Review: taking Penicillin and Methotrexate together


Summary

Drug interactions are reported among people who take Penicillin and Methotrexate together. This review analyzes the effectiveness and drug interactions between Penicillin and Methotrexate. It is created by eHealthMe based on reports of 33 people who take the same drugs from FDA and social media, and is updated regularly.

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Penicillin

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. (latest outcomes from Penicillin 1,037 users)

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,047 users)

On Jul, 27, 2016

33 people who take Penicillin, Methotrexate are studied.


Number of reports submitted per year:

Penicillin and Methotrexate drug interactions.

Drug effectiveness over time:

Penicillin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methotrexate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Penicillin:
  • female: 0.0% - (0 of 1 people)
  • male: 0.0% - (0 of 0 people)
Methotrexate:
  • female: 0.0% - (0 of 1 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Penicillin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 1 people)
Methotrexate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • hepatic vein occlusion
  • hyperglycaemia
  • oedema
  • pyrexia
  • renal failure acute
  • c-reactive protein increased
  • cardiac failure
  • arrhythmia
  • febrile neutropenia
  • graft versus host disease
2 - 5 years:
  • malignant melanoma
  • disease recurrence
  • malaise
  • metastases to adrenals
  • metastases to central nervous system
  • metastases to eye
not specified:
  • sepsis
  • abdominal pain
  • acute respiratory distress syndrome
  • bacterial sepsis
  • constipation
  • dermatitis exfoliative
  • drug hypersensitivity
  • hyperchloraemia
  • hypernatraemia
  • hypokalaemia

Most common drug interactions by gender *:

female:
  • graft versus host disease
  • arrhythmia
  • cardiac failure
  • febrile neutropenia
  • hepatic vein occlusion
  • hyperglycaemia
  • blood creatinine increased
  • c-reactive protein increased
  • cardiac failure acute
  • drug hypersensitivity
male:
  • acute respiratory distress syndrome
  • sepsis
  • abdominal pain
  • bacterial sepsis
  • constipation
  • dermatitis exfoliative
  • hyperchloraemia
  • hypernatraemia
  • hypokalaemia
  • hypomagnesaemia

Most common drug interactions by age *:

2-9:
  • acute graft versus host disease
  • cardiac failure
  • hepatic failure
  • histiocytosis haematophagic
  • pulmonary oedema
  • renal failure acute
  • c-reactive protein increased
  • cystitis
  • cytomegalovirus infection
  • pyrexia
10-19:
  • graft versus host disease
  • arrhythmia
  • cardiac failure
  • febrile neutropenia
  • hepatic vein occlusion
  • hyperglycaemia
  • blood creatinine increased
  • c-reactive protein increased
  • cardiac failure acute
  • liver disorder
50-59:
  • sepsis
  • abdominal pain
  • acute respiratory distress syndrome
  • bacterial sepsis
  • constipation
  • dermatitis exfoliative
  • hyperchloraemia
  • hypernatraemia
  • hypokalaemia
  • hypomagnesaemia
60+:
  • cough
  • general physical health deterioration
  • pyrexia
  • cryptogenic organising pneumonia
  • dyspnoea
  • gastric cancer stage iii
  • graft versus host disease in lung
  • interstitial lung disease
  • acute respiratory distress syndrome
  • blood pressure decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Penicillin (penicillin g potassium) is often used to treat strep throat. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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