Review: taking Prilosec and Flagyl together


Summary

Drug interactions are reported among people who take Prilosec and Flagyl together. This review analyzes the effectiveness and drug interactions between Prilosec and Flagyl. It is created by eHealthMe based on reports of 2,960 people who take the same drugs from FDA and social media, and is updated regularly.

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Prilosec

Prilosec has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Prilosec 64,301 users)

Flagyl

Flagyl has active ingredients of metronidazole. It is often used in crohn's disease. (latest outcomes from Flagyl 11,791 users)

On Aug, 19, 2016

2,960 people who take Prilosec, Flagyl are studied.


Number of reports submitted per year:

Prilosec and Flagyl drug interactions.

Drug effectiveness over time:

Prilosec:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 83.0% - (5 of 6 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 75.0% - (3 of 4 people)
  • 2 - 5 years: 100.0% - (5 of 5 people)
  • 5 - 10 years: 100.0% - (4 of 4 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Flagyl:
  • < 1 month: 43.0% - (7 of 16 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Prilosec:
  • female: 68.0% - (13 of 19 people)
  • male: 70.0% - (7 of 10 people)
Flagyl:
  • female: 37.0% - (6 of 16 people)
  • male: 54.0% - (6 of 11 people)

Drug effectiveness by age:

Prilosec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 28.0% - (2 of 7 people)
  • 40-49: 80.0% - (4 of 5 people)
  • 50-59: 60.0% - (3 of 5 people)
  • 60+: 87.0% - (7 of 8 people)
Flagyl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 57.0% - (4 of 7 people)
  • 40-49: 40.0% - (2 of 5 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 57.0% - (4 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • hypertension
  • pneumonia
  • convulsion
  • pulmonary oedema
  • clostridium difficile colitis
  • diarrhoea
  • international normalised ratio increased
  • pyrexia
  • thrombocytopenia
1 - 6 months:
  • septic shock
  • hyperkalaemia
  • pyrexia
  • suicidal ideation
  • thrombocytopenia
  • depression
  • enterococcal infection
  • escherichia infection
  • gastrointestinal haemorrhage
  • haemoglobin decreased
6 - 12 months:
  • thrombocytopenia
  • meningitis neonatal
  • respiratory distress
  • aortic valve incompetence
  • atrial septal defect
  • cyanosis neonatal
  • meningitis aseptic
  • meningitis enteroviral
  • pulmonary valve stenosis
  • pneumonia bacterial
1 - 2 years:
  • blood glucose increased
  • insulin resistance
  • lightheadedness - fainting
  • abdominal pain
  • acne cystic
  • acne steroid-induced
  • aphagia
  • balance disorder
  • crohn's disease
  • depression aggravated
2 - 5 years:
  • pain
  • acute myeloid leukaemia
  • anxiety
  • emotional distress
  • anaemia
  • dyspepsia
  • general physical health deterioration
  • injury
  • abdominal pain upper
  • acute myocardial infarction
5 - 10 years:
  • arthritis
  • cramps - leg
  • cramps - muscle
  • diarrhoea
  • dizziness
  • fibromyalgia
  • ibs
  • joint stiffness
  • memory impairment
  • mobility decreased
10+ years:
  • depression
  • anxiety
  • blood creatinine increased
  • intervertebral disc protrusion
  • neuropathy peripheral
  • osteoporosis
  • tarsal tunnel syndrome
  • acne
  • anaemia
  • arthritis
not specified:
  • pain
  • anxiety
  • nausea
  • diarrhoea
  • dyspnoea
  • anaemia
  • osteonecrosis of jaw
  • injury
  • fatigue
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • diarrhoea
  • nausea
  • osteonecrosis of jaw
  • injury
  • dyspnoea
  • abdominal pain
  • fatigue
  • anaemia
male:
  • pain
  • vomiting
  • thrombocytopenia
  • anxiety
  • nausea
  • pneumonia
  • anaemia
  • pyrexia
  • hypotension
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • thrombocytopenia
  • disorientation
  • metabolic acidosis
  • myocardial infarction
  • meningitis neonatal
  • respiratory distress
  • aortic valve incompetence
  • atrial septal defect
  • cyanosis neonatal
  • meningitis aseptic
2-9:
  • abdominal pain
  • diarrhoea
  • cholecystitis acute
  • depressed level of consciousness
  • anaemia
  • cholelithiasis
  • somnolence
  • tracheitis
  • depression
  • electrocardiogram qt prolonged
10-19:
  • vomiting
  • headache
  • nausea
  • abdominal pain
  • crohn's disease
  • pyrexia
  • pain
  • diarrhoea
  • intestinal stenosis
  • hypertension
20-29:
  • nausea
  • abdominal pain upper
  • vomiting
  • cholelithiasis
  • dyspepsia
  • cholecystitis chronic
  • pain
  • abdominal pain
  • injury
  • diarrhoea
30-39:
  • pyrexia
  • pulmonary embolism
  • pruritus
  • constipation
  • fatigue
  • nausea
  • anaemia
  • depression
  • urinary tract infection
  • fall
40-49:
  • pain
  • abdominal pain
  • anxiety
  • back pain
  • pyrexia
  • diarrhoea
  • oedema peripheral
  • osteonecrosis of jaw
  • pain in extremity
  • arthralgia
50-59:
  • pain
  • anxiety
  • anaemia
  • diarrhoea
  • osteonecrosis of jaw
  • gastrooesophageal reflux disease
  • pyrexia
  • spinal osteoarthritis
  • bone disorder
  • oedema peripheral
60+:
  • pain
  • anxiety
  • vomiting
  • dyspnoea
  • diarrhoea
  • nausea
  • injury
  • fatigue
  • osteonecrosis of jaw
  • bone disorder

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prilosec (omeprazole) is often used to treat gastrooesophageal reflux disease. Flagyl (metronidazole) is often used to treat crohn's disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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