Review: taking Plaquenil and Aspirin together


Summary

Drug interactions are reported among people who take Plaquenil and Aspirin together. This review analyzes the effectiveness and drug interactions between Plaquenil and Aspirin. It is created by eHealthMe based on reports of 1,427 people who take the same drugs from FDA and social media, and is updated regularly.

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Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. (latest outcomes from Plaquenil 15,292 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 160,694 users)

On Jul, 21, 2016

1,427 people who take Plaquenil, Aspirin are studied.


Number of reports submitted per year:

Plaquenil and Aspirin drug interactions.

Drug effectiveness over time:

Plaquenil:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 44.0% - (4 of 9 people)
  • 1 - 2 years: 16.0% - (1 of 6 people)
  • 2 - 5 years: 27.0% - (3 of 11 people)
  • 5 - 10 years: 46.0% - (6 of 13 people)
  • 10+ years: 66.0% - (6 of 9 people)
  • not specified: 0.0% - (0 of 0 people)
Aspirin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 50.0% - (3 of 6 people)
  • 2 - 5 years: 56.0% - (9 of 16 people)
  • 5 - 10 years: 80.0% - (8 of 10 people)
  • 10+ years: 33.0% - (3 of 9 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Plaquenil:
  • female: 43.0% - (20 of 46 people)
  • male: 12.0% - (1 of 8 people)
Aspirin:
  • female: 52.0% - (21 of 40 people)
  • male: 33.0% - (2 of 6 people)

Drug effectiveness by age:

Plaquenil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 55.0% - (5 of 9 people)
  • 40-49: 14.0% - (1 of 7 people)
  • 50-59: 47.0% - (8 of 17 people)
  • 60+: 33.0% - (6 of 18 people)
Aspirin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 88.0% - (8 of 9 people)
  • 40-49: 25.0% - (1 of 4 people)
  • 50-59: 50.0% - (7 of 14 people)
  • 60+: 43.0% - (7 of 16 people)

Most common drug interactions over time *:

< 1 month:
  • anaemia
  • abdominal pain upper
  • alanine aminotransferase increased
  • aortic calcification
  • arthralgia
  • arthropathy
  • asthenia
  • atrial fibrillation
  • bacterial sepsis
  • blood alkaline phosphatase increased
1 - 6 months:
  • pyrexia
  • abscess
  • disseminated intravascular coagulation
  • infection
  • pneumonia necrotising
  • pulmonary haemorrhage
  • respiratory acidosis
  • pneumonia
  • abdominal bloating
  • abdominal pain aggravated
6 - 12 months:
  • ulcer
  • vision blurred
  • dysphagia
  • fatigue
  • nausea
  • arthralgia
  • cardiac failure
  • cardiac valve disease
  • decreased appetite
  • diastolic dysfunction
1 - 2 years:
  • bundle branch block
  • cardiac death
  • coronary artery disease
  • dehydration
  • hypotension
  • left ventricular dysfunction
  • muscle cramps aggravated
  • muscle pain
  • muscle twitching
  • myocardial infarction
2 - 5 years:
  • cellulitis
  • endocarditis bacterial
  • renal failure acute
  • sepsis
  • angina unstable
  • asthenia
  • bradyphrenia
  • hyponatraemia
  • hypotension
  • lightheadedness
5 - 10 years:
  • cellulitis
  • endocarditis bacterial
  • renal failure acute
  • gastrointestinal disorder
  • abdominal pain
  • arteriosclerosis coronary artery
  • asterixis
  • axillary mass
  • benign neoplasm of thyroid gland
  • breast cancer
10+ years:
  • atrial fibrillation
  • gangrene
  • joint pain
  • stroke
  • acute respiratory distress syndrome
  • asthenia
  • atelectasis
  • blood gases abnormal
  • bone and joint pain
  • bronchial secretion retention
not specified:
  • pain
  • nausea
  • arthralgia
  • fatigue
  • oedema peripheral
  • pneumonia
  • diarrhoea
  • fall
  • anxiety
  • asthenia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • arthralgia
  • fall
  • anxiety
  • diarrhoea
  • oedema peripheral
  • pneumonia
  • pain in extremity
male:
  • asthenia
  • oedema peripheral
  • pneumonia
  • pain
  • arthralgia
  • coronary artery disease
  • decreased appetite
  • pleural effusion
  • cardiac failure congestive
  • fatigue

Most common drug interactions by age *:

0-1:
  • bladder diverticulum
  • clostridial infection
  • palatal disorder
  • reflux nephropathy
  • renal hypertrophy
  • respiratory syncytial virus infection
  • urinary tract infection
10-19:
  • parotitis
  • systemic lupus erythematosus
  • renal papillary necrosis
  • anaphylactoid reaction
  • antinuclear antibody positive
  • cardiac arrest
  • cardio-respiratory arrest
  • cyanosis
  • electrocardiogram abnormal
  • electrocardiogram qt prolonged
20-29:
  • pain
  • urinary tract infection
  • systemic lupus erythematosus
  • aggression
  • agitation
  • anaemia
  • anxiety
  • blood creatine phosphokinase increased
  • blood magnesium decreased
  • blood sodium decreased
30-39:
  • anxiety
  • anhedonia
  • arthralgia
  • diarrhoea
  • emotional distress
  • fear
  • injury
  • pain
  • renal failure
  • renal impairment
40-49:
  • pain
  • oedema peripheral
  • arthralgia
  • asthenia
  • drug ineffective
  • fibromyalgia
  • nausea
  • pain in extremity
  • deformity
  • gastrooesophageal reflux disease
50-59:
  • pain
  • fatigue
  • arthralgia
  • oedema peripheral
  • nausea
  • headache
  • diarrhoea
  • fall
  • constipation
  • osteomyelitis
60+:
  • pneumonia
  • pain
  • nausea
  • asthenia
  • fall
  • anxiety
  • fatigue
  • atrial fibrillation
  • dizziness
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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