Review: taking Propranolol hydrochloride and Zanaflex together


Summary

Drug interactions are reported among people who take Propranolol hydrochloride and Zanaflex together. This review analyzes the effectiveness and drug interactions between Propranolol hydrochloride and Zanaflex. It is created by eHealthMe based on reports of 407 people who take the same drugs from FDA and social media, and is updated regularly.

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Propranolol Hydrochloride

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in migraine. (latest outcomes from Propranolol hydrochloride 4,019 users)

Zanaflex

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 10,094 users)

On Sep, 20, 2016

407 people who take Propranolol Hydrochloride, Zanaflex are studied.


Number of reports submitted per year:

Propranolol hydrochloride and Zanaflex drug interactions.

Drug effectiveness over time:

Propranolol Hydrochloride:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 57.0% - (4 of 7 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)
Zanaflex:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 50.0% - (3 of 6 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Propranolol Hydrochloride:
  • female: 40.0% - (6 of 15 people)
  • male: 75.0% - (3 of 4 people)
Zanaflex:
  • female: 35.0% - (6 of 17 people)
  • male: 40.0% - (2 of 5 people)

Drug effectiveness by age:

Propranolol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (3 of 3 people)
  • 30-39: 40.0% - (2 of 5 people)
  • 40-49: 33.0% - (2 of 6 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 2 people)
Zanaflex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 75.0% - (3 of 4 people)
  • 30-39: 0.0% - (0 of 5 people)
  • 40-49: 42.0% - (3 of 7 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • blood creatinine increased
  • blood pressure increased
  • bradycardia
  • drug administration error
  • dysphagia
  • electrocardiogram qt prolonged
  • general physical health deterioration
  • loss of consciousness
  • muscle spasms
1 - 6 months:
  • injury
  • night sweats
  • abdominal bloating
  • abdominal pain
  • anhedonia
  • anxiety
  • chest tightness
  • chills
  • cough
  • depression
6 - 12 months:
  • vertigo
  • acid reflux
  • allergy to animal
  • allergy to chemicals
  • allergy to plants
  • anxiety
  • back pain - low
  • eczema
  • genital pain
  • high blood pressure
1 - 2 years:
  • vertigo
  • acid reflux
  • allergy to animal
  • allergy to chemicals
  • allergy to plants
  • anxiety
  • back pain - low
  • eczema
  • genital pain
  • high blood pressure
2 - 5 years:
  • fatigue - chronic
  • fever
  • insomnia
  • migraine
  • abdominal bloating
  • abdominal pain
  • chest tightness
  • chills
  • cough
  • diarrhoea post-operative
10+ years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • rapid deep breathing (hyperventilation)
  • weight gain - unintentional
not specified:
  • pain
  • depression
  • nausea
  • headache
  • anxiety
  • hypertension
  • insomnia
  • arthralgia
  • dyspnoea
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • depression
  • nausea
  • anxiety
  • dyspnoea
  • insomnia
  • fatigue
  • migraine
  • headache
  • arthralgia
male:
  • headache
  • pain
  • hypertension
  • nausea
  • depression
  • anxiety
  • brain injury
  • constipation
  • renal failure acute
  • drug withdrawal syndrome

Most common drug interactions by age *:

10-19:
  • hypotension
  • fatigue
  • arthralgia
  • bradycardia
  • difficulty in walking
  • drug administration error
  • general physical health deterioration
  • overdose
  • peripheral swelling
  • urinary tract infection
20-29:
  • fatigue
  • pyrexia
  • tremor
  • weight increased
  • blood potassium decreased
  • chest pain
  • convulsion
  • dysarthria
  • heart rate irregular
  • hypertension
30-39:
  • pain
  • agitation
  • headache
  • dyspnoea
  • anxiety
  • arthralgia
  • vision blurred
  • migraine
  • nausea
  • hypertension
40-49:
  • depression
  • pain
  • nausea
  • headache
  • insomnia
  • arthralgia
  • hypertension
  • vomiting
  • abdominal pain
  • dizziness
50-59:
  • fall
  • insomnia
  • depression
  • dehydration
  • pain
  • renal failure acute
  • drug ineffective
  • hypertension
  • mental status changes
  • blood sodium decreased
60+:
  • anxiety
  • pain
  • accident
  • amnesia
  • anhedonia
  • brain injury
  • deep vein thrombosis
  • emotional distress
  • fear
  • general physical health deterioration

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Propranolol hydrochloride (propranolol hydrochloride) is often used to treat migraine. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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