Review: taking Promethazine and Cyclobenzaprine hydrochloride together


Summary

Drug interactions are reported among people who take Promethazine and Cyclobenzaprine hydrochloride together. This review analyzes the effectiveness and drug interactions between Promethazine and Cyclobenzaprine hydrochloride. It is created by eHealthMe based on reports of 822 people who take the same drugs from FDA and social media, and is updated regularly.

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Promethazine

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from Promethazine 245 users)

Cyclobenzaprine Hydrochloride

Cyclobenzaprine hydrochloride has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Cyclobenzaprine hydrochloride 2,289 users)

On Jul, 30, 2016

822 people who take Promethazine, Cyclobenzaprine Hydrochloride are studied.


Number of reports submitted per year:

Promethazine and Cyclobenzaprine hydrochloride drug interactions.

Drug effectiveness over time:

Promethazine:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 42.0% - (3 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 71.0% - (5 of 7 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 100.0% - (1 of 1 people)
Cyclobenzaprine Hydrochloride:
  • < 1 month: 50.0% - (3 of 6 people)
  • 1 - 6 months: 16.0% - (1 of 6 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 4 people)
  • 5 - 10 years: 60.0% - (3 of 5 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Promethazine:
  • female: 45.0% - (10 of 22 people)
  • male: 75.0% - (3 of 4 people)
Cyclobenzaprine Hydrochloride:
  • female: 26.0% - (6 of 23 people)
  • male: 75.0% - (3 of 4 people)

Drug effectiveness by age:

Promethazine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 42.0% - (3 of 7 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 0.0% - (0 of 0 people)
Cyclobenzaprine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 44.0% - (4 of 9 people)
  • 50-59: 14.0% - (1 of 7 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • constipation
  • death
  • nausea
  • pulmonary embolism
  • suicide attempt
  • cardiac arrest
  • cholecystitis chronic
  • depression
  • vomiting
1 - 6 months:
  • anxiety
  • blood pressure increased
  • breath holding
  • burning mouth syndrome
  • heartburn - chronic
  • hormone level abnormal
  • low thyroid
  • migraine
  • nausea
  • pain
6 - 12 months:
  • anxiety
  • blood pressure increased
  • heartburn - chronic
  • hormone level abnormal
  • low thyroid
  • migraine
  • nausea
  • pain exacerbated
  • abdominal wall haematoma
  • acne
1 - 2 years:
  • breast tenderness
  • drowsiness
  • fatigue
  • flatulence
  • short-term memory loss
  • sinus tachycardia
2 - 5 years:
  • pain
  • pancreatitis chronic
  • back pain
  • pyrexia
  • abdominal pain lower
  • abdominal pain upper
  • biliary colic
  • drowsiness
  • gallbladder disorder
  • nausea
5 - 10 years:
  • erection problems
  • skin striae
not specified:
  • pain
  • back pain
  • anxiety
  • nausea
  • headache
  • osteonecrosis of jaw
  • pain in extremity
  • osteoarthritis
  • chest pain
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • back pain
  • anxiety
  • nausea
  • headache
  • chest pain
  • pain in extremity
  • osteonecrosis of jaw
  • fall
  • dyspnoea
male:
  • pain
  • anxiety
  • nausea
  • osteoporosis
  • asthenia
  • pyrexia
  • osteoarthritis
  • cellulitis
  • constipation
  • hypotension

Most common drug interactions by age *:

10-19:
  • cholecystitis
  • nausea
  • abdominal pain
  • abdominal pain upper
  • cholelithiasis
  • colitis
  • decreased appetite
  • diarrhoea
  • dyspepsia
  • gallbladder disorder
20-29:
  • nausea
  • back pain
  • cholecystitis chronic
  • abdominal pain upper
  • pulmonary embolism
  • gallbladder disorder
  • pain
  • headache
  • vomiting
  • chest pain
30-39:
  • nausea
  • type 2 diabetes mellitus
  • vomiting
  • anxiety
  • constipation
  • diabetes mellitus
  • pain
  • back pain
  • deep vein thrombosis
  • emotional distress
40-49:
  • pain
  • depression
  • pain in extremity
  • nausea
  • abdominal pain
  • chest pain
  • anxiety
  • arthralgia
  • osteonecrosis of jaw
  • back pain
50-59:
  • pain
  • anxiety
  • back pain
  • diarrhoea
  • osteoarthritis
  • sinusitis
  • headache
  • hypoaesthesia
  • anaemia
  • dehydration
60+:
  • osteomyelitis
  • back pain
  • osteoarthritis
  • osteonecrosis of jaw
  • anxiety
  • weight decreased
  • fall
  • anaemia
  • pain
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Promethazine (promethazine hydrochloride) is often used to treat nausea. Cyclobenzaprine hydrochloride (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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