Oxycodone hydrochloride and Benadryl drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Oxycodone hydrochloride and Benadryl together. This review analyzes the effectiveness and drug interactions between Oxycodone hydrochloride and Benadryl. It is created by eHealthMe based on reports of 3,705 people who take the same drugs from FDA, and is updated regularly.

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Oxycodone Hydrochloride

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycodone hydrochloride 1,926 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 44,719 users)

On Jan, 24, 2017

3,705 people who take Oxycodone Hydrochloride, Benadryl are studied.


Number of reports submitted per year:

Oxycodone hydrochloride and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  • nausea
  • diarrhoea
  • pyrexia
  • vomiting
  • febrile neutropenia
  • pain
  • fatigue
  • malaise
  • dyspnoea
  • constipation
1 - 6 months:
  • pain
  • anxiety
  • constipation
  • febrile neutropenia
  • drug dependence
  • drug withdrawal syndrome
  • nausea
  • cellulitis
  • abdominal pain
  • bacteraemia
6 - 12 months:
  • anxiety
  • fall
  • somnolence
  • drug withdrawal syndrome
  • headache
  • memory impairment
  • nausea
  • asthenia
  • coma
  • disturbance in attention
1 - 2 years:
  • drug dependence
  • coma
  • cardiac arrest
  • contusion
  • coronary artery atherosclerosis
  • hepatic fibrosis
  • hepatic steatosis
  • nausea
  • pyrexia
  • respiratory failure
2 - 5 years:
  • drug dependence
  • drug withdrawal syndrome
  • anxiety
  • headache
  • nausea
  • pain
  • depression
  • drug ineffective
  • irritability
  • confusional state
5 - 10 years:
  • depression
  • pain
  • drug withdrawal syndrome
  • headache
  • hyperhidrosis
  • insomnia
  • irritability
  • nervousness
  • oedema peripheral
  • pain in extremity
10+ years:
  • abdominal pain
  • accidental overdose
  • agitation
  • anxiety
  • azotaemia
  • cellulitis
  • cholecystitis
  • chronic obstructive pulmonary disease
  • confusional state
  • deep vein thrombosis
not specified:
  • pain
  • nausea
  • vomiting
  • anxiety
  • fatigue
  • diarrhoea
  • back pain
  • dyspnoea
  • arthralgia
  • pyrexia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • vomiting
  • dyspnoea
  • fatigue
  • diarrhoea
  • arthralgia
  • back pain
  • pyrexia
male:
  • pain
  • nausea
  • vomiting
  • anxiety
  • diarrhoea
  • headache
  • fatigue
  • drug abuse
  • back pain
  • pyrexia

Most common drug interactions by age *:

0-1:
  • constipation
  • decreased appetite
  • diabetes insipidus
  • hyponatraemia
  • muscle spasms
  • myoclonic epilepsy
  • pain
  • vomiting
  • dehydration
  • hypernatraemia
2-9:
  • febrile neutropenia
  • respiratory arrest
  • accidental drug intake by child
  • cardiac arrest
  • mucosal inflammation
  • hypokalaemia
  • neutropenia
  • anaemia
  • leukopenia
  • thrombocytopenia
10-19:
  • pyrexia
  • alanine aminotransferase increased
  • vomiting
  • pain
  • aspartate aminotransferase increased
  • blood culture positive
  • chills
  • disease progression
  • headache
  • hypokalaemia
20-29:
  • drug abuse
  • death
  • pain
  • cardiac arrest
  • anxiety
  • completed suicide
  • diarrhoea
  • nausea
  • respiratory arrest
  • pulmonary embolism
30-39:
  • drug abuse
  • fatigue
  • pain
  • vomiting
  • pyrexia
  • nausea
  • back pain
  • diarrhoea
  • arthralgia
  • dyspnoea
40-49:
  • pain
  • anxiety
  • nausea
  • vomiting
  • headache
  • diarrhoea
  • drug dependence
  • drug withdrawal syndrome
  • drug ineffective
  • abdominal pain
50-59:
  • pain
  • nausea
  • anxiety
  • fall
  • pyrexia
  • vomiting
  • diarrhoea
  • osteoarthritis
  • osteonecrosis of jaw
  • dyspnoea
60+:
  • nausea
  • pain
  • vomiting
  • fatigue
  • dyspnoea
  • pyrexia
  • arthralgia
  • diarrhoea
  • pneumonia
  • constipation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Oxycodone hydrochloride and Benadryl?

Interactions between Oxycodone hydrochloride and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Benadryl and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Oxycodone hydrochloride (oxycodone hydrochloride) is often used to treat pain. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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