Review: taking Rituxan and Benadryl together


Summary

Drug interactions are reported among people who take Rituxan and Benadryl together. This review analyzes the effectiveness and drug interactions between Rituxan and Benadryl. It is created by eHealthMe based on reports of 1,258 people who take the same drugs from FDA and social media, and is updated regularly.

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Rituxan

Rituxan has active ingredients of rituximab. It is often used in non-hodgkin's lymphoma. (latest outcomes from Rituxan 12,844 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 33,627 users)

On Aug, 27, 2016

1,258 people who take Rituxan, Benadryl are studied.


Number of reports submitted per year:

Rituxan and Benadryl drug interactions.

Drug effectiveness over time:

Rituxan:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Rituxan:
  • female: 0.0% - (0 of 1 people)
  • male: 0.0% - (0 of 0 people)
Benadryl:
  • female: 0.0% - (0 of 1 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Rituxan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • infusion related reaction
  • nausea
  • dyspnoea
  • pyrexia
  • chest pain
  • hypotension
  • drug ineffective
  • vomiting
  • chills
  • fatigue
1 - 6 months:
  • febrile neutropenia
  • sepsis
  • pneumonia
  • fatigue
  • dyspnoea
  • pyrexia
  • platelet count decreased
  • respiratory failure
  • asthenia
  • insomnia
6 - 12 months:
  • drug ineffective
  • death
  • infusion related reaction
  • weight decreased
  • nausea
  • back pain
  • convulsion
  • hypotension
  • neutropenia
  • vomiting
1 - 2 years:
  • drug ineffective
  • arthralgia
  • neoplasm malignant
  • pain in extremity
  • pneumonia
  • abdominal discomfort
  • acne
  • adverse event
  • blood cholesterol increased
  • blood creatinine increased
2 - 5 years:
  • lower respiratory tract infection
  • nasopharyngitis
  • pneumonia
  • suicidal ideation
  • drug ineffective
  • arthralgia
  • death
  • headache
  • vomiting
  • intervertebral disc disorder
10+ years:
  • fluid retention
  • hyperglycaemia
  • hypotension
  • vision blurred
not specified:
  • nausea
  • blood pressure increased
  • dyspnoea
  • fatigue
  • hypotension
  • emotional distress
  • pain
  • pyrexia
  • arthralgia
  • asthenia

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • dyspnoea
  • arthralgia
  • hypotension
  • infusion related reaction
  • weight decreased
  • headache
  • pain
  • drug ineffective
male:
  • blood pressure increased
  • emotional distress
  • dyspnoea
  • death
  • pyrexia
  • nausea
  • hypotension
  • chills
  • cough
  • pneumonia

Most common drug interactions by age *:

0-1:
  • agitation
  • bacteraemia
  • bacteria stool identified
  • blood pressure increased
  • bradycardia
  • bronchial hyperreactivity
  • bronchial obstruction
  • bronchospasm
  • catheter related infection
  • central line infection
2-9:
  • catheter related infection
  • gastroenteritis viral
  • heart rate increased
  • meningitis aseptic
  • moraxella infection
  • pseudomonas infection
  • respiratory distress
  • retching
  • tracheobronchitis
  • alpha haemolytic streptococcal infection
10-19:
  • dyspnoea
  • infusion related reaction
  • body temperature increased
  • chills
  • cyanosis
  • malaise
  • nausea
  • pyrexia
  • swollen tongue
  • vomiting
20-29:
  • nausea
  • asthenia
  • dyspnoea
  • urinary tract infection
  • vomiting
  • anaemia
  • conjunctivitis viral
  • deep vein thrombosis
  • insomnia
  • gastritis
30-39:
  • pyrexia
  • stomatitis
  • nausea
  • dyspnoea
  • headache
  • hepatitis
  • laboratory test abnormal
  • infusion related reaction
  • rash
  • abdominal pain
40-49:
  • pneumonia
  • nausea
  • bronchitis
  • febrile neutropenia
  • hip arthroplasty
  • stomatitis
  • headache
  • pneumonia aspiration
  • infusion related reaction
  • cystitis
50-59:
  • hypotension
  • nausea
  • vomiting
  • arthralgia
  • fatigue
  • infusion related reaction
  • weight decreased
  • dyspnoea
  • pain
  • pyrexia
60+:
  • hypotension
  • dyspnoea
  • pyrexia
  • fatigue
  • infusion related reaction
  • nausea
  • asthenia
  • pneumonia
  • arthralgia
  • blood pressure increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Rituxan (rituximab) is often used to treat non-hodgkin's lymphoma. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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