Review: taking Prilosec and Flagyl together


Summary

Drug interactions are reported among people who take Prilosec and Flagyl together. This review analyzes the effectiveness and drug interactions between Prilosec and Flagyl. It is created by eHealthMe based on reports of 2,499 people who take the same drugs from FDA and social media, and is updated regularly.

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Prilosec

Prilosec has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Prilosec 58,542 users)

Flagyl

Flagyl has active ingredients of metronidazole. It is often used in crohn's disease. (latest outcomes from Flagyl 10,369 users)

On Jul, 23, 2016

2,499 people who take Prilosec, Flagyl are studied.


Number of reports submitted per year:

Prilosec and Flagyl drug interactions.

Drug effectiveness over time:

Prilosec:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 83.0% - (5 of 6 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 66.0% - (4 of 6 people)
  • 2 - 5 years: 100.0% - (8 of 8 people)
  • 5 - 10 years: 100.0% - (4 of 4 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Flagyl:
  • < 1 month: 41.0% - (7 of 17 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (3 of 3 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Prilosec:
  • female: 71.0% - (15 of 21 people)
  • male: 69.0% - (9 of 13 people)
Flagyl:
  • female: 42.0% - (8 of 19 people)
  • male: 57.0% - (8 of 14 people)

Drug effectiveness by age:

Prilosec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 28.0% - (2 of 7 people)
  • 40-49: 66.0% - (4 of 6 people)
  • 50-59: 71.0% - (5 of 7 people)
  • 60+: 90.0% - (9 of 10 people)
Flagyl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 57.0% - (4 of 7 people)
  • 40-49: 33.0% - (2 of 6 people)
  • 50-59: 28.0% - (2 of 7 people)
  • 60+: 66.0% - (6 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • hypertension
  • pneumonia
  • convulsion
  • clostridium difficile colitis
  • pulmonary oedema
  • international normalised ratio increased
  • colonic pseudo-obstruction
  • blood potassium decreased
  • diarrhoea
1 - 6 months:
  • septic shock
  • hyperkalaemia
  • suicidal ideation
  • escherichia infection
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • abdominal sepsis
  • depression
  • enterococcal infection
  • multi-organ failure
6 - 12 months:
  • thrombocytopenia
  • abdominal pain
  • bacterial infection
  • chest pain
  • clostridium test positive
  • confusional state
  • crohn's disease
  • dehydration
  • dyskinesia
  • enteritis
1 - 2 years:
  • hair loss
  • blood glucose increased
  • insulin resistance
  • lightheadedness - fainting
  • acne cystic
  • acne steroid-induced
  • depression aggravated
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fever
  • headache
2 - 5 years:
  • acute myeloid leukaemia
  • pain
  • anxiety
  • dyspepsia
  • emotional distress
  • general physical health deterioration
  • headache
  • mental status changes
  • abdominal pain upper
  • abnormal behaviour
5 - 10 years:
  • arthritis
  • cramps - leg
  • cramps - muscle
  • diarrhoea
  • dizziness
  • fibromyalgia
  • ibs
  • joint stiffness
  • memory impairment
  • mobility decreased
10+ years:
  • blood creatinine increased
  • intervertebral disc protrusion
  • neuropathy peripheral
  • tarsal tunnel syndrome
  • anaemia
  • anxiety
  • bladder discomfort
  • blood triglycerides decreased
  • blood triglycerides increased
  • bunion
not specified:
  • pain
  • anxiety
  • nausea
  • diarrhoea
  • anaemia
  • osteonecrosis of jaw
  • dyspnoea
  • injury
  • fatigue
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • diarrhoea
  • nausea
  • osteonecrosis of jaw
  • injury
  • abdominal pain
  • dyspnoea
  • anaemia
  • fatigue
male:
  • vomiting
  • pain
  • thrombocytopenia
  • nausea
  • anaemia
  • anxiety
  • pneumonia
  • hypotension
  • asthenia
  • pyrexia

Most common drug interactions by age *:

0-1:
  • disorientation
  • metabolic acidosis
  • myocardial infarction
  • thrombocytopenia
  • aminoaciduria
  • general physical health deterioration
  • cytomegalovirus infection
  • gastroduodenitis
  • maternal drugs affecting foetus
  • meningitis neonatal
2-9:
  • abdominal pain
  • depressed level of consciousness
  • cholecystitis acute
  • diarrhoea
  • somnolence
  • anaemia
  • electrocardiogram qt prolonged
  • graft versus host disease
  • hypotension
  • pancreatitis haemorrhagic
10-19:
  • vomiting
  • headache
  • abdominal pain
  • crohn's disease
  • nausea
  • pyrexia
  • intestinal stenosis
  • diarrhoea
  • ileus
  • loss of consciousness
20-29:
  • nausea
  • vomiting
  • abdominal pain upper
  • cholelithiasis
  • dyspepsia
  • cholecystitis chronic
  • abdominal pain
  • abdominal discomfort
  • injury
  • pain
30-39:
  • pruritus
  • pyrexia
  • constipation
  • fatigue
  • depression
  • nausea
  • abdominal pain
  • anaemia
  • arthralgia
  • pain in extremity
40-49:
  • pain
  • abdominal pain
  • back pain
  • anxiety
  • diarrhoea
  • osteonecrosis of jaw
  • oedema peripheral
  • pain in extremity
  • pyrexia
  • thrombocytopenia
50-59:
  • pain
  • anxiety
  • anaemia
  • osteonecrosis of jaw
  • spinal osteoarthritis
  • diarrhoea
  • bone disorder
  • gastrooesophageal reflux disease
  • oedema peripheral
  • pyrexia
60+:
  • pain
  • anxiety
  • vomiting
  • dyspnoea
  • diarrhoea
  • nausea
  • injury
  • bone disorder
  • osteonecrosis of jaw
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prilosec (omeprazole) is often used to treat gastrooesophageal reflux disease. Flagyl (metronidazole) is often used to treat crohn's disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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