ years:
  • breast cancer female
  • dementia
  • dyspnoea at rest
  • endometrial cancer
  • impaired memory
  • ischaemic stroke
  • lymphoma
  • constipation aggravated
  • fatigue - chronic
  • sleep disorder due to general medical condition, insomnia type
not specified:
  • pain
  • anxiety
  • dyspnoea
  • nausea
  • injury
  • anaemia
  • back pain
  • fatigue
  • asthenia
  • oedema peripheral

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • injury
  • back pain
  • asthenia
  • arthralgia
  • fall
  • anaemia
male:
  • pain
  • dyspnoea
  • anxiety
  • anaemia
  • injury
  • nausea
  • fatigue
  • oedema peripheral
  • asthenia
  • back pain

Most common drug interactions by age *:

0-1:
  • deep vein thrombosis
  • neuroleptic malignant syndrome
  • pulmonary embolism
  • suicide attempt
  • systemic lupus erythematosus
  • type 2 diabetes mellitus
  • therapeutic response decreased
2-9:
  • anaemia
  • fall
  • nausea
  • abdominal pain
  • actinic keratosis
  • appendicitis
  • bone disorder
  • cardiac failure congestive
  • cardiac murmur
  • cardiomyopathy
10-19:
  • arthralgia
  • pain
  • pulmonary embolism
  • anxiety
  • back pain
  • fatigue
  • dyspnoea
  • headache
  • injury
  • decreased appetite
20-29:
  • pain
  • headache
  • deep vein thrombosis
  • back pain
  • nausea
  • pulmonary embolism
  • insomnia
  • dyspnoea
  • pain in extremity
  • bronchitis
30-39:
  • anxiety
  • pulmonary embolism
  • pain
  • dyspnoea
  • back pain
  • deep vein thrombosis
  • chest pain
  • nausea
  • oedema peripheral
  • injury
40-49:
  • pain
  • anxiety
  • pain in extremity
  • dyspnoea
  • back pain
  • nausea
  • bone disorder
  • deep vein thrombosis
  • osteonecrosis of jaw
  • fatigue
50-59:
  • pain
  • anxiety
  • anaemia
  • oedema peripheral
  • injury
  • back pain
  • osteonecrosis of jaw
  • nausea
  • dyspnoea
  • arthralgia
60+:
  • pain
  • dyspnoea
  • anxiety
  • asthenia
  • fall
  • nausea
  • anaemia
  • injury
  • atrial fibrillation
  • cardiac failure congestive

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Norco (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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