Review: taking Plaquenil and Ibuprofen together


Summary

Drug interactions are reported among people who take Plaquenil and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Plaquenil and Ibuprofen. It is created by eHealthMe based on reports of 1,560 people who take the same drugs from FDA and social media, and is updated regularly.

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Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. (latest outcomes from Plaquenil 26,922 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 92,738 users)

On Sep, 17, 2016

1,560 people who take Plaquenil, Ibuprofen are studied.


Number of reports submitted per year:

Plaquenil and Ibuprofen drug interactions.

Drug effectiveness over time:

Plaquenil:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 33.0% - (4 of 12 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 1 people)
Ibuprofen:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 20.0% - (2 of 10 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Plaquenil:
  • female: 19.0% - (6 of 31 people)
  • male: 50.0% - (2 of 4 people)
Ibuprofen:
  • female: 32.0% - (11 of 34 people)
  • male: 66.0% - (2 of 3 people)

Drug effectiveness by age:

Plaquenil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 20.0% - (1 of 5 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 33.0% - (2 of 6 people)
  • 50-59: 22.0% - (2 of 9 people)
  • 60+: 20.0% - (1 of 5 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 41.0% - (5 of 12 people)
  • 40-49: 28.0% - (2 of 7 people)
  • 50-59: 37.0% - (3 of 8 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • atrial septal defect
  • neonatal aspiration
  • neonatal respiratory distress syndrome
  • noonan syndrome
  • pulmonary artery stenosis congenital
  • anxiety
  • cleft palate
  • feeling abnormal
  • meningitis aseptic
  • pulmonary valve stenosis congenital
1 - 6 months:
  • fatigue
  • headache
  • dizziness
  • flank pain
  • nausea
  • atrial septal defect
  • neonatal aspiration
  • neonatal respiratory distress syndrome
  • noonan syndrome
  • pulmonary artery stenosis congenital
6 - 12 months:
  • nausea
  • fall
  • pleurisy
  • arthritis
  • blindness
  • cataract
  • chest pain
  • cleft palate
  • contusion
  • dizziness
1 - 2 years:
  • dyspnoea
  • chest pain
  • nausea
  • bronchitis
  • eustachian tube dysfunction
  • otitis media acute
  • pathological gambling
  • pharyngitis
  • psychiatric symptom
  • rhinitis allergic
2 - 5 years:
  • palpitations
  • shortness of breath
  • weight gain
  • angina unstable
  • coronary artery disease
  • dermatitis
  • frequent headaches
  • oral candidiasis
  • renal cyst
  • lethargy
5 - 10 years:
  • atrial fibrillation/flutter
  • chest wall mass
  • deafness
  • decreased appetite
  • deep vein thrombosis
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • general physical health deterioration
  • hair loss
  • headache - tension
  • irregular heartbeat
10+ years:
  • hip arthroplasty
  • adverse event
  • angina pectoris
  • arthritis
  • arthropathy
  • convulsion
  • depression
  • dyspnoea
  • dysuria
  • fall
not specified:
  • nausea
  • headache
  • pain
  • arthralgia
  • drug ineffective
  • fatigue
  • dizziness
  • rheumatoid arthritis
  • vomiting
  • dyspnoea

Most common drug interactions by gender *:

female:
  • nausea
  • headache
  • pain
  • fatigue
  • arthralgia
  • dizziness
  • drug ineffective
  • rheumatoid arthritis
  • vomiting
  • injection site pain
male:
  • dyspnoea
  • nausea
  • myocardial infarction
  • drug ineffective
  • chest pain
  • pain
  • coronary artery disease
  • atrial fibrillation
  • fall
  • insomnia

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • pyloric stenosis
2-9:
  • alopecia
  • back pain
  • c-reactive protein abnormal
  • cerebral oedema
  • csf glucose decreased
  • dysarthria
  • injection site pain
  • lymphocyte count abnormal
  • migraine aggravated
  • mobility decreased
10-19:
  • injection site erythema
  • injection site warmth
  • injection site reaction
  • injection site swelling
  • intentional overdose
  • agitation
  • anxiety
  • feeling abnormal
  • lack of spontaneous speech
  • meningitis aseptic
20-29:
  • pain
  • fatigue
  • nausea
  • rheumatoid arthritis
  • dyspnoea
  • cholecystitis chronic
  • influenza like illness
  • injection site reaction
  • photosensitivity reaction
  • drug ineffective
30-39:
  • pain
  • fatigue
  • nausea
  • headache
  • anxiety
  • dizziness
  • emotional distress
  • pain in extremity
  • stress
  • drug ineffective
40-49:
  • nausea
  • headache
  • vomiting
  • rheumatoid arthritis
  • fatigue
  • pyrexia
  • drug ineffective
  • diarrhoea
  • drug hypersensitivity
  • arthralgia
50-59:
  • headache
  • nausea
  • pain
  • drug ineffective
  • arthralgia
  • dizziness
  • dyspnoea
  • fatigue
  • injection site pain
  • nasopharyngitis
60+:
  • arthralgia
  • fall
  • dyspnoea
  • headache
  • nausea
  • fatigue
  • pain
  • diarrhoea
  • dizziness
  • drug ineffective

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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