Review: taking Prednisone and Prolia together


Summary

Drug interactions are reported among people who take Prednisone and Prolia together. This review analyzes the effectiveness and drug interactions between Prednisone and Prolia. It is created by eHealthMe based on reports of 1,167 people who take the same drugs from FDA and social media, and is updated regularly.

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Prednisone

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (latest outcomes from Prednisone 224,214 users)

Prolia

Prolia has active ingredients of denosumab. It is often used in osteoporosis post-menopausal. (latest outcomes from Prolia 32,357 users)

On Sep, 17, 2016

1,167 people who take Prednisone, Prolia are studied.


Number of reports submitted per year:

Prednisone and Prolia drug interactions.

Drug effectiveness over time:

Prednisone:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (3 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Prolia:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Prednisone:
  • female: 100.0% - (3 of 3 people)
  • male: 100.0% - (1 of 1 people)
Prolia:
  • female: 0.0% - (0 of 3 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Prednisone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 100.0% - (3 of 3 people)
Prolia:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • hypocalcaemia
  • fatigue
  • pneumonitis
  • paraesthesia
  • oedema peripheral
  • asthenia
  • pain in extremity
  • anaemia
  • arthralgia
  • death
1 - 6 months:
  • osteonecrosis of jaw
  • fatigue
  • cellulitis
  • hypocalcaemia
  • asthenia
  • hepatitis fulminant
  • myalgia
  • pain in extremity
  • back pain
  • decreased appetite
6 - 12 months:
  • osteonecrosis of jaw
  • impaired healing
  • dyspnoea exertional
  • pain
  • arthralgia
  • cataract
  • drug ineffective
  • fatigue
  • liver cirrhosis
  • lymphocyte count decreased
1 - 2 years:
  • osteonecrosis of jaw
  • dehydration
  • chronic obstructive pulmonary disease
  • exposed bone in jaw
  • nausea
  • pain
  • tooth abscess
  • confusional state
  • death
  • hypothyroidism
2 - 5 years:
  • osteonecrosis of jaw
  • pneumonia
  • anaemia
  • altered state of consciousness
  • dehydration
  • encephalopathy
  • hyponatraemia
  • hypotension
  • renal failure acute
  • sepsis
5 - 10 years:
  • liver cirrhosis
  • adverse drug reaction
  • cough
  • death
  • drug ineffective
  • dysphagia
  • fall
  • femur fracture
  • hip fracture
  • impaired healing
not specified:
  • arthralgia
  • pain
  • fatigue
  • dyspnoea
  • pain in extremity
  • back pain
  • asthenia
  • fall
  • nausea
  • cough

Most common drug interactions by gender *:

female:
  • arthralgia
  • pain
  • pain in extremity
  • back pain
  • fatigue
  • fall
  • dyspnoea
  • joint swelling
  • drug ineffective
  • pneumonia
male:
  • fatigue
  • osteonecrosis of jaw
  • dyspnoea
  • malignant neoplasm progression
  • asthenia
  • death
  • decreased appetite
  • nausea
  • weight decreased
  • pain

Most common drug interactions by age *:

10-19:
  • anticonvulsant drug level decreased
  • bone pain
  • constipation
  • convulsion
20-29:
  • constipation
  • abortion induced
  • bone pain
  • cholestasis
  • exposed bone in jaw
  • febrile neutropenia
  • infrequent bowel movements
  • pancreatitis acute
  • pregnancy
  • septic shock
30-39:
  • animal bite
  • arthralgia
  • arthropathy
  • c-reactive protein increased
  • dyspnoea
  • joint swelling
  • migraine
  • osteoporosis
  • pain
  • postoperative wound infection
40-49:
  • renal disorder
  • ureteric stenosis
  • dyspnoea
  • osteonecrosis of jaw
  • arthralgia
  • dehydration
  • diverticulitis
  • muscle spasms
  • gait disturbance
  • headache
50-59:
  • arthralgia
  • pain
  • fall
  • blood cholesterol increased
  • joint swelling
  • pyrexia
  • rash
  • diabetes mellitus
  • drug ineffective
  • pain in extremity
60+:
  • arthralgia
  • fatigue
  • pain
  • pain in extremity
  • dyspnoea
  • back pain
  • asthenia
  • nausea
  • pneumonia
  • cough

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prednisone (prednisone) is often used to treat rheumatoid arthritis. Prolia (denosumab) is often used to treat osteoporosis post-menopausal. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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