Review: taking Ritalin and Wellbutrin together


Summary

Drug interactions are reported among people who take Ritalin and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Ritalin and Wellbutrin. It is created by eHealthMe based on reports of 2,228 people who take the same drugs from FDA and social media, and is updated regularly.

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Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 14,979 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 69,048 users)

On Sep, 15, 2016

2,228 people who take Ritalin, Wellbutrin are studied.


Number of reports submitted per year:

Ritalin and Wellbutrin drug interactions.

Drug effectiveness over time:

Ritalin:
  • < 1 month: 35.0% - (12 of 34 people)
  • 1 - 6 months: 44.0% - (26 of 58 people)
  • 6 - 12 months: 39.0% - (13 of 33 people)
  • 1 - 2 years: 38.0% - (15 of 39 people)
  • 2 - 5 years: 50.0% - (28 of 55 people)
  • 5 - 10 years: 83.0% - (20 of 24 people)
  • 10+ years: 65.0% - (15 of 23 people)
  • not specified: 50.0% - (2 of 4 people)
Wellbutrin:
  • < 1 month: 10.0% - (2 of 20 people)
  • 1 - 6 months: 25.0% - (11 of 44 people)
  • 6 - 12 months: 16.0% - (5 of 30 people)
  • 1 - 2 years: 41.0% - (16 of 39 people)
  • 2 - 5 years: 40.0% - (27 of 66 people)
  • 5 - 10 years: 48.0% - (19 of 39 people)
  • 10+ years: 61.0% - (21 of 34 people)
  • not specified: 50.0% - (3 of 6 people)

Drug effectiveness by gender:

Ritalin:
  • female: 45.0% - (85 of 185 people)
  • male: 54.0% - (46 of 85 people)
Wellbutrin:
  • female: 38.0% - (74 of 193 people)
  • male: 35.0% - (30 of 85 people)

Drug effectiveness by age:

Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 53.0% - (8 of 15 people)
  • 20-29: 47.0% - (19 of 40 people)
  • 30-39: 34.0% - (23 of 67 people)
  • 40-49: 57.0% - (41 of 71 people)
  • 50-59: 48.0% - (27 of 56 people)
  • 60+: 61.0% - (13 of 21 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 38.0% - (5 of 13 people)
  • 20-29: 25.0% - (11 of 44 people)
  • 30-39: 36.0% - (25 of 69 people)
  • 40-49: 40.0% - (30 of 74 people)
  • 50-59: 38.0% - (22 of 57 people)
  • 60+: 52.0% - (11 of 21 people)

Most common drug interactions over time *:

< 1 month:
  • fatigue
  • insomnia
  • suicidal ideation
  • anxiety
  • headache
  • tremor
  • depression
  • drug ineffective
  • irritability
  • malaise
1 - 6 months:
  • anxiety
  • diabetes mellitus
  • fatigue
  • insomnia
  • suicidal ideation
  • abdominal pain
  • convulsion
  • panic attack
  • chest pain
  • feeling abnormal
6 - 12 months:
  • depression
  • anxiety
  • diabetes mellitus
  • suicidal ideation
  • type 2 diabetes mellitus
  • arthralgia
  • memory impairment
  • neuropathy peripheral
  • add
  • anxiety disorder
1 - 2 years:
  • anxiety
  • back pain
  • depression
  • fatigue
  • headache
  • arthralgia
  • breast cancer
  • breast cancer in situ
  • breast cyst
  • breast dysplasia
2 - 5 years:
  • fatigue
  • anxiety
  • depression
  • irritability
  • dizziness
  • memory impairment
  • nausea
  • hair loss
  • abdominal pain
  • agitation
5 - 10 years:
  • fatigue
  • vision blurred
  • dizziness
  • blue vision
  • depression
  • dry mouth
  • hand tremor
  • anxiety aggravated
  • brain mass
  • gynaecomastia
10+ years:
  • altered visual depth perception
  • aphasia
  • numbness and tingling
  • tinnitus
  • vertigo
  • dry mouth
  • depression
  • erectile dysfunction
  • back pain
  • irritability
not specified:
  • depression
  • nausea
  • fatigue
  • pain
  • anxiety
  • fall
  • insomnia
  • vomiting
  • weight decreased
  • back pain

Most common drug interactions by gender *:

female:
  • depression
  • fatigue
  • nausea
  • anxiety
  • pain
  • headache
  • asthenia
  • vomiting
  • fall
  • drug ineffective
male:
  • depression
  • fatigue
  • pain
  • nausea
  • insomnia
  • disturbance in attention
  • anxiety
  • weight decreased
  • confusional state
  • hypertension

Most common drug interactions by age *:

0-1:
  • back pain
  • balance disorder
  • blood cholesterol increased
  • blood triglycerides increased
  • bradycardia
  • bundle branch block right
  • cerumen impaction
  • chest pain
  • cholecystitis chronic
  • convulsion
2-9:
  • application site erythema
  • chest pain
  • anxiety
  • speech disorder
  • agitation
  • application site pruritus
  • asthenia
  • insomnia
  • pain
  • pyrexia
10-19:
  • fatigue
  • grand mal convulsion
  • weight increased
  • anxiety
  • insomnia
  • drug ineffective
  • nausea
  • decreased appetite
  • diabetes mellitus
  • pain
20-29:
  • tremor
  • completed suicide
  • fatigue
  • headache
  • weight increased
  • cardiac arrest
  • dysarthria
  • aphasia
  • arthralgia
  • dyspnoea
30-39:
  • nausea
  • fatigue
  • anxiety
  • depression
  • diarrhoea
  • vomiting
  • suicidal ideation
  • drug ineffective
  • feeling abnormal
  • suicide attempt
40-49:
  • depression
  • fatigue
  • nausea
  • fall
  • anxiety
  • dizziness
  • pain
  • vision blurred
  • back pain
  • constipation
50-59:
  • depression
  • fatigue
  • pain
  • nausea
  • weight decreased
  • dizziness
  • anxiety
  • asthenia
  • arthralgia
  • insomnia
60+:
  • depression
  • nausea
  • back pain
  • fall
  • pain
  • pain in extremity
  • decreased appetite
  • asthenia
  • vomiting
  • weight decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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