Review: taking Omeprazole and Synthroid together


Summary

Drug interactions are reported among people who take Omeprazole and Synthroid together. This review analyzes the effectiveness and drug interactions between Omeprazole and Synthroid. It is created by eHealthMe based on reports of 27,254 people who take the same drugs from FDA and social media, and is updated regularly.

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Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Omeprazole 154,416 users)

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 133,829 users)

On Sep, 18, 2016

27,254 people who take Omeprazole, Synthroid are studied.


Number of reports submitted per year:

Omeprazole and Synthroid drug interactions.

Drug effectiveness over time:

Omeprazole:
  • < 1 month: 33.0% - (11 of 33 people)
  • 1 - 6 months: 40.0% - (29 of 71 people)
  • 6 - 12 months: 41.0% - (21 of 51 people)
  • 1 - 2 years: 51.0% - (42 of 81 people)
  • 2 - 5 years: 61.0% - (84 of 136 people)
  • 5 - 10 years: 65.0% - (69 of 105 people)
  • 10+ years: 65.0% - (41 of 63 people)
  • not specified: 25.0% - (1 of 4 people)
Synthroid:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 26.0% - (8 of 30 people)
  • 6 - 12 months: 48.0% - (15 of 31 people)
  • 1 - 2 years: 44.0% - (24 of 54 people)
  • 2 - 5 years: 57.0% - (57 of 99 people)
  • 5 - 10 years: 61.0% - (74 of 121 people)
  • 10+ years: 71.0% - (143 of 199 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Omeprazole:
  • female: 54.0% - (243 of 447 people)
  • male: 56.0% - (55 of 97 people)
Synthroid:
  • female: 59.0% - (265 of 444 people)
  • male: 60.0% - (59 of 97 people)

Drug effectiveness by age:

Omeprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (2 of 4 people)
  • 20-29: 72.0% - (8 of 11 people)
  • 30-39: 50.0% - (23 of 46 people)
  • 40-49: 55.0% - (54 of 98 people)
  • 50-59: 56.0% - (84 of 148 people)
  • 60+: 53.0% - (127 of 237 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 63.0% - (7 of 11 people)
  • 30-39: 61.0% - (27 of 44 people)
  • 40-49: 53.0% - (54 of 101 people)
  • 50-59: 62.0% - (91 of 145 people)
  • 60+: 60.0% - (145 of 238 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • gastrointestinal perforation
  • nausea
  • cellulitis
  • hypothyroidism postoperative
  • joint pain
  • gastrooesophageal reflux disease
  • drug ineffective
  • peritonitis
  • appendicitis
1 - 6 months:
  • fatigue
  • nausea
  • abdominal pain
  • pain
  • dizziness
  • myalgia
  • agitation
  • constipation
  • diarrhoea
  • dyspnoea
6 - 12 months:
  • back pain
  • dizziness
  • gastrooesophageal reflux disease
  • feeling cold
  • headache
  • itching
  • lethargy
  • death
  • dyspnoea
  • nausea
1 - 2 years:
  • dizziness
  • nausea
  • bone disorder
  • pain
  • anxiety
  • headache
  • fatigue
  • depression
  • dyspnoea
  • paraesthesia
2 - 5 years:
  • cellulitis
  • joint pain
  • hypothyroidism postoperative
  • fatigue
  • nausea
  • gastrointestinal haemorrhage
  • dyspnoea
  • gastrooesophageal reflux disease
  • pain
  • chest pain
5 - 10 years:
  • fatigue
  • depression
  • pain
  • constipation
  • gastrooesophageal reflux disease
  • malaise
  • osteoarthritis
  • weight gain
  • diarrhoea
  • dizziness
10+ years:
  • constipation
  • dizziness
  • depression
  • insomnia
  • nausea
  • lightheadedness - dizzy
  • weight gain
  • diarrhoea
  • headache - mixed tension migraine
  • blood cholesterol increased
not specified:
  • nausea
  • fatigue
  • dyspnoea
  • pain
  • diarrhoea
  • drug ineffective
  • fall
  • asthenia
  • dizziness
  • vomiting

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • pain
  • dyspnoea
  • diarrhoea
  • drug ineffective
  • fall
  • vomiting
  • dizziness
  • headache
male:
  • fatigue
  • nausea
  • dyspnoea
  • drug ineffective
  • diarrhoea
  • asthenia
  • dizziness
  • fall
  • pain
  • pneumonia

Most common drug interactions by age *:

0-1:
  • upper respiratory tract infection
  • vomiting
  • death
  • diarrhoea
  • wheezing
  • ankyloglossia congenital
  • croup infectious
  • ear infection
  • gait disturbance
  • jaundice neonatal
2-9:
  • hypertension
  • hypotension
  • bronchitis
  • cytomegalovirus viraemia
  • diarrhoea
  • dyskinesia
  • eye discharge
  • gastrointestinal hypermotility
  • hyperkalaemia
  • pneumonia aspiration
10-19:
  • pyrexia
  • pain
  • vomiting
  • headache
  • nausea
  • malaise
  • diarrhoea
  • hypertension
  • depression
  • abdominal pain upper
20-29:
  • pain
  • anxiety
  • injury
  • pyrexia
  • deep vein thrombosis
  • nausea
  • drug ineffective
  • fatigue
  • pulmonary embolism
  • abdominal pain
30-39:
  • pain
  • nausea
  • depression
  • anxiety
  • fatigue
  • vomiting
  • arthralgia
  • dyspnoea
  • abdominal pain
  • drug ineffective
40-49:
  • nausea
  • diarrhoea
  • fatigue
  • chest pain
  • pain
  • vomiting
  • headache
  • dyspnoea
  • dizziness
  • pyrexia
50-59:
  • nausea
  • pain
  • fatigue
  • drug ineffective
  • dyspnoea
  • headache
  • anxiety
  • diarrhoea
  • vomiting
  • fall
60+:
  • nausea
  • fatigue
  • dyspnoea
  • diarrhoea
  • fall
  • asthenia
  • dizziness
  • pain
  • drug ineffective
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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