Review: taking Restoril and Plaquenil together


Summary

Drug interactions are reported among people who take Restoril and Plaquenil together. This review analyzes the effectiveness and drug interactions between Restoril and Plaquenil. It is created by eHealthMe based on reports of 334 people who take the same drugs from FDA and social media, and is updated regularly.

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Restoril

Restoril has active ingredients of temazepam. It is often used in insomnia. (latest outcomes from Restoril 8,253 users)

Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. (latest outcomes from Plaquenil 19,931 users)

On Aug, 27, 2016

334 people who take Restoril, Plaquenil are studied.


Number of reports submitted per year:

Restoril and Plaquenil drug interactions.

Drug effectiveness over time:

Restoril:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Plaquenil:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 25.0% - (1 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Restoril:
  • female: 66.0% - (4 of 6 people)
  • male: 0.0% - (0 of 1 people)
Plaquenil:
  • female: 33.0% - (2 of 6 people)
  • male: 100.0% - (1 of 1 people)

Drug effectiveness by age:

Restoril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 50.0% - (3 of 6 people)
  • 60+: 0.0% - (0 of 0 people)
Plaquenil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (3 of 6 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

6 - 12 months:
  • systemic lupus erythematosus
  • type 2 diabetes mellitus
  • headache - mixed tension migraine
1 - 2 years:
  • depression
  • headache - mixed tension migraine
  • ptsd
2 - 5 years:
  • depression
  • cognitive deterioration
  • dizziness
  • fatigue - chronic
  • gait abnormal
  • hyperacusis
  • hyporeflexia
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle twitching
  • myelomalacia
10+ years:
  • acidosis
  • bradycardia
  • cardiac arrest
  • cardiac disorder
  • cardiac failure
  • cardiomyopathy
  • coagulopathy
  • hepatic enzyme increased
  • hepatic failure
  • iatrogenic injury
not specified:
  • nausea
  • asthenia
  • arthralgia
  • fall
  • headache
  • anxiety
  • fatigue
  • pain
  • confusional state
  • erythema

Most common drug interactions by gender *:

female:
  • nausea
  • arthralgia
  • fall
  • fatigue
  • headache
  • anxiety
  • erythema
  • myocardial infarction
  • hip fracture
  • depression
male:
  • multi-organ failure
  • progressive multifocal leukoencephalopathy
  • asthenia
  • hemiparesis
  • respiratory failure
  • cerebrovascular accident
  • confusional state
  • aphasia
  • dysarthria
  • nervous system disorder

Most common drug interactions by age *:

10-19:
  • coma
20-29:
  • arthralgia
  • diarrhoea
  • dizziness
  • dysphagia
  • dyspnoea
  • fatigue
  • nausea
  • pain
  • pyrexia
  • rash
30-39:
  • electrocardiogram qt prolonged
  • dizziness
  • palpitations
  • tachycardia
  • arthritis
  • lung abscess
  • pneumonia
  • sepsis
  • sjogren's syndrome
  • weight decreased
40-49:
  • myalgia
  • pain
  • cardiac arrest
  • pyrexia
  • electrocardiogram qt prolonged
  • fatigue
  • torsade de pointes
  • nausea
  • arthralgia
  • cardiac failure
50-59:
  • nausea
  • fatigue
  • headache
  • arthralgia
  • fall
  • rheumatoid arthritis
  • osteoarthritis
  • tremor
  • anaemia
  • urinary tract infection
60+:
  • anxiety
  • asthenia
  • confusional state
  • cataract
  • arthropathy
  • nervousness
  • depression
  • gastrointestinal disorder
  • cough
  • heart rate irregular

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Restoril (temazepam) is often used to treat insomnia. Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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