Review: taking Prograf and Doxycycline together


Summary

Drug interactions are reported among people who take Prograf and Doxycycline together. This review analyzes the effectiveness and drug interactions between Prograf and Doxycycline. It is created by eHealthMe based on reports of 125 people who take the same drugs from FDA and social media, and is updated regularly.

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Prograf

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. (latest outcomes from Prograf 23,074 users)

Doxycycline

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. (latest outcomes from Doxycycline 15,796 users)

On Aug, 22, 2016

125 people who take Prograf, Doxycycline are studied.


Number of reports submitted per year:

Prograf and Doxycycline drug interactions.

Most common drug interactions over time *:

< 1 month:
  • abscess
  • blood creatinine increased
  • exostosis
  • international normalised ratio increased
  • localised infection
  • muscular weakness
  • post procedural haemorrhage
  • skin ulcer
  • engraft failure
  • pulmonary haemorrhage
1 - 6 months:
  • engraft failure
  • pulmonary haemorrhage
  • stenotrophomonas infection
  • chronic graft versus host disease
  • gastrointestinal haemorrhage
  • hyperkalaemia
  • hypertension
  • infection
  • insomnia
  • malabsorption
6 - 12 months:
  • osteopenia
  • ovarian cyst
  • acne
  • alopecia
  • conjunctivitis
  • erythema of eyelid
  • anaemia
  • biopsy breast abnormal
  • breast cancer female
  • intervertebral disc protrusion
1 - 2 years:
  • postoperative ileus
  • renal failure acute
  • device related infection
2 - 5 years:
  • cardiac arrest
  • confusional state
  • memory impairment
not specified:
  • hypoaesthesia
  • dyspnoea
  • anaemia
  • intervertebral disc protrusion
  • osteoarthritis
  • back pain
  • abscess
  • chest pain
  • flank pain
  • impaired healing

Most common drug interactions by gender *:

female:
  • pain
  • alopecia
  • intervertebral disc protrusion
  • anaemia
  • neck pain
  • biopsy breast abnormal
  • breast cancer female
  • osteoarthritis
  • osteopenia
  • ovarian cyst
male:
  • abscess
  • hypoaesthesia
  • dyspnoea
  • anaemia
  • aortic aneurysm
  • flank pain
  • gingival disorder
  • impaired healing
  • open wound
  • osteomyelitis

Most common drug interactions by age *:

10-19:
  • drug ineffective
  • psoriasis
  • therapeutic response unexpected
20-29:
  • amnesia
  • chest pain
  • corneal abrasion
  • disturbance in attention
  • dyspnoea
  • foreign body in eye
  • hodgkin's disease
  • hypoaesthesia
  • joint dislocation
  • lymphadenopathy
30-39:
  • anaemia
  • biopsy breast abnormal
  • breast cancer female
  • intervertebral disc protrusion
  • osteopenia
  • ovarian cyst
  • acne
  • alopecia
  • conjunctivitis
  • erythema of eyelid
40-49:
  • abscess
  • blood creatinine increased
  • muscular weakness
  • skin ulcer
  • exostosis
  • international normalised ratio increased
  • localised infection
  • post procedural haemorrhage
  • hypoaesthesia
  • cardiac arrest
50-59:
  • engraft failure
  • pulmonary haemorrhage
  • stenotrophomonas infection
  • nephropathy toxic
  • aspergillosis
  • bone marrow failure
  • hypoaesthesia
  • muscular weakness
  • rhodococcus infection
  • skin cancer
60+:
  • back pain
  • anaemia
  • aortic aneurysm
  • flank pain
  • gingival disorder
  • impaired healing
  • mitral valve incompetence
  • open wound
  • osteomyelitis
  • osteonecrosis of jaw

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prograf (tacrolimus) is often used to treat kidney transplant. Doxycycline (doxycycline hyclate) is often used to treat acne. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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