Review: taking Savella and Naproxen together


Summary

Drug interactions are reported among people who take Savella and Naproxen together. This review analyzes the effectiveness and drug interactions between Savella and Naproxen. It is created by eHealthMe based on reports of 92 people who take the same drugs from FDA and social media, and is updated regularly.

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Savella

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 4,722 users)

Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 36,950 users)

On Sep, 01, 2016

92 people who take Savella, Naproxen are studied.


Number of reports submitted per year:

Savella and Naproxen drug interactions.

Drug effectiveness over time:

Savella:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Naproxen:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Savella:
  • female: 37.0% - (3 of 8 people)
  • male: 0.0% - (0 of 0 people)
Naproxen:
  • female: 45.0% - (5 of 11 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Savella:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 0 people)
Naproxen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • pruritus
  • feeling hot
  • muscle spasms
  • abdominal pain upper
  • agitation
  • blood creatinine increased
  • blood sodium decreased
  • fatigue
  • feeling cold
1 - 6 months:
  • depression
  • alexia
  • anxiety aggravated
  • burning mouth syndrome
  • dry mouth
  • frequent headaches
  • muscle cramps aggravated
  • proteinuria
  • rash psoriaform
  • stomach pain
6 - 12 months:
  • renal failure acute
  • alexia
  • bone and joint pain
  • fatigue
  • hot flashes
  • impaired memory
  • nausea
  • swelling
  • weakness
1 - 2 years:
  • hair loss
2 - 5 years:
  • hair loss
  • rash psoriaform
5 - 10 years:
  • anxiety aggravated
  • burning mouth syndrome
  • dry mouth
  • frequent headaches
  • muscle cramps aggravated
  • stomach pain
10+ years:
  • proteinuria
not specified:
  • arthralgia
  • depression
  • drug hypersensitivity
  • pain
  • vomiting
  • cataract
  • glaucoma
  • pain in extremity
  • rash
  • fatigue

Most common drug interactions by gender *:

female:
  • depression
  • nausea
  • pain
  • vomiting
  • drug hypersensitivity
  • fatigue
  • cataract
  • insomnia
  • pruritus
  • arthralgia
male:
  • urinary retention
  • arthralgia
  • decreased immune responsiveness
  • furuncle
  • immunosuppression
  • sleep disorder
  • wheezing
  • dysuria
  • headache
  • muscle spasms

Most common drug interactions by age *:

20-29:
  • abdominal discomfort
  • adverse event
  • anxiety aggravated
  • blood cholesterol increased
  • burning mouth syndrome
  • cataract
  • diabetes mellitus
  • drug hypersensitivity
  • dry mouth
  • fluid retention
30-39:
  • abnormal loss of weight
  • drug ineffective
  • nausea
  • cellulitis
  • tachycardia
  • depression
  • pruritus
  • suicidal ideation
  • vomiting
  • abdominal discomfort
40-49:
  • pain in extremity
  • back pain
  • hyperhidrosis
  • arthralgia
  • hot flush
  • poor quality sleep
  • weight increased
  • pain
  • abscess
  • binge eating
50-59:
  • renal failure acute
  • candidiasis
  • onychomycosis
  • urinary tract infection
  • vitamin d decreased
  • abdominal pain upper
  • blood creatinine increased
  • blood sodium decreased
  • drug hypersensitivity
  • myalgia
60+:
  • feeling hot
  • pruritus
  • fatigue
  • insomnia
  • oedema peripheral
  • agitation
  • cataract
  • chills
  • depression
  • drug hypersensitivity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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