Review: taking Percocet and Skelaxin together


Summary

Drug interactions are reported among people who take Percocet and Skelaxin together. This review analyzes the effectiveness and drug interactions between Percocet and Skelaxin. It is created by eHealthMe based on reports of 693 people who take the same drugs from FDA and social media, and is updated regularly.

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Percocet

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. (latest outcomes from Percocet 29,948 users)

Skelaxin

Skelaxin has active ingredients of metaxalone. It is often used in muscle spasms. (latest outcomes from Skelaxin 6,198 users)

On Aug, 20, 2016

693 people who take Percocet, Skelaxin are studied.


Number of reports submitted per year:

Percocet and Skelaxin drug interactions.

Drug effectiveness over time:

Percocet:
  • < 1 month: 28.0% - (2 of 7 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 40.0% - (2 of 5 people)
  • 1 - 2 years: 57.0% - (4 of 7 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)
Skelaxin:
  • < 1 month: 0.0% - (0 of 7 people)
  • 1 - 6 months: 0.0% - (0 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Percocet:
  • female: 36.0% - (7 of 19 people)
  • male: 44.0% - (4 of 9 people)
Skelaxin:
  • female: 15.0% - (3 of 19 people)
  • male: 12.0% - (1 of 8 people)

Drug effectiveness by age:

Percocet:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 28.0% - (2 of 7 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 40.0% - (2 of 5 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 66.0% - (2 of 3 people)
Skelaxin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 14.0% - (1 of 7 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 20.0% - (1 of 5 people)
  • 50-59: 0.0% - (0 of 5 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • burning sensation
  • coma
  • deafness
  • dizziness
  • multiple sclerosis relapse
  • apnoeic attack
  • back disorder
  • insomnia
  • intervertebral disc protrusion
  • sleep disorder
1 - 6 months:
  • anxiety
  • constipation
  • depression
  • insomnia
  • palpitations
  • abdominal pain
  • accident at work
  • actinic keratosis
  • agitation
  • arthralgia
6 - 12 months:
  • anxiety
  • depression
  • deep vein thrombosis
  • pulmonary embolism
  • abdominal pain
  • abnormal behaviour
  • aggression
  • amnesia
  • constipation
  • diverticular perforation
1 - 2 years:
  • agitation
  • drug withdrawal syndrome
  • dry mouth
  • respiratory distress
  • accidental overdose
  • adjustment disorder with mixed anxiety and depressed mood
  • anxiety
  • bundle branch block left
  • bundle branch block right
  • chills
2 - 5 years:
  • depression
  • fat tissue increased
  • abnormal behaviour
  • adjustment disorder with mixed anxiety and depressed mood
  • confusional state
  • acne
  • aggression
  • alopecia
  • amnesia
  • anxiety
5 - 10 years:
  • cholecystitis chronic
  • gallbladder disorder
  • pain
  • pancreatitis
  • sphincter of oddi dysfunction
not specified:
  • pain
  • anxiety
  • back pain
  • nausea
  • hypertension
  • depression
  • emotional distress
  • arthralgia
  • fatigue
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • back pain
  • hypertension
  • nausea
  • depression
  • emotional distress
  • osteoarthritis
  • pain in extremity
  • fatigue
male:
  • anxiety
  • back pain
  • pain
  • insomnia
  • dyspnoea
  • arthralgia
  • fatigue
  • headache
  • nausea
  • fall

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
10-19:
  • pain
  • cholecystitis chronic
  • weight increased
  • emotional distress
  • gallbladder disorder
  • pancreatitis
  • sphincter of oddi dysfunction
  • abdominal pain upper
  • back pain
  • cholelithiasis
20-29:
  • cholecystitis
  • insomnia
  • back pain
  • blood cholesterol increased
  • bronchitis
  • cardiac failure congestive
  • influenza like illness
  • mass
  • sleep apnoea syndrome
  • supraventricular tachycardia
30-39:
  • anxiety
  • pain
  • bronchitis
  • depression
  • drug withdrawal syndrome
  • arthralgia
  • headache
  • dizziness
  • drug dependence
  • dyspnoea
40-49:
  • pain
  • back pain
  • depression
  • anxiety
  • hypoaesthesia
  • nausea
  • arthralgia
  • muscle spasms
  • oedema peripheral
  • osteomyelitis
50-59:
  • pain
  • fall
  • emotional distress
  • nausea
  • anxiety
  • diarrhoea
  • anaemia
  • fatigue
  • anhedonia
  • hypertension
60+:
  • anxiety
  • pain
  • back pain
  • dyspnoea
  • emotional distress
  • anhedonia
  • fall
  • osteoarthritis
  • osteomyelitis
  • bone disorder

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Percocet (acetaminophen; oxycodone hydrochloride) is often used to treat pain. Skelaxin (metaxalone) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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