Review: taking Prozac and Xanax together


Summary

Drug interactions are reported among people who take Prozac and Xanax together. This review analyzes the effectiveness and drug interactions between Prozac and Xanax. It is created by eHealthMe based on reports of 7,666 people who take the same drugs from FDA and social media, and is updated regularly.

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Prozac

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Prozac 55,554 users)

Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 82,506 users)

On Sep, 13, 2016

7,666 people who take Prozac, Xanax are studied.


Number of reports submitted per year:

Prozac and Xanax drug interactions.

Drug effectiveness over time:

Prozac:
  • < 1 month: 9.0% - (3 of 33 people)
  • 1 - 6 months: 21.0% - (12 of 56 people)
  • 6 - 12 months: 15.0% - (6 of 38 people)
  • 1 - 2 years: 27.0% - (13 of 47 people)
  • 2 - 5 years: 40.0% - (17 of 42 people)
  • 5 - 10 years: 54.0% - (19 of 35 people)
  • 10+ years: 46.0% - (21 of 45 people)
  • not specified: 0.0% - (0 of 0 people)
Xanax:
  • < 1 month: 40.0% - (15 of 37 people)
  • 1 - 6 months: 44.0% - (28 of 63 people)
  • 6 - 12 months: 44.0% - (17 of 38 people)
  • 1 - 2 years: 50.0% - (24 of 48 people)
  • 2 - 5 years: 57.0% - (26 of 45 people)
  • 5 - 10 years: 70.0% - (24 of 34 people)
  • 10+ years: 73.0% - (25 of 34 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Prozac:
  • female: 32.0% - (80 of 244 people)
  • male: 21.0% - (11 of 52 people)
Xanax:
  • female: 52.0% - (131 of 249 people)
  • male: 57.0% - (30 of 52 people)

Drug effectiveness by age:

Prozac:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 45.0% - (5 of 11 people)
  • 20-29: 33.0% - (17 of 51 people)
  • 30-39: 26.0% - (21 of 79 people)
  • 40-49: 23.0% - (17 of 71 people)
  • 50-59: 35.0% - (20 of 56 people)
  • 60+: 40.0% - (11 of 27 people)
Xanax:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 55.0% - (5 of 9 people)
  • 20-29: 61.0% - (34 of 55 people)
  • 30-39: 56.0% - (45 of 80 people)
  • 40-49: 42.0% - (30 of 71 people)
  • 50-59: 50.0% - (28 of 55 people)
  • 60+: 60.0% - (18 of 30 people)

Most common drug interactions over time *:

< 1 month:
  • drug abuse
  • sopor
  • suicide attempt
  • intentional overdose
  • hypotension
  • completed suicide
  • overdose
  • anxiety
  • coma
  • loss of consciousness
1 - 6 months:
  • anxiety
  • nausea
  • vomiting
  • asthenia
  • insomnia
  • type 2 diabetes mellitus
  • back pain
  • obesity
  • fatigue
  • hyperglycaemia
6 - 12 months:
  • anxiety
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • depression
  • fibromyalgia syndrome
  • back pain
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue
  • pulmonary embolism
1 - 2 years:
  • anxiety
  • back pain
  • depression
  • pain
  • weight increased
  • dizziness
  • insomnia
  • nausea
  • hypertension
  • arthralgia
2 - 5 years:
  • anxiety
  • depression
  • pain
  • emotional distress
  • gallbladder disorder
  • myocardial infarction
  • nausea
  • type 2 diabetes mellitus
  • cholecystitis chronic
  • coronary artery disease
5 - 10 years:
  • depression
  • anxiety
  • pain
  • emotional distress
  • suicide attempt
  • headache
  • influenza
  • insomnia
  • diabetes mellitus inadequate control
  • injury
10+ years:
  • anxiety
  • drug ineffective
  • insomnia
  • depression
  • feeling abnormal
  • palpitations
  • back pain
  • diabetes mellitus
  • dizziness
  • fall
not specified:
  • depression
  • anxiety
  • nausea
  • pain
  • fatigue
  • drug ineffective
  • dyspnoea
  • headache
  • arthralgia
  • fall

Most common drug interactions by gender *:

female:
  • depression
  • pain
  • nausea
  • anxiety
  • fatigue
  • dyspnoea
  • fall
  • headache
  • arthralgia
  • dizziness
male:
  • anxiety
  • depression
  • fatigue
  • drug ineffective
  • nausea
  • asthenia
  • pain
  • suicidal ideation
  • insomnia
  • headache

Most common drug interactions by age *:

0-1:
  • premature baby
  • maternal drugs affecting foetus
  • foetal exposure during pregnancy
  • drug exposure during pregnancy
  • neonatal disorder
  • bradycardia neonatal
  • cardiac arrest
  • drug withdrawal syndrome neonatal
  • respiratory arrest
  • cyanosis neonatal
2-9:
  • fallot's tetralogy
  • foetal exposure during pregnancy
  • respiratory tract infection
  • sturge-weber syndrome
  • therapeutic response delayed
  • brain damage
  • coma
  • haemangioma congenital
  • hepatic failure
  • overdose
10-19:
  • depression
  • suicidal ideation
  • electrocardiogram qt prolonged
  • weight increased
  • musculoskeletal stiffness
  • blood prolactin increased
  • completed suicide
  • anxiety
  • lethargy
  • galactorrhoea
20-29:
  • anxiety
  • depression
  • insomnia
  • suicidal ideation
  • drug ineffective
  • pain
  • fatigue
  • back pain
  • suicide attempt
  • nausea
30-39:
  • anxiety
  • depression
  • weight increased
  • nausea
  • pain
  • drug abuse
  • fatigue
  • insomnia
  • asthenia
  • dyspnoea
40-49:
  • depression
  • pain
  • nausea
  • fatigue
  • anxiety
  • headache
  • chest pain
  • dyspnoea
  • arthralgia
  • back pain
50-59:
  • anxiety
  • depression
  • fatigue
  • nausea
  • pain
  • arthralgia
  • pain in extremity
  • fall
  • headache
  • back pain
60+:
  • nausea
  • fall
  • pain
  • fatigue
  • anxiety
  • dyspnoea
  • diarrhoea
  • depression
  • headache
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Prozac (fluoxetine hydrochloride) is often used to treat depression. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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