Review: taking Phenytoin and Prednisone together


Summary

Drug interactions are reported among people who take Phenytoin and Prednisone together. This review analyzes the effectiveness and drug interactions between Phenytoin and Prednisone. It is created by eHealthMe based on reports of 1,137 people who take the same drugs from FDA and social media, and is updated regularly.

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Phenytoin

Phenytoin has active ingredients of phenytoin. It is often used in convulsion. (latest outcomes from Phenytoin 12,096 users)

Prednisone

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (latest outcomes from Prednisone 176,486 users)

On Aug, 26, 2016

1,137 people who take Phenytoin, Prednisone are studied.


Number of reports submitted per year:

Phenytoin and Prednisone drug interactions.

Drug effectiveness over time:

Phenytoin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Prednisone:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Phenytoin:
  • female: 50.0% - (2 of 4 people)
  • male: 66.0% - (4 of 6 people)
Prednisone:
  • female: 33.0% - (1 of 3 people)
  • male: 66.0% - (2 of 3 people)

Drug effectiveness by age:

Phenytoin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 100.0% - (3 of 3 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 50.0% - (2 of 4 people)
Prednisone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 100.0% - (1 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • cardiac arrest
  • multi-organ failure
  • sepsis
  • fatigue
  • hepatic failure
  • pain
  • pyrexia
  • respiratory failure
  • urinary tract infection
1 - 6 months:
  • cardiac tamponade
  • pericardial effusion
  • cardiac arrest
  • fatigue
  • supraventricular tachycardia
  • weakness
  • disseminated intravascular coagulation
  • stevens-johnson syndrome
  • leukocytosis
  • multi-organ failure
6 - 12 months:
  • thrombocytopenia
  • convulsion
  • toxic epidermal necrolysis
  • cerebrovascular accident
1 - 2 years:
  • nausea
  • dizziness aggravated
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • convulsion
  • pain
  • abdominal pain
  • acute myeloid leukaemia
  • acute sinusitis
  • alopecia
  • anaemia
2 - 5 years:
  • morphoea
  • acute lymphocytic leukaemia
5 - 10 years:
  • numbness and tingling
  • seizure
10+ years:
  • arthritis
  • basal cell carcinoma
  • lupus-like syndrome
  • convulsion
  • drug ineffective
  • drug level decreased
  • dysphemia
  • irritability
  • lipase abnormal
  • movement disorder
not specified:
  • convulsion
  • pain
  • pneumonia
  • nausea
  • fall
  • oedema peripheral
  • pyrexia
  • dyspnoea
  • back pain
  • fatigue

Most common drug interactions by gender *:

female:
  • convulsion
  • pain
  • nausea
  • fall
  • dyspnoea
  • pneumonia
  • asthenia
  • pain in extremity
  • depression
  • pyrexia
male:
  • convulsion
  • pyrexia
  • oedema peripheral
  • pneumonia
  • fatigue
  • pain
  • back pain
  • anaemia
  • anxiety
  • sepsis

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • chronic graft versus host disease
  • convulsion
  • drug toxicity
  • reversible posterior leukoencephalopathy syndrome
  • septic shock
  • stevens-johnson syndrome
  • acute graft versus host disease in intestine
  • ataxia
  • confusion
  • cytomegalovirus viraemia
10-19:
  • chronic graft versus host disease
  • diabetes insipidus
  • haemorrhage intracranial
  • sepsis
  • deafness neurosensory
  • convulsion
  • failure to thrive
  • multi-organ failure
  • cytomegalovirus viraemia
  • death
20-29:
  • pain
  • fatigue
  • nephrogenic systemic fibrosis
  • pyrexia
  • skin tightness
  • cardiac arrest
  • dry skin
  • cardiac tamponade
  • mobility decreased
  • pericardial effusion
30-39:
  • pain
  • arthralgia
  • gait disturbance
  • musculoskeletal stiffness
  • nephrogenic systemic fibrosis
  • pain in extremity
  • pruritus
  • atrophy
  • dry skin
  • joint contracture
40-49:
  • pyrexia
  • convulsion
  • pneumonia
  • hypotension
  • dizziness
  • mucosal inflammation
  • sepsis
  • dehydration
  • oedema peripheral
  • dyspnoea
50-59:
  • convulsion
  • pain
  • fall
  • pneumonia
  • nausea
  • arthralgia
  • anxiety
  • oedema peripheral
  • hypotension
  • anaemia
60+:
  • convulsion
  • back pain
  • pain
  • nausea
  • fall
  • pneumonia
  • pain in extremity
  • confusional state
  • depression
  • oedema peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Phenytoin (phenytoin) is often used to treat convulsion. Prednisone (prednisone) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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