Review: taking Oxycontin and Melatonin together


Summary

Drug interactions are reported among people who take Oxycontin and Melatonin together. This review analyzes the effectiveness and drug interactions between Oxycontin and Melatonin. It is created by eHealthMe based on reports of 184 people who take the same drugs from FDA and social media, and is updated regularly.

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Oxycontin

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycontin 49,032 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 4,179 users)

On Aug, 18, 2016

184 people who take Oxycontin, Melatonin are studied.


Number of reports submitted per year:

Oxycontin and Melatonin drug interactions.

Drug effectiveness over time:

Oxycontin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Oxycontin:
  • female: 50.0% - (2 of 4 people)
  • male: 50.0% - (1 of 2 people)
Melatonin:
  • female: 25.0% - (1 of 4 people)
  • male: 100.0% - (2 of 2 people)

Drug effectiveness by age:

Oxycontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • abdominal pain
  • arthralgia
  • fluid retention
  • gastrointestinal hypomotility
  • hyperhidrosis
  • loss of consciousness
  • oedema peripheral
  • overdose
  • pericarditis
  • unresponsive to stimuli
1 - 6 months:
  • drug screen false positive
  • pericarditis
6 - 12 months:
  • bone and joint pain
  • drug screen false positive
  • fatigue - chronic
  • trigeminal neuralgia
1 - 2 years:
  • diarrhoea
  • foot, leg, and ankle swelling
  • gas - belching
2 - 5 years:
  • abdominal pain
  • bone and joint pain
  • fatigue - chronic
  • trigeminal neuralgia
5 - 10 years:
  • diarrhoea
  • foot, leg, and ankle swelling
  • gas - belching
not specified:
  • pain
  • constipation
  • headache
  • bone disorder
  • dyspnoea
  • asthenia
  • fatigue
  • nausea
  • oedema peripheral
  • tooth extraction

Most common drug interactions by gender *:

female:
  • pain
  • headache
  • constipation
  • bone disorder
  • vomiting
  • dyspnoea
  • asthenia
  • deep vein thrombosis
  • oedema peripheral
  • osteonecrosis of jaw
male:
  • nausea
  • fatigue
  • oedema peripheral
  • pruritus
  • skin burning sensation
  • headache
  • myalgia
  • general physical health deterioration
  • pain in extremity
  • back pain

Most common drug interactions by age *:

10-19:
  • headache
  • nausea
  • vomiting
  • constipation
  • abdominal pain
  • bone disorder
  • fatigue
  • gastritis
  • impaired healing
  • dehydration
20-29:
  • small intestinal obstruction
  • asthenia
  • pain
  • actinomyces test positive
  • acute psychosis
  • amnesia
  • bone disorder
  • breath odour
  • candidiasis
  • cellulitis
30-39:
  • fatigue
  • abdominal pain
  • infection
  • nausea
  • sepsis
  • pericarditis
  • abnormal dreams
  • arthralgia
  • asthenia
  • bladder disorder
40-49:
  • pain
  • arthralgia
  • headache
  • pruritus
  • depression
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • cardiac disorder
  • cerebral artery embolism
  • cerebral cyst
50-59:
  • oedema peripheral
  • general physical health deterioration
  • nausea
  • pain
  • pruritus
  • skin burning sensation
  • deformity
  • dry skin
  • joint stiffness
  • myalgia
60+:
  • pain
  • anxiety
  • nausea
  • bone disorder
  • dysgeusia
  • fatigue
  • gingivitis
  • loose tooth
  • metastases to liver
  • oedema peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Oxycontin (oxycodone hydrochloride) is often used to treat pain. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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