Review: taking Ritalin and Wellbutrin together


Summary

Drug interactions are reported among people who take Ritalin and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Ritalin and Wellbutrin. It is created by eHealthMe based on reports of 2,417 people who take the same drugs from FDA and social media, and is updated regularly.

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Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 15,966 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 70,675 users)

On Nov, 17, 2016

2,417 people who take Ritalin, Wellbutrin are studied.


Number of reports submitted per year:

Ritalin and Wellbutrin drug interactions.

Drug effectiveness over time:

Ritalin:
  • < 1 month: 35.0% - (12 of 34 people)
  • 1 - 6 months: 44.0% - (26 of 59 people)
  • 6 - 12 months: 39.0% - (13 of 33 people)
  • 1 - 2 years: 38.0% - (15 of 39 people)
  • 2 - 5 years: 50.0% - (28 of 55 people)
  • 5 - 10 years: 84.0% - (21 of 25 people)
  • 10+ years: 66.0% - (16 of 24 people)
  • not specified: 50.0% - (2 of 4 people)
Wellbutrin:
  • < 1 month: 9.0% - (2 of 21 people)
  • 1 - 6 months: 25.0% - (11 of 44 people)
  • 6 - 12 months: 16.0% - (5 of 30 people)
  • 1 - 2 years: 41.0% - (16 of 39 people)
  • 2 - 5 years: 40.0% - (27 of 66 people)
  • 5 - 10 years: 47.0% - (19 of 40 people)
  • 10+ years: 60.0% - (21 of 35 people)
  • not specified: 50.0% - (3 of 6 people)

Drug effectiveness by gender:

Ritalin:
  • female: 46.0% - (87 of 188 people)
  • male: 54.0% - (46 of 85 people)
Wellbutrin:
  • female: 37.0% - (74 of 196 people)
  • male: 35.0% - (30 of 85 people)

Drug effectiveness by age:

Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 53.0% - (8 of 15 people)
  • 20-29: 46.0% - (19 of 41 people)
  • 30-39: 34.0% - (23 of 67 people)
  • 40-49: 58.0% - (42 of 72 people)
  • 50-59: 48.0% - (27 of 56 people)
  • 60+: 63.0% - (14 of 22 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 38.0% - (5 of 13 people)
  • 20-29: 24.0% - (11 of 45 people)
  • 30-39: 36.0% - (25 of 69 people)
  • 40-49: 40.0% - (30 of 75 people)
  • 50-59: 38.0% - (22 of 57 people)
  • 60+: 50.0% - (11 of 22 people)

Most common drug interactions over time *:

< 1 month:
  • fatigue
  • insomnia
  • drug ineffective
  • suicidal ideation
  • tremor
  • anxiety
  • headache
  • depression
  • dry mouth
  • feeling abnormal
1 - 6 months:
  • anxiety
  • fatigue
  • diabetes mellitus
  • insomnia
  • suicidal ideation
  • abdominal pain
  • convulsion
  • feeling abnormal
  • panic attack
  • somnolence
6 - 12 months:
  • depression
  • anxiety
  • diabetes mellitus
  • suicidal ideation
  • type 2 diabetes mellitus
  • arthralgia
  • drug ineffective
  • insomnia
  • memory impairment
  • neuropathy peripheral
1 - 2 years:
  • anxiety
  • back pain
  • fatigue
  • nausea
  • depression
  • headache
  • arthralgia
  • breast cancer
  • breast cancer in situ
  • breast cyst
2 - 5 years:
  • anxiety
  • fatigue
  • depression
  • irritability
  • dizziness
  • memory impairment
  • nausea
  • hair loss
  • pain
  • abdominal pain
5 - 10 years:
  • fatigue
  • vision blurred
  • dizziness
  • blue vision
  • depression
  • dry mouth
  • hand tremor
  • anxiety aggravated
  • brain mass
  • gynaecomastia
10+ years:
  • altered visual depth perception
  • aphasia
  • depression
  • numbness and tingling
  • tinnitus
  • vertigo
  • dry mouth
  • erectile dysfunction
  • anxiety
  • asthma
not specified:
  • depression
  • nausea
  • fatigue
  • pain
  • anxiety
  • drug ineffective
  • fall
  • weight decreased
  • vomiting
  • insomnia

Most common drug interactions by gender *:

female:
  • depression
  • fatigue
  • nausea
  • anxiety
  • drug ineffective
  • pain
  • headache
  • vomiting
  • fall
  • insomnia
male:
  • depression
  • fatigue
  • pain
  • insomnia
  • nausea
  • anxiety
  • confusional state
  • disturbance in attention
  • weight decreased
  • hypertension

Most common drug interactions by age *:

0-1:
  • back pain
  • balance disorder
  • blood cholesterol increased
  • blood triglycerides increased
  • bradycardia
  • bundle branch block right
  • cerumen impaction
  • chest pain
  • cholecystitis chronic
  • convulsion
2-9:
  • application site erythema
  • chest pain
  • anxiety
  • speech disorder
  • agitation
  • application site pruritus
  • asthenia
  • insomnia
  • pain
  • pyrexia
10-19:
  • drug ineffective
  • fatigue
  • grand mal convulsion
  • weight increased
  • anxiety
  • insomnia
  • nausea
  • decreased appetite
  • diabetes mellitus
  • pain
20-29:
  • tremor
  • fatigue
  • completed suicide
  • headache
  • weight increased
  • cardiac arrest
  • dysarthria
  • aphasia
  • arthralgia
  • dyspnoea
30-39:
  • nausea
  • fatigue
  • anxiety
  • depression
  • drug ineffective
  • diarrhoea
  • vomiting
  • suicidal ideation
  • feeling abnormal
  • insomnia
40-49:
  • depression
  • nausea
  • fatigue
  • dizziness
  • fall
  • anxiety
  • pain
  • vision blurred
  • back pain
  • constipation
50-59:
  • depression
  • fatigue
  • pain
  • nausea
  • anxiety
  • weight decreased
  • dizziness
  • asthenia
  • arthralgia
  • insomnia
60+:
  • depression
  • nausea
  • fall
  • back pain
  • pain
  • decreased appetite
  • pain in extremity
  • weight decreased
  • asthenia
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Ritalin and Wellbutrin?

On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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More questions for: Ritalin, Wellbutrin

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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