Review: taking Savella and Naproxen together


Summary

Drug interactions are reported among people who take Savella and Naproxen together. This review analyzes the effectiveness and drug interactions between Savella and Naproxen. It is created by eHealthMe based on reports of 62 people who take the same drugs from FDA and social media, and is updated regularly.

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Savella

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,324 users)

Naproxen

Naproxen has active ingredients of naproxen. It is often used in pain. (latest outcomes from Naproxen 23,478 users)

On Jul, 29, 2016

62 people who take Savella, Naproxen are studied.


Number of reports submitted per year:

Savella and Naproxen drug interactions.

Drug effectiveness over time:

Savella:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 25.0% - (1 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Naproxen:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Savella:
  • female: 33.0% - (3 of 9 people)
  • male: 0.0% - (0 of 0 people)
Naproxen:
  • female: 41.0% - (5 of 12 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Savella:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 0 people)
Naproxen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 20.0% - (1 of 5 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • pruritus
  • muscle spasms
  • feeling hot
  • abdominal pain upper
  • agitation
  • blood creatinine increased
  • blood sodium decreased
  • feeling cold
  • hot flush
1 - 6 months:
  • depression
  • alexia
  • anxiety aggravated
  • burning mouth syndrome
  • dry mouth
  • frequent headaches
  • muscle cramps aggravated
  • proteinuria
  • rash psoriaform
  • stomach pain
6 - 12 months:
  • renal failure acute
  • alexia
  • bone and joint pain
  • fatigue
  • hot flashes
  • impaired memory
  • nausea
  • swelling
  • weakness
1 - 2 years:
  • hair loss
2 - 5 years:
  • hair loss
  • rash psoriaform
5 - 10 years:
  • anxiety aggravated
  • burning mouth syndrome
  • dry mouth
  • frequent headaches
  • muscle cramps aggravated
  • stomach pain
10+ years:
  • proteinuria
not specified:
  • cataract
  • glaucoma
  • vomiting
  • blood cholesterol increased
  • depression
  • diabetes mellitus
  • drug hypersensitivity
  • drug ineffective
  • insomnia
  • nausea

Most common drug interactions by gender *:

female:
  • nausea
  • cataract
  • insomnia
  • pruritus
  • depression
  • vomiting
  • glaucoma
  • hot flush
  • blood cholesterol increased
  • diabetes mellitus
male:
  • urinary retention
  • dysuria
  • headache
  • muscle spasms
  • nausea
  • pain of skin
  • sensation of heaviness
  • arthralgia
  • neuropathy peripheral
  • plantar fasciitis

Most common drug interactions by age *:

20-29:
  • anxiety aggravated
  • burning mouth syndrome
  • dry mouth
  • frequent headaches
  • muscle cramps aggravated
  • stomach pain
30-39:
  • abnormal loss of weight
  • drug ineffective
  • nausea
  • cellulitis
  • tachycardia
  • depression
  • pruritus
  • suicidal ideation
  • vomiting
  • bone and joint pain
40-49:
  • hyperhidrosis
  • hot flush
  • body temperature increased
  • cognitive disorder
  • nausea
  • poor quality sleep
  • muscle spasms
  • muscle twitching
  • pain
  • sensation of heaviness
50-59:
  • candidiasis
  • onychomycosis
  • urinary tract infection
  • vitamin d decreased
  • abdominal pain upper
  • blood creatinine increased
  • blood sodium decreased
  • myalgia
  • weight decreased
  • cutaneous lupus erythematosus
60+:
  • pruritus
  • feeling hot
  • insomnia
  • oedema peripheral
  • agitation
  • cataract
  • feeling cold
  • muscle spasms
  • paraesthesia oral
  • restless legs syndrome

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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