Review: taking Provigil and Propranolol hydrochloride together


Summary

Drug interactions are reported among people who take Provigil and Propranolol hydrochloride together. This review analyzes the effectiveness and drug interactions between Provigil and Propranolol hydrochloride. It is created by eHealthMe based on reports of 254 people who take the same drugs from FDA and social media, and is updated regularly.

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Provigil

Provigil has active ingredients of modafinil. It is often used in fatigue. (latest outcomes from Provigil 11,084 users)

Propranolol Hydrochloride

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in migraine. (latest outcomes from Propranolol hydrochloride 3,525 users)

On Aug, 23, 2016

254 people who take Provigil, Propranolol Hydrochloride are studied.


Number of reports submitted per year:

Provigil and Propranolol hydrochloride drug interactions.

Drug effectiveness over time:

Provigil:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 50.0% - (4 of 8 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (3 of 3 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Propranolol Hydrochloride:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 42.0% - (3 of 7 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 80.0% - (4 of 5 people)
  • 2 - 5 years: 100.0% - (3 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Provigil:
  • female: 37.0% - (6 of 16 people)
  • male: 66.0% - (6 of 9 people)
Propranolol Hydrochloride:
  • female: 56.0% - (9 of 16 people)
  • male: 60.0% - (6 of 10 people)

Drug effectiveness by age:

Provigil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (6 of 12 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 50.0% - (1 of 2 people)
Propranolol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 58.0% - (7 of 12 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • syncope
  • bradycardia
  • diarrhoea
  • feeling jittery
  • toxic epidermal necrolysis
  • abdominal pain
  • balance disorder
  • beta haemolytic streptococcal infection
  • candidiasis
  • culture throat positive
1 - 6 months:
  • weight gain
  • frequent headaches
  • agitation
  • anxiety
  • confusion
  • depression
  • drowsiness
  • drug addiction
  • forgetfulness
  • impaired memory
6 - 12 months:
  • agitation
  • anxiety
  • confusion
  • depression
  • drowsiness
  • drug addiction
  • forgetfulness
  • impaired memory
  • loss of appetite
  • memory impairment
1 - 2 years:
  • tinnitus
  • altered visual depth perception
  • aphasia
  • numbness and tingling
  • vertigo
  • diarrhoea
  • edema
  • back pain
  • eye swelling
  • hypersomnia
2 - 5 years:
  • blepharospasm
  • chest pain
  • cushing's syndrome
  • deep vein thrombosis
  • injury
  • lipids
  • metabolic syndrome
  • muscle spasms
  • neuroma
  • oedema peripheral
5 - 10 years:
  • drug exposure during pregnancy
  • dizziness
  • dry eyes
  • mouth ulcers
  • edema
  • abortion spontaneous
10+ years:
  • altered visual depth perception
  • aphasia
  • numbness and tingling
  • tinnitus
  • vertigo
  • dizziness
  • urinary retention
  • vasomotor rhinitis
not specified:
  • convulsion
  • fibromyalgia
  • fall
  • nausea
  • anxiety
  • dyspnoea
  • pain
  • weight increased
  • hypotension
  • vomiting

Most common drug interactions by gender *:

female:
  • convulsion
  • fibromyalgia
  • fall
  • anxiety
  • dyspnoea
  • nausea
  • pain
  • weight increased
  • depression
  • hypotension
male:
  • completed suicide
  • death
  • cardio-respiratory arrest
  • cardiac arrest
  • blood cholesterol increased
  • nausea
  • respiratory arrest
  • anal cancer metastatic
  • cerebrovascular accident
  • confusional state

Most common drug interactions by age *:

10-19:
  • difficulty in walking
  • dizziness
  • dyspnoea
  • dysstasia
  • headache
  • heart rate increased
  • lethargy
  • muscular dystrophy
  • narcolepsy
  • pallor
20-29:
  • anaphylactic reaction
  • feeling jittery
  • nausea
  • syncope
  • abasia
  • anaemia
  • asthma
  • brain death
  • brain herniation
  • coeliac disease
30-39:
  • anxiety
  • dyspnoea
  • edema
  • hyperhidrosis
  • initial insomnia
  • multiple sclerosis relapse
  • nausea
  • pulmonary embolism
  • vomiting
  • weight gain
40-49:
  • convulsion
  • fibromyalgia
  • fall
  • oedema peripheral
  • drug ineffective
  • fatigue
  • hypothyroidic goitre
  • ovarian epithelial cancer
  • thyroidectomy
  • accidental overdose
50-59:
  • fall
  • anxiety
  • hypotension
  • weight increased
  • death
  • dysphagia
  • nausea
  • dehydration
  • diarrhoea
  • dyspnoea
60+:
  • completed suicide
  • cardio-respiratory arrest
  • cardiac arrest
  • pain
  • affective disorder
  • anxiety
  • nausea
  • red blood cell sedimentation rate increased
  • respiratory arrest
  • visual impairment

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Provigil (modafinil) is often used to treat fatigue. Propranolol hydrochloride (propranolol hydrochloride) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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