Review: taking Prilosec and Flagyl together


Summary

Drug interactions are reported among people who take Prilosec and Flagyl together. This review analyzes the effectiveness and drug interactions between Prilosec and Flagyl. It is created by eHealthMe based on reports of 3,760 people who take the same drugs from FDA and social media, and is updated regularly.

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Prilosec

Prilosec has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Prilosec 79,264 users)

Flagyl

Flagyl has active ingredients of metronidazole. It is often used in crohn's disease. (latest outcomes from Flagyl 14,732 users)

On Sep, 16, 2016

3,760 people who take Prilosec, Flagyl are studied.


Number of reports submitted per year:

Prilosec and Flagyl drug interactions.

Drug effectiveness over time:

Prilosec:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 83.0% - (5 of 6 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 75.0% - (3 of 4 people)
  • 2 - 5 years: 100.0% - (5 of 5 people)
  • 5 - 10 years: 100.0% - (4 of 4 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Flagyl:
  • < 1 month: 43.0% - (7 of 16 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Prilosec:
  • female: 68.0% - (13 of 19 people)
  • male: 70.0% - (7 of 10 people)
Flagyl:
  • female: 37.0% - (6 of 16 people)
  • male: 54.0% - (6 of 11 people)

Drug effectiveness by age:

Prilosec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 28.0% - (2 of 7 people)
  • 40-49: 80.0% - (4 of 5 people)
  • 50-59: 60.0% - (3 of 5 people)
  • 60+: 87.0% - (7 of 8 people)
Flagyl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 57.0% - (4 of 7 people)
  • 40-49: 40.0% - (2 of 5 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 57.0% - (4 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • hypertension
  • pneumonia
  • convulsion
  • diarrhoea
  • clostridium difficile colitis
  • pulmonary oedema
  • pyrexia
  • international normalised ratio increased
  • thrombocytopenia
1 - 6 months:
  • anxiety
  • septic shock
  • pyrexia
  • hyperkalaemia
  • depression
  • emotional distress
  • gastrointestinal haemorrhage
  • general physical health deterioration
  • injury
  • suicidal ideation
6 - 12 months:
  • peripheral swelling
  • thrombocytopenia
  • meningitis neonatal
  • respiratory distress
  • aortic valve incompetence
  • atrial septal defect
  • cyanosis neonatal
  • meningitis aseptic
  • meningitis enteroviral
  • pulmonary valve stenosis
1 - 2 years:
  • blood glucose increased
  • insulin resistance
  • lightheadedness - fainting
  • abdominal pain
  • acne cystic
  • acne steroid-induced
  • allergic granulomatous angiitis
  • anxiety
  • aphagia
  • arthralgia
2 - 5 years:
  • pain
  • acute myeloid leukaemia
  • anxiety
  • emotional distress
  • anaemia
  • dyspepsia
  • general physical health deterioration
  • injury
  • abdominal pain upper
  • acute myocardial infarction
5 - 10 years:
  • arthritis
  • cramps - leg
  • cramps - muscle
  • diarrhoea
  • dizziness
  • fibromyalgia
  • gastrointestinal haemorrhage
  • ibs
  • joint stiffness
  • memory impairment
10+ years:
  • depression
  • anxiety
  • blood creatinine increased
  • intervertebral disc protrusion
  • neuropathy peripheral
  • osteoporosis
  • tarsal tunnel syndrome
  • acne
  • anaemia
  • arthritis
not specified:
  • pain
  • anxiety
  • diarrhoea
  • nausea
  • fatigue
  • dyspnoea
  • vomiting
  • anaemia
  • injury
  • pyrexia

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • diarrhoea
  • nausea
  • fatigue
  • injury
  • abdominal pain
  • dyspnoea
  • osteonecrosis of jaw
  • anaemia
male:
  • pain
  • vomiting
  • diarrhoea
  • anxiety
  • nausea
  • thrombocytopenia
  • pneumonia
  • anaemia
  • pyrexia
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • thrombocytopenia
  • disorientation
  • metabolic acidosis
  • myocardial infarction
  • meningitis neonatal
  • respiratory distress
  • aortic valve incompetence
  • atrial septal defect
  • cyanosis neonatal
  • meningitis aseptic
2-9:
  • abdominal pain
  • diarrhoea
  • cholecystitis acute
  • depressed level of consciousness
  • tracheitis
  • anaemia
  • cholelithiasis
  • somnolence
  • depression
  • electrocardiogram qt prolonged
10-19:
  • crohn's disease
  • headache
  • vomiting
  • abdominal pain
  • nausea
  • pain
  • pyrexia
  • diarrhoea
  • dehydration
  • intestinal stenosis
20-29:
  • nausea
  • vomiting
  • abdominal pain upper
  • pain
  • anxiety
  • dyspepsia
  • injury
  • cholelithiasis
  • cholecystitis chronic
  • abdominal pain
30-39:
  • pyrexia
  • fatigue
  • nausea
  • pulmonary embolism
  • arthralgia
  • constipation
  • abdominal pain
  • pruritus
  • depression
  • urinary tract infection
40-49:
  • pain
  • abdominal pain
  • back pain
  • anxiety
  • diarrhoea
  • pyrexia
  • osteonecrosis of jaw
  • oedema peripheral
  • pain in extremity
  • arthralgia
50-59:
  • pain
  • anxiety
  • anaemia
  • diarrhoea
  • pyrexia
  • nausea
  • gastrooesophageal reflux disease
  • fatigue
  • osteonecrosis of jaw
  • spinal osteoarthritis
60+:
  • pain
  • anxiety
  • diarrhoea
  • dyspnoea
  • vomiting
  • nausea
  • fatigue
  • injury
  • osteonecrosis of jaw
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prilosec (omeprazole) is often used to treat gastrooesophageal reflux disease. Flagyl (metronidazole) is often used to treat crohn's disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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