Review: taking Ritalin and Topamax together


Summary

Drug interactions are reported among people who take Ritalin and Topamax together. This review analyzes the effectiveness and drug interactions between Ritalin and Topamax. It is created by eHealthMe based on reports of 689 people who take the same drugs from FDA and social media, and is updated regularly.

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Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 14,979 users)

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 34,483 users)

On Sep, 18, 2016

689 people who take Ritalin, Topamax are studied.


Number of reports submitted per year:

Ritalin and Topamax drug interactions.

Drug effectiveness over time:

Ritalin:
  • < 1 month: 0.0% - (0 of 10 people)
  • 1 - 6 months: 29.0% - (5 of 17 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 50.0% - (4 of 8 people)
  • 2 - 5 years: 45.0% - (5 of 11 people)
  • 5 - 10 years: 100.0% - (3 of 3 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Topamax:
  • < 1 month: 25.0% - (3 of 12 people)
  • 1 - 6 months: 54.0% - (6 of 11 people)
  • 6 - 12 months: 50.0% - (6 of 12 people)
  • 1 - 2 years: 45.0% - (5 of 11 people)
  • 2 - 5 years: 25.0% - (3 of 12 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Ritalin:
  • female: 37.0% - (20 of 53 people)
  • male: 60.0% - (3 of 5 people)
Topamax:
  • female: 39.0% - (23 of 58 people)
  • male: 40.0% - (2 of 5 people)

Drug effectiveness by age:

Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (2 of 4 people)
  • 20-29: 42.0% - (6 of 14 people)
  • 30-39: 17.0% - (3 of 17 people)
  • 40-49: 58.0% - (10 of 17 people)
  • 50-59: 33.0% - (2 of 6 people)
  • 60+: 0.0% - (0 of 0 people)
Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 61.0% - (11 of 18 people)
  • 30-39: 44.0% - (8 of 18 people)
  • 40-49: 27.0% - (5 of 18 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • nervousness
  • overdose
  • anxiety
  • depression
  • dyspnoea
  • mania
  • missed periods
  • drug effect decreased
  • drug ineffective
  • fall
1 - 6 months:
  • diabetes mellitus
  • suicidal ideation
  • neuropathy peripheral
  • type 2 diabetes mellitus
  • hernia
  • hyperglycaemia
  • depression
  • drug ineffective
  • loss of consciousness
  • missed periods
6 - 12 months:
  • suicidal ideation
  • diabetes mellitus
  • fatigue
  • neuropathy peripheral
  • type 2 diabetes mellitus
  • abdominal mass
  • chest pain
  • delusion
  • drug ineffective
  • dyspnoea
1 - 2 years:
  • red eyes
  • cerebral atrophy
  • chest pressure sensation
  • drug intolerance
  • shortness of breath
  • abdominal pain
  • alopecia
  • amnesia
  • anorexia
  • anxiety
2 - 5 years:
  • deep vein thrombosis
  • pain in extremity
  • cough
  • abdominal pain
  • biliary dyskinesia
  • chest pain
  • cholecystitis chronic
  • diarrhoea
  • dyspnoea
  • dyspnoea exertional
5 - 10 years:
  • emotional distress
  • gynaecomastia
  • obesity
  • simple partial seizures
  • confusion
  • fatigue
10+ years:
  • pre-existing condition improved
  • weight decreased
  • benign prostatic hyperplasia
  • chest pain
  • confusional state
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fall
  • headache
  • hepatic enzyme increased
  • hypertension
not specified:
  • headache
  • weight increased
  • fatigue
  • depression
  • nausea
  • insomnia
  • drug ineffective
  • anxiety
  • convulsion
  • pain in extremity

Most common drug interactions by gender *:

female:
  • headache
  • fatigue
  • nausea
  • weight increased
  • depression
  • drug ineffective
  • dyspnoea
  • pain in extremity
  • anxiety
  • insomnia
male:
  • diabetes mellitus
  • deep vein thrombosis
  • pyrexia
  • type 2 diabetes mellitus
  • mental status changes
  • suicidal ideation
  • weight increased
  • brain oedema
  • carotid artery thrombosis
  • cerebral haemorrhage

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • abasia
  • aggression
  • decreased appetite
  • malaise
  • nausea
  • social avoidant behaviour
  • lethargy
  • abdominal pain upper
  • drug intolerance
  • emotional distress
10-19:
  • convulsion
  • diabetes mellitus
  • drug ineffective
  • decreased appetite
  • emotional distress
  • insomnia
  • weight decreased
  • aggression
  • electrocardiogram qt shortened
  • injury
20-29:
  • pain in extremity
  • deep vein thrombosis
  • dyspnoea
  • fatigue
  • weight increased
  • insomnia
  • nausea
  • rash
  • depression
  • dysarthria
30-39:
  • depression
  • headache
  • fatigue
  • abdominal pain
  • nausea
  • weight increased
  • diabetes mellitus
  • vomiting
  • pruritus
  • insomnia
40-49:
  • confusional state
  • headache
  • type 2 diabetes mellitus
  • drug ineffective
  • pyrexia
  • balance disorder
  • pain
  • weight increased
  • convulsion
  • blood cholesterol increased
50-59:
  • nausea
  • suicidal ideation
  • pain
  • weight decreased
  • pain in extremity
  • fall
  • diabetes mellitus
  • fatigue
  • hallucination
  • insomnia
60+:
  • diabetes mellitus
  • dyspnoea
  • suicidal ideation
  • fatigue
  • oedema peripheral
  • neuropathy peripheral
  • deep vein thrombosis
  • fall
  • hypoaesthesia
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Topamax (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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