Review: taking Nortriptyline hydrochloride and Pregabalin together


Summary

Drug interactions are reported among people who take Nortriptyline hydrochloride and Pregabalin together. This review analyzes the effectiveness and drug interactions between Nortriptyline hydrochloride and Pregabalin. It is created by eHealthMe based on reports of 512 people who take the same drugs from FDA and social media, and is updated regularly.

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Nortriptyline Hydrochloride

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in depression. (latest outcomes from Nortriptyline hydrochloride 1,499 users)

Pregabalin

Pregabalin has active ingredients of pregabalin. It is often used in pain. (latest outcomes from Pregabalin 4,408 users)

On Jul, 21, 2016

512 people who take Nortriptyline Hydrochloride, Pregabalin are studied.


Number of reports submitted per year:

Nortriptyline hydrochloride and Pregabalin drug interactions.

Drug effectiveness over time:

Nortriptyline Hydrochloride:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 28.0% - (2 of 7 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Pregabalin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 60.0% - (3 of 5 people)
  • 6 - 12 months: 16.0% - (1 of 6 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 37.0% - (3 of 8 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Nortriptyline Hydrochloride:
  • female: 33.0% - (6 of 18 people)
  • male: 30.0% - (4 of 13 people)
Pregabalin:
  • female: 27.0% - (5 of 18 people)
  • male: 33.0% - (4 of 12 people)

Drug effectiveness by age:

Nortriptyline Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 55.0% - (5 of 9 people)
  • 60+: 37.0% - (3 of 8 people)
Pregabalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 50.0% - (4 of 8 people)
  • 60+: 0.0% - (0 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • weight increased
  • cardiac failure
  • oedema peripheral
  • rhabdomyolysis
  • feeling abnormal
  • incontinence
  • pain
  • vomiting
  • abdominal pain upper
1 - 6 months:
  • weight increased
  • pain
  • depression
  • dizziness
  • nausea
  • balance disorder
  • cardiac failure
  • oedema peripheral
  • vomiting
  • abdominal distension
6 - 12 months:
  • pain
  • weight increased
  • cerebral infarction
  • intestinal obstruction
  • pain in extremity
  • hypertension
  • mouth dry aggravated
  • photosensitivity reaction
  • urine phosphate abnormal
  • abdominal pain upper
1 - 2 years:
  • vision blurred
  • chest pain
  • constipation
  • drug ineffective
  • insomnia
  • pain
  • weight increased
  • activities of daily living impaired
  • anxiety
  • balance disorder
2 - 5 years:
  • diabetes mellitus
  • pancreatitis
  • withdrawal syndrome
  • breast tenderness
  • mouth dry aggravated
  • stuttering
  • blood testosterone decreased
  • bone and joint pain
  • chest pain
  • constipation aggravated
5 - 10 years:
  • peripheral neuropathy
  • weight above normal
10+ years:
  • loss of libido
  • abdominal bloating
  • abdominal pain aggravated
  • aldolase increased
  • cataract
  • chest pain
  • constipation
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue - chronic
  • increased tendency to bruise
not specified:
  • pain
  • nausea
  • pain in extremity
  • arthralgia
  • pain in jaw
  • osteoarthritis
  • anxiety
  • depression
  • fatigue
  • hypoaesthesia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • pain in extremity
  • headache
  • arthralgia
  • weight increased
  • fall
  • paraesthesia
  • drug ineffective
male:
  • pain
  • nausea
  • insomnia
  • anxiety
  • depression
  • pneumonia
  • hypoaesthesia
  • neuropathy peripheral
  • decreased appetite
  • chronic obstructive pulmonary disease

Most common drug interactions by age *:

10-19:
  • blister
  • crying
  • malaise
  • mood altered
20-29:
  • multiple sclerosis
  • fatigue
  • pain of skin
  • skin burning sensation
  • hypoaesthesia
  • hypoglycaemia
  • insomnia
  • sleep disorder
  • suicidal ideation
  • tremor
30-39:
  • pain
  • weight increased
  • arthralgia
  • insomnia
  • sensory disturbance
  • accident at work
  • anger
  • blood creatinine increased
  • cervicobrachial syndrome
  • depression
40-49:
  • oedema peripheral
  • fatigue
  • vision blurred
  • pain
  • fall
  • diplopia
  • amnesia
  • confusional state
  • immune reconstitution syndrome
  • memory impairment
50-59:
  • nausea
  • pain
  • weight increased
  • pain in jaw
  • headache
  • cardiac failure
  • paraesthesia
  • drug ineffective
  • arthralgia
  • diabetes mellitus
60+:
  • pain
  • nausea
  • anxiety
  • osteoarthritis
  • dyspnoea
  • pain in extremity
  • back pain
  • decreased interest
  • pain in jaw
  • pneumonia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Nortriptyline hydrochloride (nortriptyline hydrochloride) is often used to treat depression. Pregabalin (pregabalin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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