Review: taking Provigil and Nuvigil together


Summary

Drug interactions are reported among people who take Provigil and Nuvigil together. This review analyzes the effectiveness and drug interactions between Provigil and Nuvigil. It is created by eHealthMe based on reports of 176 people who take the same drugs from FDA and social media, and is updated regularly.

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Provigil

Provigil has active ingredients of modafinil. It is often used in fatigue. (latest outcomes from Provigil 10,174 users)

Nuvigil

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. (latest outcomes from Nuvigil 4,305 users)

On Jul, 17, 2016

176 people who take Provigil, Nuvigil are studied.


Number of reports submitted per year:

Provigil and Nuvigil drug interactions.

Drug effectiveness over time:

Provigil:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 3 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Nuvigil:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Provigil:
  • female: 25.0% - (1 of 4 people)
  • male: 0.0% - (0 of 0 people)
Nuvigil:
  • female: 50.0% - (2 of 4 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Provigil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Nuvigil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • anxiety
  • dysarthria
  • dysphonia
  • headache
  • paraesthesia oral
  • speech disorder
  • transient ischaemic attack
  • affect lability
  • amnesia
1 - 6 months:
  • anger
  • drug ineffective
  • decreased appetite
  • depression
  • headache
  • nausea
  • pain in extremity
  • acne aggravated
  • constipation
  • loss of appetite
6 - 12 months:
  • nausea
  • headache
  • anger
  • decreased appetite
  • depression
  • drug ineffective
  • irritability
  • pain in extremity
  • abdominal distension
  • amnesia
1 - 2 years:
  • anger
  • decreased appetite
  • depression
  • drug ineffective
  • headache
  • nausea
  • pain in extremity
  • rash generalised
  • aggression
  • alopecia
2 - 5 years:
  • aphthous stomatitis
  • cheilitis
  • dysarthria
  • dysphonia
  • lip swelling
  • speech disorder
  • swollen tongue
  • therapeutic response unexpected
  • urinary incontinence
5 - 10 years:
  • cardiovascular disorder
  • death
  • deep vein thrombosis
  • pulmonary embolism
  • chest pain
  • drug ineffective
  • dyspnoea
  • oesophageal spasm
  • oropharyngeal pain
  • tremor
not specified:
  • drug ineffective
  • headache
  • nausea
  • dizziness
  • rash
  • abdominal pain upper
  • anxiety
  • fatigue
  • migraine
  • upper respiratory tract infection

Most common drug interactions by gender *:

female:
  • headache
  • nausea
  • dizziness
  • abdominal pain upper
  • bronchitis
  • drug ineffective
  • urinary tract infection
  • deep vein thrombosis
  • convulsion
  • migraine
male:
  • drug ineffective
  • depression
  • headache
  • nausea
  • death
  • decreased appetite
  • anxiety
  • euphoric mood
  • anger
  • pain in extremity

Most common drug interactions by age *:

10-19:
  • anger
  • decreased appetite
  • depression
  • drug ineffective
  • headache
  • nausea
  • pain in extremity
  • rhabdomyolysis
20-29:
  • deep vein thrombosis
  • pulmonary embolism
  • abdominal pain upper
  • back pain
  • chest pain
  • dental caries
  • drug ineffective
  • dyspnoea
  • fatigue
  • musculoskeletal stiffness
30-39:
  • convulsion
  • headache
  • deep vein thrombosis
  • dysarthria
  • nausea
  • confusional state
  • decreased appetite
  • panic reaction
  • gait disturbance
  • insomnia
40-49:
  • flushing
  • back pain
  • headache
  • memory impairment
  • nausea
  • pyrexia
  • abdominal distension
  • disorientation
  • dizziness
  • dyspnoea
50-59:
  • upper respiratory tract infection
  • nausea
  • bronchitis
  • cough
  • general physical health deterioration
  • sinusitis
  • urinary tract infection
  • death
  • dizziness
  • facial pain
60+:
  • rash
  • drug ineffective
  • dizziness
  • gastrooesophageal reflux disease
  • somnolence
  • activities of daily living impaired
  • alanine aminotransferase increased
  • aortic arteriosclerosis
  • arthralgia
  • aspartate aminotransferase increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Provigil (modafinil) is often used to treat fatigue. Nuvigil (armodafinil) is often used to treat narcolepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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