Plaquenil and Naproxen drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Plaquenil and Naproxen together. This review analyzes the effectiveness and drug interactions between Plaquenil and Naproxen. It is created by eHealthMe based on reports of 1,988 people who take the same drugs from FDA, and is updated regularly.

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Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. (latest outcomes from Plaquenil 28,335 users)

Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 38,435 users)

On Feb, 05, 2017

1,988 people who take Plaquenil, Naproxen are studied.


Number of reports submitted per year:

Plaquenil and Naproxen drug interactions.

Most common drug interactions over time *:

< 1 month:
  • rash
  • chest discomfort
  • palpitations
  • vomiting
  • alanine aminotransferase increased
  • arthralgia
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • c-reactive protein increased
  • cough
1 - 6 months:
  • drug ineffective
  • dyspnoea
  • liver function test abnormal
  • cardiac failure congestive
  • arthralgia
  • arthritis
  • impaired work ability
  • joint swelling
  • atrial fibrillation
  • chest discomfort
6 - 12 months:
  • gastrointestinal haemorrhage
  • systemic lupus erythematosus
  • type 2 diabetes mellitus
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • autoimmune hepatitis
  • biliary dilatation
  • blood alkaline phosphatase increased
  • cholestasis
  • colonoscopy
1 - 2 years:
  • atrial fibrillation
  • coronary artery disease
  • thrombophlebitis
  • chest pain
  • dyspnoea
  • cardiac failure congestive
  • disease progression
  • infusion site abscess
  • infusion site induration
  • infusion site infection
2 - 5 years:
  • acute myocardial infarction
  • cardiac failure congestive
  • deep vein thrombosis
  • pleural effusion
  • pulmonary embolism
  • retinal detachment
  • seizure
  • troponin increased
  • ventricular tachycardia
  • alopecia
5 - 10 years:
  • drug ineffective
  • impaired work ability
  • interstitial lung disease
  • red blood cell sedimentation rate abnormal
  • rheumatoid arthritis
  • drug effect decreased
  • biliary dyskinesia
  • cough
  • gallbladder injury
  • malaise
10+ years:
  • blindness
  • carpal tunnel syndrome
  • cataract
  • deafness bilateral
  • drug ineffective
  • fasciitis
  • foot deformity
  • gait disturbance
  • gastric disorder
  • hyperlipidaemia
not specified:
  • drug ineffective
  • pain
  • arthralgia
  • headache
  • nausea
  • rheumatoid arthritis
  • fatigue
  • vomiting
  • dizziness
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • headache
  • nausea
  • rheumatoid arthritis
  • arthralgia
  • fatigue
  • vomiting
  • dizziness
  • pain in extremity
male:
  • drug ineffective
  • arthralgia
  • joint swelling
  • pain
  • dyspnoea
  • rheumatoid arthritis
  • nausea
  • headache
  • pain in extremity
  • pneumonia

Most common drug interactions by age *:

0-1:
  • adrenal insufficiency
  • antibody test positive
  • arthritis
  • bone density decreased
  • c-reactive protein increased
  • diarrhoea
  • dizziness
  • drug ineffective
  • drug intolerance
  • nausea
2-9:
  • abdominal pain upper
  • alopecia
  • asthenia
  • cough
  • rhinorrhoea
  • sneezing
  • c-reactive protein increased
  • pyrexia
  • abdominal pain
  • eating disorder
10-19:
  • nausea
  • drug ineffective
  • pain
  • vomiting
  • diarrhoea
  • body height below normal
  • fatigue
  • heart rate increased
  • rheumatoid arthritis
  • septic shock
20-29:
  • cough
  • pyrexia
  • dizziness
  • fatigue
  • injection site pain
  • diarrhoea
  • hepatic necrosis
  • injection site erythema
  • joint swelling
  • vomiting
30-39:
  • pain
  • arthralgia
  • headache
  • nausea
  • fatigue
  • alopecia
  • depression
  • infusion related reaction
  • malaise
  • pain in extremity
40-49:
  • headache
  • drug ineffective
  • pain
  • pain in extremity
  • rheumatoid arthritis
  • arthralgia
  • injection site pain
  • fatigue
  • anxiety
  • back pain
50-59:
  • drug ineffective
  • rheumatoid arthritis
  • arthralgia
  • pain
  • nausea
  • fatigue
  • headache
  • malaise
  • vomiting
  • dizziness
60+:
  • drug ineffective
  • pain
  • arthralgia
  • fatigue
  • nausea
  • dyspnoea
  • fall
  • headache
  • rheumatoid arthritis
  • rash

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Plaquenil and Naproxen?

Interactions between Plaquenil and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Naproxen and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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