Review: taking Plaquenil and Ibuprofen together


Summary

Drug interactions are reported among people who take Plaquenil and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Plaquenil and Ibuprofen. It is created by eHealthMe based on reports of 1,084 people who take the same drugs from FDA and social media, and is updated regularly.

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Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. (latest outcomes from Plaquenil 19,931 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 73,378 users)

On Aug, 26, 2016

1,084 people who take Plaquenil, Ibuprofen are studied.


Number of reports submitted per year:

Plaquenil and Ibuprofen drug interactions.

Drug effectiveness over time:

Plaquenil:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 33.0% - (4 of 12 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 1 people)
Ibuprofen:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 20.0% - (2 of 10 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Plaquenil:
  • female: 19.0% - (6 of 31 people)
  • male: 50.0% - (2 of 4 people)
Ibuprofen:
  • female: 32.0% - (11 of 34 people)
  • male: 66.0% - (2 of 3 people)

Drug effectiveness by age:

Plaquenil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 20.0% - (1 of 5 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 33.0% - (2 of 6 people)
  • 50-59: 22.0% - (2 of 9 people)
  • 60+: 20.0% - (1 of 5 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 41.0% - (5 of 12 people)
  • 40-49: 28.0% - (2 of 7 people)
  • 50-59: 37.0% - (3 of 8 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • atrial septal defect
  • neonatal aspiration
  • neonatal respiratory distress syndrome
  • noonan syndrome
  • pulmonary artery stenosis congenital
  • anxiety
  • cleft palate
  • feeling abnormal
  • meningitis aseptic
  • pulmonary valve stenosis congenital
1 - 6 months:
  • fatigue
  • headache
  • dizziness
  • flank pain
  • nausea
  • atrial septal defect
  • neonatal aspiration
  • neonatal respiratory distress syndrome
  • noonan syndrome
  • pulmonary artery stenosis congenital
6 - 12 months:
  • nausea
  • fall
  • pleurisy
  • arthritis
  • blindness
  • cataract
  • chest pain
  • cleft palate
  • contusion
  • drug toxicity
1 - 2 years:
  • dyspnoea
  • chest pain
  • nausea
  • bronchitis
  • eustachian tube dysfunction
  • otitis media acute
  • pathological gambling
  • pharyngitis
  • psychiatric symptom
  • rhinitis allergic
2 - 5 years:
  • palpitations
  • shortness of breath
  • weight gain
  • frequent headaches
  • angina unstable
  • coronary artery disease
  • dermatitis
  • lethargy
  • myocardial infarction
  • nausea
5 - 10 years:
  • atrial fibrillation/flutter
  • chest wall mass
  • deafness
  • decreased appetite
  • deep vein thrombosis
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • general physical health deterioration
  • hair loss
  • headache - tension
  • irregular heartbeat
10+ years:
  • adverse event
  • angina pectoris
  • arthritis
  • arthropathy
  • convulsion
  • depression
  • dyspnoea
  • dysuria
  • fall
  • femoral neck fracture
not specified:
  • nausea
  • pain
  • headache
  • fatigue
  • arthralgia
  • drug ineffective
  • fall
  • dizziness
  • dyspnoea
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • headache
  • fatigue
  • pain
  • arthralgia
  • dizziness
  • drug ineffective
  • dyspnoea
  • pain in extremity
  • fall
male:
  • nausea
  • dyspnoea
  • chest pain
  • myocardial infarction
  • atrial fibrillation
  • coronary artery disease
  • fall
  • insomnia
  • drug ineffective
  • headache

Most common drug interactions by age *:

2-9:
  • alopecia
  • back pain
  • c-reactive protein abnormal
  • cerebral oedema
  • csf glucose decreased
  • dysarthria
  • injection site pain
  • lymphocyte count abnormal
  • migraine aggravated
  • mobility decreased
10-19:
  • agitation
  • anxiety
  • feeling abnormal
  • injection site erythema
  • lack of spontaneous speech
  • meningitis aseptic
  • mental status changes
  • tremor
  • hypersensitivity
  • intentional overdose
20-29:
  • pain
  • cholecystitis chronic
  • nausea
  • fatigue
  • injury
  • maternal exposure during pregnancy
  • abdominal pain
  • anxiety
  • chest pain
  • cholelithiasis
30-39:
  • pain
  • fatigue
  • nausea
  • anxiety
  • emotional distress
  • stress
  • injury
  • back pain
  • headache
  • systemic lupus erythematosus
40-49:
  • nausea
  • headache
  • pyrexia
  • vomiting
  • fatigue
  • pain
  • diarrhoea
  • dizziness
  • myalgia
  • nephrolithiasis
50-59:
  • headache
  • nausea
  • pain
  • dizziness
  • drug ineffective
  • dyspnoea
  • fatigue
  • muscular weakness
  • arthralgia
  • injection site pain
60+:
  • fall
  • arthralgia
  • dyspnoea
  • diarrhoea
  • fatigue
  • insomnia
  • nausea
  • pain in extremity
  • oedema peripheral
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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