Review: taking Omeprazole and Metformin together


Summary

Drug interactions are reported among people who take Omeprazole and Metformin together. This review analyzes the effectiveness and drug interactions between Omeprazole and Metformin. It is created by eHealthMe based on reports of 11,574 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Omeprazole and Metformin >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Omeprazole 107,016 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

On Aug, 19, 2016

11,574 people who take Omeprazole, Metformin are studied.


Number of reports submitted per year:

Omeprazole and Metformin drug interactions.

Drug effectiveness over time:

Omeprazole:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 54.0% - (13 of 24 people)
  • 6 - 12 months: 53.0% - (14 of 26 people)
  • 1 - 2 years: 75.0% - (25 of 33 people)
  • 2 - 5 years: 65.0% - (47 of 72 people)
  • 5 - 10 years: 79.0% - (49 of 62 people)
  • 10+ years: 83.0% - (26 of 31 people)
  • not specified: 0.0% - (0 of 1 people)
Metformin:
  • < 1 month: 30.0% - (4 of 13 people)
  • 1 - 6 months: 25.0% - (5 of 20 people)
  • 6 - 12 months: 37.0% - (9 of 24 people)
  • 1 - 2 years: 39.0% - (21 of 53 people)
  • 2 - 5 years: 45.0% - (30 of 66 people)
  • 5 - 10 years: 46.0% - (22 of 47 people)
  • 10+ years: 50.0% - (16 of 32 people)
  • not specified: 66.0% - (2 of 3 people)

Drug effectiveness by gender:

Omeprazole:
  • female: 67.0% - (97 of 143 people)
  • male: 69.0% - (79 of 114 people)
Metformin:
  • female: 41.0% - (59 of 142 people)
  • male: 43.0% - (50 of 116 people)

Drug effectiveness by age:

Omeprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 75.0% - (3 of 4 people)
  • 30-39: 73.0% - (19 of 26 people)
  • 40-49: 73.0% - (33 of 45 people)
  • 50-59: 59.0% - (48 of 81 people)
  • 60+: 72.0% - (73 of 101 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 40.0% - (2 of 5 people)
  • 30-39: 31.0% - (7 of 22 people)
  • 40-49: 47.0% - (21 of 44 people)
  • 50-59: 38.0% - (32 of 83 people)
  • 60+: 45.0% - (47 of 104 people)

Most common drug interactions over time *:

< 1 month:
  • alanine aminotransferase increased
  • nausea
  • renal failure acute
  • dizziness
  • pyrexia
  • general physical health deterioration
  • antipsychotic drug level increased
  • cardiovascular disorder
  • cholangitis
  • diarrhoea
1 - 6 months:
  • renal failure acute
  • constipation
  • nausea
  • idiopathic thrombocytopenic purpura
  • respiratory distress
  • upper gastrointestinal haemorrhage
  • chest pain
  • neutropenia
  • cough
  • pneumonia
6 - 12 months:
  • renal failure acute
  • diarrhoea
  • liver function test abnormal
  • arteriosclerosis coronary artery
  • cardiac failure congestive
  • myocardial infarction
  • rash
  • renal failure
  • drug administration error
  • gas - flatulence
1 - 2 years:
  • erectile dysfunction
  • low platelet count
  • nausea
  • pain
  • pancreatitis acute
  • cholelithiasis
  • insomnia
  • vomiting
  • anaemia
  • deep vein thrombosis
2 - 5 years:
  • anxiety
  • myocardial infarction
  • diarrhoea
  • renal failure acute
  • pain
  • hypocalcaemia
  • lactic acidosis
  • tetany
  • insomnia
  • nausea
5 - 10 years:
  • diarrhoea
  • metabolic acidosis
  • renal failure acute
  • cardiac failure congestive
  • depression
  • hypomagnesaemia
  • tetany
  • back pain
  • nausea
  • hypocalcaemia
10+ years:
  • hyperkalaemia
  • renal tubular acidosis
  • diarrhoea
  • lactic acidosis
  • syncope
  • hypotension
  • renal impairment
  • low platelet count
  • metabolic acidosis
  • renal failure acute
not specified:
  • nausea
  • dyspnoea
  • pain
  • diarrhoea
  • vomiting
  • fatigue
  • dizziness
  • blood glucose increased
  • chest pain
  • weight decreased

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • pain
  • diarrhoea
  • vomiting
  • headache
  • fatigue
  • dizziness
  • weight decreased
  • blood glucose increased
male:
  • nausea
  • dyspnoea
  • diarrhoea
  • pain
  • myocardial infarction
  • fatigue
  • renal failure acute
  • asthenia
  • chest pain
  • blood glucose increased

Most common drug interactions by age *:

0-1:
  • arthritis
  • hypertension
  • blood cholesterol increased
  • cerebrovascular accident
  • convulsion
  • diabetic neuropathy
  • dyspnoea
  • foetal exposure during pregnancy
  • haematochezia
  • hypercalcaemia
2-9:
  • lactic acidosis
  • abdominal pain
  • abdominal rigidity
  • abdominal tenderness
  • abnormal behaviour
  • acidosis
  • blood creatinine increased
  • blood glucose increased
  • blood urea increased
  • drug ineffective
10-19:
  • abdominal pain
  • cholecystitis chronic
  • gallbladder disorder
  • biliary dyskinesia
  • weight increased
  • pain
  • vomiting
  • gastric disorder
  • injury
  • irritable bowel syndrome
20-29:
  • pain
  • injury
  • nausea
  • cholecystitis chronic
  • anxiety
  • cholelithiasis
  • vomiting
  • abdominal distension
  • abdominal pain upper
  • deep vein thrombosis
30-39:
  • agitation
  • white blood cell count increased
  • neutrophil count increased
  • coma scale abnormal
  • overdose
  • nausea
  • diabetes mellitus
  • pain
  • type 2 diabetes mellitus
  • dyspnoea
40-49:
  • nausea
  • diabetes mellitus
  • chest pain
  • pain
  • diarrhoea
  • fatigue
  • depression
  • myocardial infarction
  • anxiety
  • headache
50-59:
  • nausea
  • pain
  • depression
  • anxiety
  • dyspnoea
  • diarrhoea
  • fatigue
  • blood glucose increased
  • myocardial infarction
  • vomiting
60+:
  • nausea
  • diarrhoea
  • dyspnoea
  • renal failure acute
  • vomiting
  • asthenia
  • dizziness
  • pain
  • fatigue
  • weight decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Omeprazole and Metformin?

Can you answer these questions?

More questions for: Omeprazole, Metformin

You may be interested in these reviews

More reviews for: Omeprazole, Metformin

On eHealthMe, Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.