Review: taking Ritalin and Topamax together


Summary

Drug interactions are reported among people who take Ritalin and Topamax together. This review analyzes the effectiveness and drug interactions between Ritalin and Topamax. It is created by eHealthMe based on reports of 403 people who take the same drugs from FDA and social media, and is updated regularly.

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Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 11,122 users)

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,310 users)

On Jul, 30, 2016

403 people who take Ritalin, Topamax are studied.


Number of reports submitted per year:

Ritalin and Topamax drug interactions.

Drug effectiveness over time:

Ritalin:
  • < 1 month: 0.0% - (0 of 9 people)
  • 1 - 6 months: 26.0% - (5 of 19 people)
  • 6 - 12 months: 66.0% - (4 of 6 people)
  • 1 - 2 years: 44.0% - (4 of 9 people)
  • 2 - 5 years: 40.0% - (4 of 10 people)
  • 5 - 10 years: 100.0% - (8 of 8 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Topamax:
  • < 1 month: 21.0% - (3 of 14 people)
  • 1 - 6 months: 60.0% - (6 of 10 people)
  • 6 - 12 months: 50.0% - (6 of 12 people)
  • 1 - 2 years: 33.0% - (5 of 15 people)
  • 2 - 5 years: 25.0% - (3 of 12 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Ritalin:
  • female: 41.0% - (24 of 58 people)
  • male: 60.0% - (3 of 5 people)
Topamax:
  • female: 36.0% - (23 of 63 people)
  • male: 40.0% - (2 of 5 people)

Drug effectiveness by age:

Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (2 of 4 people)
  • 20-29: 42.0% - (6 of 14 people)
  • 30-39: 11.0% - (2 of 17 people)
  • 40-49: 68.0% - (15 of 22 people)
  • 50-59: 33.0% - (2 of 6 people)
  • 60+: 0.0% - (0 of 0 people)
Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 61.0% - (11 of 18 people)
  • 30-39: 44.0% - (8 of 18 people)
  • 40-49: 21.0% - (5 of 23 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • mania
  • missed periods
  • nervousness
  • overdose
  • dyspnoea
  • abasia
  • agitation aggravated
  • anxiety
  • chest discomfort
  • chest pain
1 - 6 months:
  • diabetes mellitus
  • suicidal ideation
  • neuropathy peripheral
  • type 2 diabetes mellitus
  • hernia
  • hyperglycaemia
  • missed periods
  • acne
  • alopecia
  • bloating
6 - 12 months:
  • suicidal ideation
  • diabetes mellitus
  • neuropathy peripheral
  • type 2 diabetes mellitus
  • abdominal mass
  • chest pain
  • delusion
  • dyspnoea
  • eye pain
  • fatigue
1 - 2 years:
  • red eyes
  • chest pressure sensation
  • shortness of breath
  • alopecia
  • amnesia
  • anorexia
  • anxiety
  • arthralgia
  • back pain
  • balance disorder
2 - 5 years:
  • deep vein thrombosis
  • pain in extremity
  • cough
  • abdominal pain
  • biliary dyskinesia
  • chest pain
  • cholecystitis chronic
  • diarrhoea
  • dyspnoea
  • dyspnoea exertional
5 - 10 years:
  • simple partial seizures
  • confusion
  • fatigue
10+ years:
  • chest pain
  • confusional state
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fall
  • headache
  • inflammatory pain
  • insomnia related to another mental condition
  • loss of appetite
  • loss of control of legs
  • muscle contractions involuntary
not specified:
  • weight increased
  • diabetes mellitus
  • convulsion
  • headache
  • insomnia
  • nausea
  • tremor
  • fatigue
  • pyrexia
  • deep vein thrombosis

Most common drug interactions by gender *:

female:
  • weight increased
  • nausea
  • convulsion
  • deep vein thrombosis
  • diabetes mellitus
  • headache
  • fatigue
  • abdominal pain
  • pain in extremity
  • tremor
male:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • suicidal ideation
  • pyrexia
  • psychotic disorder
  • weight increased
  • decreased appetite
  • neuropathy peripheral
  • hyperglycaemia
  • insomnia

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • abasia
  • aggression
  • decreased appetite
  • malaise
  • social avoidant behaviour
  • upper respiratory tract infection
  • depressed level of consciousness
  • slow response to stimuli
  • abnormal behaviour
  • agitation
10-19:
  • diabetes mellitus
  • convulsion
  • electrocardiogram qt shortened
  • obesity
  • psychotic disorder
  • speech disorder
  • suicidal ideation
  • type 2 diabetes mellitus
  • corneal abrasion
  • hypercholesterolaemia
20-29:
  • pain in extremity
  • deep vein thrombosis
  • nausea
  • rash
  • weight decreased
  • hypokalaemia
  • abdominal pain
  • cholecystitis chronic
  • vomiting
  • chest pain
30-39:
  • weight increased
  • abdominal pain
  • diabetes mellitus
  • headache
  • insomnia
  • tremor
  • fatigue
  • pruritus
  • anxiety
  • arthralgia
40-49:
  • pyrexia
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • confusional state
  • disturbance in attention
  • drug ineffective
  • pneumonia
  • weight increased
  • flushing
50-59:
  • suicidal ideation
  • pain
  • pain in extremity
  • diabetes mellitus
  • nausea
  • type 2 diabetes mellitus
  • amnesia
  • fall
  • fatigue
  • hallucination
60+:
  • suicidal ideation
  • diabetes mellitus
  • deep vein thrombosis
  • oedema peripheral
  • swelling face
  • neuropathy peripheral
  • type 2 diabetes mellitus
  • amnesia
  • aphasia
  • confusional state

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Topamax (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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