Review: taking Nortriptyline hydrochloride and Pregabalin together


Summary

Drug interactions are reported among people who take Nortriptyline hydrochloride and Pregabalin together. This review analyzes the effectiveness and drug interactions between Nortriptyline hydrochloride and Pregabalin. It is created by eHealthMe based on reports of 1,009 people who take the same drugs from FDA and social media, and is updated regularly.

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Nortriptyline Hydrochloride

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in depression. (latest outcomes from Nortriptyline hydrochloride 1,707 users)

Pregabalin

Pregabalin has active ingredients of pregabalin. It is often used in pain. (latest outcomes from Pregabalin 10,039 users)

On Sep, 16, 2016

1,009 people who take Nortriptyline Hydrochloride, Pregabalin are studied.


Number of reports submitted per year:

Nortriptyline hydrochloride and Pregabalin drug interactions.

Drug effectiveness over time:

Nortriptyline Hydrochloride:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 16.0% - (1 of 6 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Pregabalin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 60.0% - (3 of 5 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 37.0% - (3 of 8 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Nortriptyline Hydrochloride:
  • female: 31.0% - (5 of 16 people)
  • male: 18.0% - (2 of 11 people)
Pregabalin:
  • female: 31.0% - (5 of 16 people)
  • male: 36.0% - (4 of 11 people)

Drug effectiveness by age:

Nortriptyline Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 14.0% - (1 of 7 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 28.0% - (2 of 7 people)
Pregabalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 0.0% - (0 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • weight increased
  • cardiac failure
  • oedema peripheral
  • rhabdomyolysis
  • feeling abnormal
  • pain
  • incontinence
  • abdominal pain upper
  • insomnia
1 - 6 months:
  • weight increased
  • pain
  • dizziness
  • depression
  • nausea
  • abdominal pain upper
  • balance disorder
  • decreased appetite
  • drug ineffective
  • anxiety
6 - 12 months:
  • weight increased
  • pain
  • cerebral infarction
  • dizziness
  • pain in extremity
  • intestinal obstruction
  • abdominal pain upper
  • anxiety
  • body height decreased
  • decreased appetite
1 - 2 years:
  • vision blurred
  • pain
  • weight increased
  • anxiety
  • balance disorder
  • drug ineffective
  • gait disturbance
  • amnesia
  • arthritis infective
  • burning sensation
2 - 5 years:
  • abortion spontaneous
  • pancreatitis
  • diabetes mellitus
  • chest pain
  • withdrawal syndrome
  • acute respiratory distress syndrome
  • breast tenderness
  • delirium
  • depression
  • gamma-glutamyltransferase increased
5 - 10 years:
  • peripheral neuropathy
  • back pain
  • depression
  • drug ineffective
  • feeling abnormal
  • increased appetite
  • joint swelling
  • local swelling
  • overdose
  • overweight
10+ years:
  • loss of libido
  • weight increased
  • abasia
  • abdominal bloating
  • abdominal pain aggravated
  • activities of daily living impaired
  • aldolase increased
  • cataract
  • chest pain
  • constipation
not specified:
  • pain
  • nausea
  • drug ineffective
  • pain in extremity
  • dizziness
  • fatigue
  • pneumonia
  • somnolence
  • depression
  • weight increased

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • drug ineffective
  • fatigue
  • somnolence
  • weight increased
  • pain in extremity
  • headache
  • dizziness
  • pneumonia aspiration
male:
  • pain
  • nausea
  • drug ineffective
  • insomnia
  • depression
  • pneumonia
  • anxiety
  • neuropathy peripheral
  • hypoaesthesia
  • weight increased

Most common drug interactions by age *:

10-19:
  • drug ineffective
  • abdominal discomfort
  • abdominal pain
  • abdominal tenderness
  • adverse drug reaction
  • blister
  • blood bilirubin abnormal
  • bone disorder
  • c-reactive protein increased
  • chills
20-29:
  • abortion spontaneous
  • multiple sclerosis
  • sleep disorder
  • suicidal ideation
  • tremor
  • hypoaesthesia
  • fatigue
  • headache
  • insomnia
  • pain of skin
30-39:
  • pain
  • feeling abnormal
  • drug withdrawal syndrome
  • headache
  • nausea
  • weight increased
  • arthralgia
  • accidental poisoning
  • drug ineffective
  • insomnia
40-49:
  • pneumonia
  • bronchitis
  • depression
  • cystitis
  • cystitis haemorrhagic
  • hip arthroplasty
  • pneumonia aspiration
  • urinary bladder haemorrhage
  • pain
  • urinary tract infection
50-59:
  • pain
  • weight increased
  • drug ineffective
  • nausea
  • paraesthesia
  • somnolence
  • dizziness
  • arthralgia
  • fatigue
  • feeling abnormal
60+:
  • pain
  • pain in extremity
  • nausea
  • dyspnoea
  • anxiety
  • back pain
  • osteoarthritis
  • somnolence
  • gastrooesophageal reflux disease
  • pneumonia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Nortriptyline hydrochloride (nortriptyline hydrochloride) is often used to treat depression. Pregabalin (pregabalin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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