Review: taking Promethazine and Buspirone hydrochloride together


Summary

Drug interactions are reported among people who take Promethazine and Buspirone hydrochloride together. This review analyzes the effectiveness and drug interactions between Promethazine and Buspirone hydrochloride. It is created by eHealthMe based on reports of 440 people who take the same drugs from FDA and social media, and is updated regularly.

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Promethazine

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from Promethazine 7,296 users)

Buspirone Hydrochloride

Buspirone hydrochloride has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. (latest outcomes from Buspirone hydrochloride 1,285 users)

On Sep, 19, 2016

440 people who take Promethazine, Buspirone Hydrochloride are studied.


Number of reports submitted per year:

Promethazine and Buspirone hydrochloride drug interactions.

Drug effectiveness over time:

Promethazine:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 100.0% - (2 of 2 people)
Buspirone Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Promethazine:
  • female: 55.0% - (5 of 9 people)
  • male: 100.0% - (1 of 1 people)
Buspirone Hydrochloride:
  • female: 33.0% - (3 of 9 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Promethazine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 60.0% - (3 of 5 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Buspirone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 20.0% - (1 of 5 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • acute respiratory distress syndrome
  • anoxia
  • cardio-respiratory arrest
  • cellulitis
  • colonic perforation
  • coma
  • faeces hard
  • hypoxic encephalopathy
  • leukocytosis
1 - 6 months:
  • amenorrhea - secondary
  • nausea
  • cough
  • pneumonia
  • pruritus
  • serotonin syndrome
  • sinusitis
  • throat irritation
6 - 12 months:
  • abdominal pain
  • biliary dyskinesia
  • cholecystitis chronic
  • diarrhoea
  • nausea
  • retching
  • vomiting
  • allergic respiratory disease
  • bradycardia neonatal
  • breech presentation
1 - 2 years:
  • acid reflux
  • anxiety
  • chronic depression
  • basedow's disease
  • diabetic foot
  • diabetic neuropathy
  • gallbladder operation
  • gastrointestinal haemorrhage
  • obesity
  • pancreatic disorder
2 - 5 years:
  • acid reflux
  • anxiety
  • chronic depression
  • weight decreased
  • abdominal distension
  • abdominal neoplasm
  • abdominal pain aggravated
  • anemia - b12 deficiency
  • anemia - hemolytic
  • bile duct pressure increased
10+ years:
  • sinusitis
  • abdominal distension
  • abdominal neoplasm
  • abdominal pain aggravated
  • ammonia increased
  • anemia - b12 deficiency
  • anemia - hemolytic
  • bile duct pressure increased
  • bone and joint pain
  • cough
not specified:
  • anxiety
  • nausea
  • depression
  • pain
  • dyspnoea
  • fall
  • abdominal pain
  • oedema peripheral
  • headache
  • diarrhoea

Most common drug interactions by gender *:

female:
  • anxiety
  • nausea
  • depression
  • pain
  • fall
  • oedema peripheral
  • headache
  • abdominal pain
  • gastrooesophageal reflux disease
  • pain in extremity
male:
  • dyspnoea
  • anxiety
  • diarrhoea
  • nausea
  • vomiting
  • injury
  • pain
  • chest pain
  • abdominal pain
  • dizziness

Most common drug interactions by age *:

0-1:
  • caudal regression syndrome
  • congenital eye disorder
  • foetal exposure during pregnancy
  • talipes
10-19:
  • anxiety
  • biliary colic
  • depression
  • diarrhoea
  • migraine
  • nausea
  • abdominal pain upper
  • cholecystitis chronic
  • gallbladder cholesterolosis
  • diabetes mellitus
20-29:
  • nausea
  • cholecystitis chronic
  • vomiting
  • biliary dyskinesia
  • diarrhoea
  • retching
  • abdominal pain
  • abdominal pain upper
  • anhedonia
  • cervical adenitis
30-39:
  • nausea
  • anxiety
  • fall
  • malaise
  • cellulitis
  • diabetes mellitus
  • dyspepsia
  • vomiting
  • pain
  • cholecystitis chronic
40-49:
  • anxiety
  • oedema peripheral
  • constipation
  • depression
  • general physical health deterioration
  • bone pain
  • decreased interest
  • dyspnoea
  • upper respiratory tract infection
  • arthralgia
50-59:
  • pneumonia
  • type 2 diabetes mellitus
  • dizziness
  • drug ineffective
  • pain
  • weight increased
  • anaemia
  • dyspnoea
  • gastrooesophageal reflux disease
  • neuropathy peripheral
60+:
  • anxiety
  • depression
  • fall
  • dyspnoea
  • mental status changes
  • vomiting
  • gastrooesophageal reflux disease
  • pneumonia
  • anaemia
  • urinary tract infection

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Promethazine (promethazine hydrochloride) is often used to treat nausea. Buspirone hydrochloride (buspirone hydrochloride) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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