Review: taking Pepcid and Zantac together


Summary

Drug interactions are reported among people who take Pepcid and Zantac together. This review analyzes the effectiveness and drug interactions between Pepcid and Zantac. It is created by eHealthMe based on reports of 1,933 people who take the same drugs from FDA and social media, and is updated regularly.

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Pepcid

Pepcid has active ingredients of famotidine. It is often used in gastrooesophageal reflux disease. (latest outcomes from Pepcid 27,965 users)

Zantac

Zantac has active ingredients of ranitidine hydrochloride. It is often used in indigestion. (latest outcomes from Zantac 46,871 users)

On Sep, 21, 2016

1,933 people who take Pepcid, Zantac are studied.


Number of reports submitted per year:

Pepcid and Zantac drug interactions.

Drug effectiveness over time:

Pepcid:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Zantac:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Pepcid:
  • female: 0.0% - (0 of 2 people)
  • male: 0.0% - (0 of 0 people)
Zantac:
  • female: 0.0% - (0 of 2 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Pepcid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Zantac:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • leukopenia
  • sepsis
  • lung neoplasm malignant
  • hyperbilirubinaemia
  • dehydration
  • hypotension
  • bk virus infection
  • cystitis haemorrhagic
  • cytomegalovirus infection
1 - 6 months:
  • renal failure acute
  • anaemia
  • cerebral haemorrhage
  • enterocolitis
  • hepatic function abnormal
  • respiratory failure
  • blood lactic acid increased
  • cholecystitis acute
  • fatigue
  • haemoglobin decreased
6 - 12 months:
  • cardiac failure
  • aspartate aminotransferase increased
  • dyspnoea
  • gamma-glutamyltransferase increased
  • alanine aminotransferase increased
  • blood alkaline phosphatase increased
  • blood lactate dehydrogenase increased
  • cardio-respiratory arrest
  • carpal tunnel syndrome
  • depressed level of consciousness
1 - 2 years:
  • osteoporosis
  • bone disorder
  • depression
  • fall
  • leukopenia
  • lower limb fracture
  • multiple fractures
  • arthritis
  • hydronephrosis
  • lymphocele
2 - 5 years:
  • osteoporosis
  • arthritis
  • depression
  • ankle fracture
  • pyrexia
  • calcium deficiency
  • chills
  • dyspepsia
  • dysphagia
  • gastric disorder
5 - 10 years:
  • osteoporosis
  • osteoarthritis
  • bone disorder
  • depression
  • hand fracture
  • intervertebral disc degeneration
  • cerebrovascular accident
  • foot fracture
  • wrist fracture
  • cardiovascular disorder
10+ years:
  • osteoporosis
  • depression
  • ankle fracture
  • vitamin d deficiency
  • anxiety
  • arthritis
  • foot fracture
  • multiple fractures
  • angina pectoris
  • emotional distress
not specified:
  • pain
  • nausea
  • depression
  • fatigue
  • anxiety
  • osteoporosis
  • dyspnoea
  • vomiting
  • bone disorder
  • gastrooesophageal reflux disease

Most common drug interactions by gender *:

female:
  • pain
  • depression
  • osteoporosis
  • nausea
  • vomiting
  • fatigue
  • anxiety
  • fall
  • bone disorder
  • diarrhoea
male:
  • pain
  • anxiety
  • depression
  • dyspnoea
  • nausea
  • pyrexia
  • gastrooesophageal reflux disease
  • fatigue
  • pneumonia
  • constipation

Most common drug interactions by age *:

0-1:
  • pyrexia
  • abdominal distension
  • hypotension
  • multi-organ failure
  • respiratory failure
  • alopecia
  • blister
  • candidiasis
  • cyanosis
  • failure to thrive
2-9:
  • depression
  • multiple fractures
  • osteoporosis
  • osteonecrosis
  • pain in extremity
  • ruptured cerebral aneurysm
  • scoliosis
  • death
  • bone marrow failure
  • foetal exposure during pregnancy
10-19:
  • electrocardiogram qt prolonged
  • pain
  • abdominal pain
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood bilirubin increased
  • pyrexia
  • nausea
  • vomiting
  • depression
20-29:
  • pain
  • vomiting
  • anxiety
  • diarrhoea
  • nausea
  • cholecystitis chronic
  • headache
  • injury
  • jaundice
  • insomnia
30-39:
  • pain
  • convulsion
  • depression
  • anxiety
  • asthenia
  • nausea
  • osteopenia
  • insomnia
  • weight decreased
  • fatigue
40-49:
  • arthralgia
  • nausea
  • depression
  • osteoporosis
  • fatigue
  • pain
  • chest pain
  • arthritis
  • vomiting
  • dyspnoea
50-59:
  • depression
  • pain
  • osteoporosis
  • anxiety
  • dyspnoea
  • fatigue
  • nausea
  • back pain
  • bone disorder
  • osteoarthritis
60+:
  • pain
  • bone disorder
  • nausea
  • anxiety
  • fall
  • dyspnoea
  • chest pain
  • gastrooesophageal reflux disease
  • pyrexia
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Pepcid (famotidine) is often used to treat gastrooesophageal reflux disease. Zantac (ranitidine hydrochloride) is often used to treat indigestion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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