Review: taking Paxil and Hydroxyzine together


Summary

Drug interactions are reported among people who take Paxil and Hydroxyzine together. This review analyzes the effectiveness and drug interactions between Paxil and Hydroxyzine. It is created by eHealthMe based on reports of 1,238 people who take the same drugs from FDA and social media, and is updated regularly.

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Paxil

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. (latest outcomes from Paxil 72,492 users)

Hydroxyzine

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in itching. (latest outcomes from Hydroxyzine 9,090 users)

On Aug, 20, 2016

1,238 people who take Paxil, Hydroxyzine are studied.


Number of reports submitted per year:

Paxil and Hydroxyzine drug interactions.

Drug effectiveness over time:

Paxil:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 75.0% - (3 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Hydroxyzine:
  • < 1 month: 0.0% - (0 of 8 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Paxil:
  • female: 46.0% - (6 of 13 people)
  • male: 20.0% - (1 of 5 people)
Hydroxyzine:
  • female: 35.0% - (5 of 14 people)
  • male: 0.0% - (0 of 4 people)

Drug effectiveness by age:

Paxil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 100.0% - (3 of 3 people)
  • 60+: 0.0% - (0 of 0 people)
Hydroxyzine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • anaemia
  • coma
  • neutropenia
  • suicide attempt
  • vomiting
  • dizziness
  • leukopenia
  • multiple drug overdose intentional
  • chest pain
1 - 6 months:
  • completed suicide
  • apathy
  • self esteem decreased
  • nausea
  • alopecia
  • fatigue
  • gastrointestinal haemorrhage
  • diarrhoea
  • idiopathic thrombocytopenic purpura
  • malaise
6 - 12 months:
  • dextrocardia
  • foetal exposure during pregnancy
  • pulmonary aplasia
  • renal dysplasia
  • pulmonary hypoplasia
  • vacterl syndrome
  • congenital pulmonary hypertension
  • asthma
  • failure to thrive
  • gross motor delay
1 - 2 years:
  • fall
  • drug withdrawal syndrome
  • complications of maternal exposure to therapeutic drugs
  • drug exposure during pregnancy
  • maternal drugs affecting foetus
  • somnolence
  • suicidal ideation
  • craniocerebral injury
  • electroencephalogram abnormal
  • hiv test positive
2 - 5 years:
  • chest pain
  • dizziness
  • drug exposure during pregnancy
  • blood alkaline phosphatase increased
  • dyspnoea
  • headache
  • pain
  • abdominal pain
  • acute sinusitis
  • alopecia
5 - 10 years:
  • drug exposure during pregnancy
  • cardiac murmur
  • atrial septal defect
  • patent ductus arteriosus
  • pulmonary artery stenosis congenital
  • aortic stenosis
  • aortic valve incompetence
  • bicuspid aortic valve
  • chest pain
  • congenital anomaly
10+ years:
  • abdominal pain
  • foot deformity
  • back pain
  • cardiac disorder
  • cardiomegaly
  • cerebral palsy
  • drug exposure during pregnancy
  • gait disturbance
  • hyperreflexia
  • peroneal nerve palsy
not specified:
  • anxiety
  • back pain
  • diabetes mellitus
  • depression
  • pain
  • type 2 diabetes mellitus
  • nausea
  • osteoarthritis
  • dyspnoea
  • hypoaesthesia

Most common drug interactions by gender *:

female:
  • back pain
  • anxiety
  • pain
  • depression
  • osteoarthritis
  • nausea
  • dyspnoea
  • diabetes mellitus
  • dizziness
  • type 2 diabetes mellitus
male:
  • type 2 diabetes mellitus
  • drug exposure during pregnancy
  • diabetes mellitus
  • suicidal ideation
  • chest pain
  • fall
  • patent ductus arteriosus
  • anxiety
  • depression
  • asthma

Most common drug interactions by age *:

0-1:
  • chronic obstructive pulmonary disease
  • foetal exposure during pregnancy
  • talipes
2-9:
  • dystonia
  • tardive dyskinesia
10-19:
  • suicide attempt
  • somnolence
  • aggression
  • agitation
  • alanine aminotransferase increased
  • anxiety
  • aspartate aminotransferase increased
  • drug toxicity
  • gamma-glutamyltransferase increased
  • interstitial lung disease
20-29:
  • neuropathy peripheral
  • overdose
  • anxiety
  • type 2 diabetes mellitus
  • arthralgia
  • drug exposure during pregnancy
  • dyspnoea
  • palpitations
  • hodgkin's disease
  • impetigo
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • hypertension
  • neuropathy peripheral
  • diabetic neuropathy
  • post-traumatic stress disorder
  • back pain
  • blood cholesterol increased
  • panic attack
  • palpitations
40-49:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • back pain
  • chest pain
  • anxiety
  • nausea
  • weight increased
  • depression
  • fall
  • suicidal ideation
50-59:
  • anxiety
  • back pain
  • nausea
  • pain
  • pyrexia
  • dehydration
  • depression
  • diverticulum
  • anaemia
  • diarrhoea
60+:
  • anxiety
  • bone disorder
  • pain
  • osteoarthritis
  • back pain
  • spinal osteoarthritis
  • emotional distress
  • pain in jaw
  • dyspnoea
  • bone pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Paxil (paroxetine hydrochloride) is often used to treat depression. Hydroxyzine (hydroxyzine hydrochloride) is often used to treat itching. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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